Journal article
Hypersensitivity to ADP of platelets from diabetic rats associated with enhanced fibrinogen binding
Abstract
Platelets from diabetic humans and animals are hypersensitive to ADP. The hypersensitivity to ADP of platelets from diabetic rats occurs independently of activation of the arachidonate pathway or release of dense granule contents. During platelet aggregation by ADP, fibrinogen binds to its receptor on platelets. We examined if the hypersensitivity to ADP of platelets from diabetic rats is associated with enhanced early binding of fibrinogen to …
Authors
WINOCOUR PD; PERRY DW; KINLOUGH‐RATHBONE RL
Journal
European Journal of Clinical Investigation, Vol. 22, No. 1, pp. 19–23
Publisher
Wiley
Publication Date
1 1992
DOI
10.1111/j.1365-2362.1992.tb01930.x
ISSN
0014-2972