Journal article
Oxidative stress and the mitochondrial theory of aging in human skeletal muscle
Abstract
According to the mitochondrial theory of aging, an age-related increase in oxidative stress is responsible for cellular damage and ultimately cell death. Despite compelling evidence that supports the mitochondrial theory of aging in some tissues, data regarding aging skeletal muscle are inconsistent. We collected resting muscle biopsies from the vastus lateralis, and 24 h urine samples from, young (N = 12, approximately 22 yr), and older (N = …
Authors
Gianni P; Jan KJ; Douglas MJ; Stuart PM; Tarnopolsky MA
Journal
Experimental Gerontology, Vol. 39, No. 9, pp. 1391–1400
Publisher
Elsevier
Publication Date
September 2004
DOI
10.1016/j.exger.2004.06.002
ISSN
0531-5565