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Real-Time PCR Assay for Rapid Detection and...
Journal article

Real-Time PCR Assay for Rapid Detection and Analysis of PfCRT Haplotypes of Chloroquine-Resistant Plasmodium falciparum Isolates from India

Abstract

Chloroquine-resistant Plasmodium falciparum (CRPF) malaria isolates in Southeast Asia and sub-Saharan Africa share the same Plasmodium falciparum chloroquine resistance transporter (PfCRT) haplotype (CVIET; amino acids 72 to 76). It is believed that CRPF malaria emerged in Southeast Asia and spread to sub-Saharan Africa via the Indian subcontinent. Based on this assumption, we hypothesized that CRPF isolates in India should possess the same …

Authors

Keen J; Farcas GA; Zhong K; Yohanna S; Dunne MW; Kain KC

Journal

Journal of Clinical Microbiology, Vol. 45, No. 9, pp. 2889–2893

Publisher

American Society for Microbiology

Publication Date

September 2007

DOI

10.1128/jcm.02291-06

ISSN

0095-1137