Journal article
Genetic and biochemical characterization of mutants of CHO cells resistant to the protein synthesis inhibitor trichodermin
Abstract
Mutants resistant to the protein synthesis inhibitor trichodermin have been selected in Chinese hamster ovary (CHO) cells. The mutants vary in their stability from those which rapidly lose their resistance to others which are relatively stable after prolonged growth in nonselective medium. Protein synthesis in extracts from the latter class of mutants (Trir) is resistant to the inhibitory action of trichodermin as compared to similar extracts …
Authors
Gupta RS; Siminovitch L
Journal
Somatic Cell Genetics, Vol. 4, No. 3, pp. 355–374
Publisher
Springer Nature
Publication Date
May 1978
DOI
10.1007/bf01542848
ISSN
0098-0366