Journal article
Role of RAD9-dependent cell-cycle checkpoints in the adaptive response to ionizing radiation in yeast, Saccharomyces cerevisiae
Abstract
PURPOSE: To determine whether yeast cells (Saccharomyces cerevisiae) defective in damage-inducible cell-cycle arrest can invoke an adaptive response and become resistant to normally lethal doses of ionizing radiation.
MATERIALS AND METHODS: Wild-type yeast cells, cells defective for DNA-damage-responsive G1 and G2 cell-cycle arrest (rad9delta), and cells defective for recombinational repair of DNA damage (rad50, 51, 52) were subjected to …
Authors
Dolling JA; Boreham DR; Bahen ME; Mitchel RE
Journal
International Journal of Radiation Biology, Vol. 76, No. 9, pp. 1273–1279
Publisher
Taylor & Francis
Publication Date
January 2000
DOI
10.1080/09553000050134500
ISSN
0955-3002