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Host cell reactivation of irradiated adenovirus in...
Journal article

Host cell reactivation of irradiated adenovirus in UV-sensitive Chinese hamster ovary cell mutants

Abstract

In this study we have utilized the ability of rodent cells to replicate viral DNA following semi-permissive infection by human adenovirus (Ad) to examine the host cell reactivation (HCR) of radiation-damaged Ad in several UV-sensitive Chinese hamster ovary (CHO) cell mutants. A significant reduction in HCR of viral DNA synthesis for UV-irradiated Ad was detected in a series of UV-sensitive mutants from complementation groups 1-6 derived from …

Authors

Arnold WRG; Rainbow AJ

Journal

Mutagenesis, Vol. 11, No. 1, pp. 89–94

Publisher

Oxford University Press (OUP)

Publication Date

1996

DOI

10.1093/mutage/11.1.89

ISSN

0267-8357