Journal article
Aspirin resistance
Abstract
Aspirin resistance refers to less than expected suppression of thromboxane A(2) production by aspirin and has been reported to be independently associated with an increased risk of adverse cardiovascular events. Possible causes of aspirin resistance include poor compliance, drug interaction, inadequate aspirin dose, increase turnover of platelets, genetic polymorphisms of cyclo-oxygenase-1, and upregulation of alternate (non-platelet) pathways …
Authors
Tran HA; Anand SS; Hankey GJ; Eikelboom JW
Journal
Thrombosis Research, Vol. 120, No. 3, pp. 337–346
Publisher
Elsevier
Publication Date
January 2007
DOI
10.1016/j.thromres.2006.08.014
ISSN
0049-3848