Drug Resistance Concept

subject area of

• A Mutation in the Intracellular Loop III/IV of Mosquito Sodium Channel Synergizes the Effect of Mutations in Helix IIS6 on Pyrethroid Resistance  Academic Article
• A comparison of membrane properties and composition between cell lines selected and transfected for multi-drug resistance  Academic Article
• A new perspective on concepts of asthma severity and control  Academic Article
• A randomized trial comparing activated thromboplastin time with heparin assay in patients with acute venous thromboembolism requiring large daily doses of heparin  Academic Article
• Absence of gene amplification in human cell mutants resistant to cardiac glycosides  Academic Article
• Acetylsalicylic acid resistance and clinical outcome – the Hobikoglu study is worth noting  Academic Article
• Addition of verapamil and tamoxifen to the initial chemotherapy of small cell lung cancer a phase I/II study  Academic Article
• Allostery Trumps Antibiotic Resistance  Academic Article
• Altered plasma membrane ultrastructure in multidrug-resistant cells  Academic Article
• Antibiotic resistance in uncomplicated urinary tract infection: problems with interpreting cumulative resistance rates from local community laboratories.  Academic Article
• Antimicrobial resistance surveillance in the genomic age  Academic Article
• Aripiprazole Augmentation in the Treatment of Military-Related PTSD with Major Depression: a retrospective chart review  Academic Article
• Aspirin "resistance" and its impact on cardiovascular morbidity and mortality: it is real, clinically relevant and should be measured  Academic Article
• Aspirin and clopidogrel response variability: review of the published literature.  Academic Article
• Aspirin resistance  Academic Article
• Aspirin resistance  Academic Article
• Aspirin resistance and its implications in clinical practice.  Academic Article
• Aspirin resistance: Table 1  Academic Article
• Aspirin resistance: does it exist and is it an important clinical problem?  Academic Article
• Aspirin resistance: position paper of the Working Group on Aspirin Resistance  Academic Article
• Aspirin resistance:a new independent predictor of vascular events?**Editorials published in the Journal of the American College of Cardiologyreflect the views of the authors and do no necessarily represent the views of JACCor the American College of Cardiology.  Academic Article
• Aspirin “resistance” and risk of cardiovascular morbidity: systematic review and meta-analysis  Academic Article
• Autoradiographic detection of diphtheria toxin resistant mutants in human diploid fibroblasts  Academic Article
• Bacterial infection-associated improvement of platelet counts in two patients with chronic and unresponsive idiopathic thrombocytopenic purpura with normal platelet survival studies  Academic Article
• Biological basis and clinical implications of acetylsalicylic acid resistance  Academic Article
• Bismuth-Based Quadruple Therapy with Bismuth Subcitrate, Metronidazole, Tetracycline and Omeprazole in the Eradication ofHelicobacter pylori  Academic Article
• Camptothecin-resistant mutants of Chinese hamster ovary cells containing a resistant form of topoisomerase I.  Academic Article
• Carbapenem Resistance and Mortality in Institutionalized Elderly With Urinary Infection  Academic Article
• Cationic Liposomes for Direct Gene Transfer in Therapy of Cancer and Other Diseases  Academic Article
• Cellular and genetic basis for suppression of cytotoxic T cell generation by haloaromatic hydrocarbons  Academic Article
• Challenges with heparin-based anticoagulation during cardiopulmonary bypass in children: Impact of low antithrombin activity  Academic Article
• Chinese hamster ovary cell mutants specifically affected in the phosphorylation of C-purine nucleosides  Academic Article
• Clinical factors influencing the sensitivity to warfarin when restarted after surgery  Academic Article
• Clinical update on the therapeutic use of clopidogrel: treatment of acute ST-segment elevation myocardial infarction (STEMI)  Academic Article
• Combination antifol therapy: observations on the development of resistant L1210 leukemic cells in vivo.  Academic Article
• Coping With a Child With Dravet Syndrome: Insights From Families  Academic Article
• Cross resistance pattern towards anticancer drugs of a human carcinoma multidrug-resistant cell line  Academic Article
• Cross-resistance and biochemical characteristics of second-step mutants of HeLa cells resistant to cardiac glycosides  Academic Article
• Cross-resistance to cisplatin in cells resistant to photofrin-mediated photodynamic therapy.  Academic Article
• Cross-resistance to photofrin-mediated photodynamic therapy and UV light and recovery from photodynamic therapy damage in Rif-8A mouse fibrosarcoma cells measured using viral capacity  Academic Article
• DNA repair enzyme expression in chronic lymphocytic leukemia vis-à-vis nitrogen mustard drug resistance  Academic Article
• DRB resistance in Chinese hamster and human cells: Genetic and biochemical characteristics of the selection system  Academic Article
• Decreased concentration of antithrombin after preoperative therapeutic heparin does not cause heparin resistance during cardiopulmonary bypass  Academic Article
• Development of a specific assay for cardiac glycoside-like compounds based on cross-resistance of human cell mutants  Academic Article
• Development of leptin resistance in rat soleus muscle in response to high-fat diets  Academic Article
• Dimerization of the P-glycoprotein in membranes  Academic Article
• Diphtheria toxin resistance in chinese hamster cells: Genetic and biochemical characteristics of the mutants affected in protein synthesis  Academic Article
• Diphtheria toxin resistance in human lymphoblast lines  Academic Article
• Diphtheria-toxin-resistant mutants of CHO cells affected in protein synthesis: A novel phenotype  Academic Article
• Disconnect between sputum neutrophils and other measures of airway inflammation in asthma  Academic Article
• EPIDERMAL GROWTH FACTOR-MEDIATED ACTIVATION OF THE MAP KINASE CASCADE RESULTS IN ALTERED EXPRESSION AND FUNCTION OF ABCG2 (BCRP)  Academic Article
• Effect of alkyl-N-purine DNA glycosylase overexpression on cellular resistance to bifunctional alkylating agents  Academic Article
• Effectiveness of early budesonide intervention in Caucasian versus Asian patients with asthma: 3-year results of the START study  Academic Article
• Effects of salvinorin A on locomotor sensitization to D2/D3 dopamine agonist quinpirole  Academic Article
• Electrical stimulation for drug-resistant epilepsy: an evidence-based analysis.  Academic Article
• Endurance training partially reverses dietary-induced leptin resistance in rodent skeletal muscle  Academic Article
• Enhanced antiplatelet effect of clopidogrel in patients whose platelets are least inhibited by aspirin: a randomized crossover trial  Academic Article
• Evidence for functional hemizygosity at the Emtr locus in CHO cells through segregation analysis  Academic Article
• Evidence for variation in the number of functional gene copies at the AmaR locus in chinese hamster cell lines  Academic Article
• Evolving issues in the management of reflux disease?  Academic Article
• Formycin B-resistant mutants of Chinese hamster ovary cells: novel genetic and biochemical phenotype affecting adenosine kinase.  Academic Article
• Genes controlling malathion resistance in a laboratory-selected population of Drosophila melanogaster  Academic Article
• Genetic and biochemical characterization of mutants of CHO cells resistant to the protein synthesis inhibitor trichodermin  Academic Article
• Genetic and biochemical studies on mutants of CHO cells resistant to 7-deazapurine nucleosides: Differences in the mechanisms of action of toyocamycin and tubercidin  Academic Article
• Genetic and biochemical studies with mutants of mammalian cells affected in microtubule-related proteins other than tubulin: mitochondrial localization of a microtubule-related protein  Academic Article
• Genetic and biochemical studies with the adenosine analogs toyocamycin and tubercidin: Mutation at the adenosine kinase locus in Chinese hamster cells  Academic Article
• Genetic markers in mouse teratocarcinoma cells. Selection and partial characterization of mutants resistant to toyocamycin, DRB and podophyllotoxin  Academic Article
• Giardia lambliaRNA Polymerase II  Academic Article
• Gonadotrophin-releasing hormone analogue as an adjunct to gonadotropin therapy for clomiphene-resistant polycystic ovarian syndrome  Academic Article
• Gonadotrophin-releasing hormone analogue as an adjunct to gonadotropin therapy for clomiphene-resistant polycystic ovarian syndrome  Academic Article
• Griseofulvin resistance mutation of Chinese hamster ovary cells that affects the apparent molecular weight of a congruent to 200,000-dalton protein.  Academic Article
• Heparin Binding to Plasma Proteins, an Important Mechanism for Heparin Resistance  Academic Article
• Heparin resistance in acute coronary syndromes  Academic Article
• Heparin sensitivity and resistance in the neonate: An explanation  Academic Article
• High prevalence of unrecognized sleep apnoea in drug-resistant hypertension  Academic Article
• Human cell mutants affected in the interaction of the 12β-OH group of cardiac glycosides with the digitalis receptor  Academic Article
• Human fibroblast strains showing increased sensitivity or resistance to ethidium bromide  Academic Article
• Identification of 2-benzimidazolyl urea as a new antimitotic compound based on cross resistance studies with nocodazole resistant mutants of cho cells  Academic Article
• Identification of QTLs Associated with Virulence Related Traits and Drug Resistance in Cryptococcus neoformans  Academic Article
• Identification of a common protease-sensitive region in d-alanyl-d-alanine and d-alanyl-d-lactate ligases and photoaffinity labeling with 8-azido ATP  Academic Article
• Identification of a protein altered in mutants resistant to microtubule inhibitors as a member of the major heat shock protein (hsp70) family.  Academic Article
• Immunological studies with different classes of mutants affected at the adenosine kinase locus in CHO cells  Academic Article
• In Vitro Generation of Human High-Density-Lipoprotein-ResistantTrypanosoma brucei brucei  Academic Article
• In Vitro Induction of PDT Resistance in HT29, HT1376 and SK-N-MC Cells by Various Photosensitizers¶  Academic Article
• Increased DNA Synthesis and Repair-Enzyme Expression in Lymphocytes From Patients With Chronic Lymphocytic Leukemia Resistant to Nitrogen Mustards  Academic Article
• Increased accumulation of drugs in a multidrug resistant cell line by alteration of membrane biophysical properties  Academic Article
• Increased cellular internalization of amphiphiles in a multidrug-resistant CHO cell line  Academic Article
• Induced p21waf expression in H1299 cell line promotes cell senescence and protects against cytotoxic effect of radiation and doxorubicin  Academic Article
• Induction of resistance to hydrogen peroxide and radiation inDeinococcus radiodurans  Academic Article
• Inhibition of ABCC4 potentiates combination beta agonist and glucocorticoid responses in human airway epithelial cells  Academic Article
• Inhibition of metabolic cooperation by phorbol esters in a cell culture system based on adenosine kinase deficient mutants of V79 cells  Academic Article
• Interaction between serotonin transporter gene variants and life events predicts response to antidepressants in the GENDEP project  Academic Article
• Intratumoral heterogeneity: pathways to treatment resistance and relapse in human glioblastoma  Academic Article
• Intrinsic multidrug resistance phenotype of chinese hamster (rodent) cells in comparison to human cells  Academic Article
• Investigation of the relationship between altered intracellular pH and multidrug resistance in mammalian cells  Academic Article
• Involvement of adenosine kinase in the phosphorylation of formycin B in CHO cells  Academic Article
• Is there a role for laboratory testing to identify patients at risk of aspirin treatment failure?  Academic Article
• Isolation and characterization of mutants of human diploid fibroblasts resistant to diphtheria toxin.  Academic Article
• Ketoconazole in the Management of Precocious Puberty Not Responsive to LHRH-Analogue Therapy  Academic Article
• Leptin increases FA oxidation in lean but not obese human skeletal muscle: evidence of peripheral leptin resistance  Academic Article
• Local, exendin-(9—39)-insensitive, site of action of GLP-1 in canine ileum  Academic Article
• Long-duration therapy with low molecular weight heparin in patients with antiphospholipid antibody syndrome resistant to warfarin therapy  Academic Article
• MDR1transcript levels as an indication of resistant disease in acute myelogenous leukaemia  Academic Article
• Management of iliofemoral thrombosis in a pregnant patient with heparin resistance  Academic Article
• Mechanism of aminoglycoside 3'-phosphotransferase type IIIa: His188 is not a phosphate-accepting residue  Academic Article
• Mechanisms and treatments for severe, steroid-resistant allergic airway disease and asthma  Academic Article
• Microtubules, mitochondria, and molecular chaperones: a new hypothesis for in vivo assembly of microtubules  Academic Article
• Mitochondrial alterations in photodynamic therapy-resistant cells.  Academic Article
• Mitochondrial matrix localization of a protein altered in mutants resistant to the microtubule inhibitor podophyllotoxin.  Academic Article
• Modification of in vivo methotrexate antitumor effect in L1210 leukemia by induced impairment of purine salvage  Academic Article
• Modified adriamycin-vincristine-dexamethasone (m-VAD) in primary refractory and relapsed plasma cell myeloma: an NCI (Canada) pilot study. The National Cancer Institute of Canada Clinical Trials Group.  Academic Article
• Multifactorial resistance to antineoplastic agents in drug-resistant P388 murine leukemia, Chinese hamster ovary, and human HeLa cells, with emphasis on the role of DNA topoisomerase II  Academic Article
• Multiple daily doses of acetyl-salicylic acid (ASA) overcome reduced platelet response to once-daily ASA after coronary artery bypass graft surgery: a pilot randomized controlled trial  Academic Article
• Mutagenic response to ultraviolet light and X-rays at five independent genetic loci in chinese hamster ovary cells  Academic Article
• Mutagenic responses of five independent geentic loci in CHO cells to a variety of mutagens  Academic Article
• Mutants of CHO cells resistant to the protein synthesis inhibitor emetine: Genetic and biochemical characterization of second-step mutants  Academic Article
• Mutants of CHO cells resistant to the protein synthesis inhibitors, cryptopleurine and tylocrebrine: genetic and biochemical evidence for common site of action of emetine, cryptopleurine, tylocrebrine, and tubulosine  Academic Article
• Mutants of HeLa cells resistant to ouabain and cassaine: Genetic evidence for the common site of action of cardiac glycosides and erythrophleum alkaloids  Academic Article
• Mutants of chinese hamster ovary cells affected in two different microtubule-associated proteins. Genetic and biochemical studies.  Academic Article
• Nitrogen mustard drug resistant B-cell chronic lymphocytic leukemia as an in vivo model for crosslinking agent resistance  Academic Article
• Novel mutants of CHO cells resistant to adenosine analogs and containing biochemically altered form of adenosine kinase in cell extracts  Academic Article
• Occurrence of antibiotic resistance inEscherichia colifrom surface waters and fecal pollution sources near Hamilton, Ontario  Academic Article
• Oligonucleotide degradation contributes to resistance to antisense compounds  Academic Article
• Optimizing Treatment in Social Phobia: A Review of Treatment Resistance  Academic Article
• Ouabain-resistant mutants of Chinese hamster ovary cells are not directly affected in Na+, K+-ATPase  Academic Article
• P2Y12 receptor inhibitor resistance and coronary artery disease  Academic Article
• POINT: Will New Anti-eosinophilic Drugs Be Useful in Asthma Management? Yes  Academic Article
• Pactamycin resistance in CHO cells: Morphological changes induced by the drug in the wild-type and mutant cells  Academic Article
• Pharmacotherapy for social anxiety disorder: an update.  Academic Article
• Phase II Trial Evaluating the Palliative Benefit of Second-Line Zoledronic Acid in Breast Cancer Patients With Either a Skeletal-Related Event or Progressive Bone Metastases Despite First-Line Bisphosphonate Therapy  Academic Article
• Phase II study of mitomycin C and 5 fluorouracil in platinum resistant ovarian cancer.  Academic Article
• Phenotypic differences in cholinergic responses of distal colonic epithelium  Academic Article
• Podophyllotoxin resistance: A codominant selection system for quantitative mutagenesis studies in mammalian cells  Academic Article
• Podophyllotoxin-resistant mutants of Chinese hamster ovary cells. Alteration in a microtubule-associated protein.  Academic Article
• Podophyllotoxin-resistant mutants of Chinese hamster ovary cells: cross-resistance studies with various microtubule inhibitors and podophyllotoxin analogues.  Academic Article
• Point-of-care testing for assessment of adequacy of oral antiplatelet therapy in patients with cardiovascular disease  Academic Article
• Possible Roles of Exceptionally Conserved Residues around the Selectivity Filters of Sodium and Calcium Channels  Academic Article
• Potentiation of chlorambucil toxicity in B-CLL lymphocytes using the DNA synthesis inhibitors aphidicolin and 1-β-d-arabinofuranosylcytosine  Academic Article
• Pre-exposure of human squamous carcinoma cells to low-doses of gamma-rays leads to an increased resistance to subsequent low-dose cisplatin treatment  Academic Article
• Psychopharmacologic treatment of pediatric major depressive disorder  Academic Article
• Purification and properties of dihydrofolate reductase from methotrexate-sensitive and methotrexate-resistant Chinese hamster ovary cells  Academic Article
• Quetiapine augmentation of SRIs in treatment refractory obsessive-compulsive disorder: a double-blind, randomised, placebo-controlled study [ISRCTN83050762]  Academic Article
• RESISTANCE TO PHOTODYNAMIC THERAPY IN RADIATION INDUCED FIBROSARCOMA-1 and CHINESE HAMSTER OVARY-MULTI-DRUG RESISTANT CELLS in vitro  Academic Article
• Random segregation of multiple genetic markers from CHO-CHO hybrids: Evidence for random distribution of functional hemizygosity in the genome  Academic Article
• Randomized trial of high-dose cytarabine versus amsacrine in acute myelogenous leukemia in relapse: a Leukemia Intergroup Study.  Academic Article
• Real-Time PCR Assay for Rapid Detection and Analysis of PfCRT Haplotypes of Chloroquine-Resistant Plasmodium falciparum Isolates from India  Academic Article
• Refractory bipolar disorder and neuroprogression  Academic Article
• Refractory social anxiety disorder  Academic Article
• Repeated mutagenesis and the selection of recessive and dominant mutations in cultured mammalian cells  Academic Article
• Resistance to the microtubule inhibitor podophyllotoxin: Selection and partial characterization of mutants in CHO cells  Academic Article
• Reversal of intrinsic multidrug resistance in Chinese hamster ovary cells by amiloride analogs  Academic Article
• Review of aspirin and clopidogrel resistance in peripheral arterial disease  Academic Article
• Risk Factors for Resistance to Antimicrobial Agents among Nursing Home Residents  Academic Article
• Rituximab maintenance for relapsed refractory thrombotic thrombocytopenic purpura  Academic Article
• Role for NLRP3 Inflammasome–mediated, IL-1β–Dependent Responses in Severe, Steroid-Resistant Asthma  Academic Article
• Sarco(endo)plasmic reticulum Ca2+ pump isoform SERCA3 is more resistant than SERCA2b to peroxide  Academic Article
• Serum brain-derived neurotrophic factor (BDNF) is not associated with response to electroconvulsive therapy (ECT): A pilot study in drug resistant depressed patients  Academic Article
• Species-specific differences in the toxicity of puromycin towards cultured human and Chinese hamster cells  Academic Article
• Spectinomycin kinase from Legionella pneumophila. Characterization of substrate specificity and identification of catalytically important residues  Academic Article
• Splenic Radiation for Corticosteroid-resistant Immune Thrombocytopenia  Academic Article
• Streptogramin antibiotics: mode of action and resistance  Academic Article
• Structural determinants responsible for the biological activity of (-)-emetine, (-)-cryptopleurine, and (-)-tylocrebrine: structure-activity relationship among related compounds.  Academic Article
• Structure-activity study and design of multidrug-resistant reversal compounds by a computer automated structure evaluation methodology.  Academic Article
• Studies on temperature-sensitive mutants of Chinese hamster ovary cells affected in DNA synthesis  Academic Article
• Studies with a 2,4-diamino-5-(3',4'-dichlorophenyl)-6-methylpyrimidine (DDMP)-resistant L1210 leukemia cell line without cross-resistance to methotrexate  Academic Article
• Subcellular Membrane Properties in Vascular and Non-Vascular Smooth Muscles of Dahl Hypertensive Rats  Academic Article
• Superiority of Alternating Non-Cross-Resistant Chemotherapy in Extensive Small Cell Lung Cancer  Academic Article
• Sustained activation of the extracellular signal-regulated kinase pathway protects cells from photofrin-mediated photodynamic therapy.  Academic Article
• Synthesis and antimalarial evaluation of amide and urea derivatives based on the thiaplakortone A natural product scaffold  Academic Article
• Synthesis and structure-activity relationships among glycosidic derivatives of 4'-demethylepipodophyllotoxin and epipodophyllotoxin, showing VM26- and VP16-213-like activities.  Academic Article
• Taxol resistant mutants of Chinese hamster ovary cells: Genetic biochemical, and cross-resistance studies  Academic Article
• The clonogenic assay as a reproducible in vitro system to study predictive parameters of treatment outcome in acute nonlymphoblastic leukemia  Academic Article
• The genetic basis of chemical resistance  Academic Article
• The isolation and preliminary characterization of somatic cell mutants resistant to the protein synthesis inhibitor—Emetine  Academic Article
• The molecular basis of emetine resistance in chinese hamster ovary cells: Alteration in the 40S ribosomal subunit  Academic Article
• The new potent immunosuppressant FK-506 reverses multidrug resistance in Chinese hamster ovary cells.  Academic Article
• The treatment of patients with newly diagnosed poor prognosis acute myelogenous leukaemia: response to treatment and treatment failure  Academic Article
• To the editor: Are long‐acting beta‐agonists the “winning team” in childhood asthma?  Academic Article
• Topiramate augmentation in treatment-resistant obsessive–compulsive disorder: a retrospective, open-label case series  Academic Article
• Treating Generalized Anxiety Disorder With Second Generation Antipsychotics  Academic Article
• Use of genetic data to guide therapy in arterial disease  Academic Article
• Use of palliative end points to evaluate the effects of mitoxantrone and low-dose prednisone in patients with hormonally resistant prostate cancer.  Academic Article
• Weekly cyclophosphamide and alternate-day prednisone: an effective secondary therapy in multiple myeloma.  Academic Article
• When do general practitioners request urine specimens for microbiology analysis? The applicability of antibiotic resistance surveillance based on routinely collected data  Academic Article