Journal article
Clinical update on the therapeutic use of clopidogrel: treatment of acute ST-segment elevation myocardial infarction (STEMI)
Abstract
The pathogenesis of ST-elevation myocardial infarction (STEMI) involves plaque disruption, platelet aggregation and intracoronary artery thrombus formation. Aspirin is the cornerstone of antiplatelet therapy in patients with STEMI, reducing the risk of recurrent myocardial infarction or death during the acute phase and long term by about one-quarter. Recent large randomized trials have demonstrated that the addition of clopidogrel to aspirin …
Authors
Tran H; Mehta SR; Eikelboom JW
Journal
Vascular Health and Risk Management, Vol. 2, No. 4, pp. 379–387
Publisher
Taylor & Francis
Publication Date
December 2006
DOI
10.2147/vhrm.s24379
ISSN
1176-6344