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DNA damage and biological expression of...
Journal article

DNA damage and biological expression of adenovirus: a comparison of liquid versus frozen conditions of exposure to gamma rays.

Abstract

Human adenovirus type 2 (Ad 2) was irradiated with 137Cs gamma rays in the liquid state at 0 degree C. DNA breaks were correlated with the inactivation of several viral functions and compared to results obtained previously for irradiation of Ad 2 under frozen conditions at -75 degrees C. Irradiation at 0 degree C induced 170 +/- 20 single-strand breaks and 2.6 +/- 0.4 double-strand breaks/Gy/10(12) Da in the viral DNA. Viral adsorption to human …

Authors

Bennett CB; Rainbow AJ

Journal

Radiation Research, Vol. 120, No. 1, pp. 102–112

Publisher

JSTOR

Publication Date

October 1989

DOI

10.2307/3577637

ISSN

0033-7587