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Species‐specific differences in the toxicity of...
Journal article

Species‐specific differences in the toxicity of puromycin towards cultured human and Chinese hamster cells

Abstract

The toxicity of the protein synthesis inhibitor puromycin towards a number of human and Chinese hamster cell lines has been examined. In comparison to cells of human origin, Chinese hamster cells exhibited about 25-fold higher resistance towards puromycin. These differences appeared to be species related as all the cell lines from any one species showed similar sensitivity towards puromycin. The incorporation of [3H]leucine in the hamster cell …

Authors

Dudani AK; Gupta RS; Gupta R

Journal

FEBS Letters, Vol. 234, No. 1, pp. 141–144

Publisher

Wiley

Publication Date

July 4, 1988

DOI

10.1016/0014-5793(88)81320-6

ISSN

0014-5793