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Diphtheria toxin resistance in human lymphoblast...
Journal article

Diphtheria toxin resistance in human lymphoblast lines

Abstract

Stable mutants (Dipr), highly resistant to diphtheria toxin have been selected from a sensitive human lymphoblast line. A second human lymphoblast line, HH-4 (and its derivative TK6-1) were found to be highly resistant to diphtheria toxin without any previous selection, suggesting the presence of the Dipr allele in the human population. The resistance of protein synthesis in extracts of mutant cells to diphtheria toxin indicates that the …

Authors

Gupta RS

Journal

Biochemical and Biophysical Research Communications, Vol. 94, No. 4, pp. 1303–1310

Publisher

Elsevier

Publication Date

June 1980

DOI

10.1016/0006-291x(80)90561-6

ISSN

0006-291X