Biomarkers, Tumor Concept

subject area of

• BCR–ABL1 transcript doubling time as a predictor for treatment‐free remission failure after imatinib discontinuation in chronic myeloid leukaemia in chronic phase  Journal Articles
• HER2and Responsiveness of Breast Cancer to Adjuvant Chemotherapy  Journal Articles
• CD99 expression in Merkel cell carcinoma: a case series with an unusual paranuclear dot‐like staining pattern  Journal Articles
• A "tumour trifecta:" myelolipomata arising within an adrenocortical adenoma ipsilateral to a synchronous clear cell renal cell carcinoma.  Journal Articles
• A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor  Journal Articles
• A Multicenter Phase II Study of “Adjuvant” Irinotecan Following Resection of Colorectal Hepatic Metastases  Journal Articles
• A Poor Prognostic ALK Phenotype: A Review of Molecular Markers of Poor Prognosis in ALK Rearranged Nonsmall Cell Lung Cancer.  Journal Articles
• A Review of Physical Activity and Circulating miRNA Expression: Implications in Cancer Risk and Progression  Journal Articles
• A Systematic Review and Canadian Consensus Recommendations on the Use of Biomarkers in the Treatment of Non-small Cell Lung Cancer  Journal Articles
• A Systematic Review and Meta-Analysis of the Diagnostic Performance of BRAF V600E Immunohistochemistry in Thyroid Histopathology  Journal Articles
• A biological staging model for operable non-small cell lung cancer  Journal Articles
• A four gene signature of chromosome instability (CIN4) predicts for benefit from taxanes in the NCIC-CTG MA21 clinical trial  Journal Articles
• A four gene signature predicts benefit from anthracyclines: evidence from the BR9601 and MA.5 clinical trials  Journal Articles
• A high-throughput protocol for isolating cell-free circulating tumor DNA from peripheral blood.  Journal Articles
• A machine learning approach to radiogenomics of breast cancer: a study of 922 subjects and 529 DCE-MRI features  Journal Articles
• A p16-Ki-67-HMB45 immunohistochemistry scoring system as an ancillary diagnostic tool in the diagnosis of melanoma  Journal Articles
• A phase II study of SB939, a novel pan-histone deacetylase inhibitor, in patients with translocation-associated recurrent/metastatic sarcomas—NCIC-CTG IND 200  Journal Articles
• A phase II study of single-agent RO4929097, a gamma-secretase inhibitor of Notch signaling, in patients with recurrent platinum-resistant epithelial ovarian cancer: A study of the Princess Margaret, Chicago and California phase II consortia  Journal Articles
• A phase II study of sorafenib in patients with chemo-naive castration-resistant prostate cancer  Journal Articles
• A randomized, double-blind, window of opportunity trial evaluating the effects of chloroquine in breast cancer patients  Journal Articles
• A rapid in vitro methodology for simultaneous target discovery and antibody generation against functional cell subpopulations  Journal Articles
• AC133 expression in human stem cells  Journal Articles
• ATM activation is accompanied with earlier stages of prostate tumorigenesis  Journal Articles
• Aberrant Epigenetic Regulation: A Central Contributor to Lung Carcinogenesis and a New Therapeutic Target  Journal Articles
• Aberrant transcriptional and post-transcriptional regulation of SPAG5, a YAP-TAZ-TEAD downstream effector, fuels breast cancer cell proliferation  Journal Articles
• Ability of C‐reactive protein to complement multiple prognostic classifiers in men with metastatic castration resistant prostate cancer receiving docetaxel‐based chemotherapy  Journal Articles
• Adjuvant Chemotherapy Is Associated With Improved Overall Survival in Locally Advanced Rectal Cancer After Achievement of a Pathologic Complete Response to Chemoradiation  Journal Articles
• Advances in the molecular classification of pediatric brain tumors: a guide to the galaxy  Journal Articles
• Algorithms for prediction of the Oncotype DX recurrence score using clinicopathologic data: a review and comparison using an independent dataset  Journal Articles
• Altered peritumoral microRNA expression predicts head and neck cancer patients with a high risk of recurrence  Journal Articles
• American Society of Clinical Oncology Technology Assessment on the Use of Aromatase Inhibitors As Adjuvant Therapy for Postmenopausal Women With Hormone Receptor–Positive Breast Cancer: Status Report 2004  Journal Articles
• American Society of Clinical Oncology Technology Assessment on the use of aromatase inhibitors as adjuvant therapy for postmenopausal women with hormone receptor-positive breast cancer: Status report 2004  Journal Articles
• Amplification of MUC1 in prostate cancer metastasis and CRPC development  Journal Articles
• Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer  Journal Articles
• An Automated Micro-Total Immunoassay System for Measuring Cancer-Associated α2,3-linked Sialyl N-Glycan-Carrying Prostate-Specific Antigen May Improve the Accuracy of Prostate Cancer Diagnosis  Journal Articles
• An Ep-ICD Based Index Is a Marker of Aggressiveness and Poor Prognosis in Thyroid Carcinoma  Journal Articles
• An evidence-based guideline on the application of molecular testing in the diagnosis, prediction of prognosis, and selection of therapy in non-GIST soft tissue sarcomas  Journal Articles
• An international multicenter study to evaluate reproducibility of automated scoring for assessment of Ki67 in breast cancer  Journal Articles
• An international study to increase concordance in Ki67 scoring  Journal Articles
• Analysis of ductal carcinoma in situ by self-reported race reveals molecular differences related to outcome.  Journal Articles
• Analysis of human MDM4 variants in papillary thyroid carcinomas reveals new potential markers of cancer properties  Journal Articles
• Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections: an international multicentre collaboration  Conferences
• Angiogenic Histogenesis of Stromal Cells in Hemangioblastoma: Ultrastructural and Immunohistochemical Study  Conferences
• Artichoke phytocomplex modulates serum microRNAs in patients exposed to asbestos: a first step of a phase II clinical trial  Journal Articles
• Asia–Pacific consensus guidelines on gastric cancer prevention  Journal Articles
• Assessment of p53 overexpression by non‐immunohistochemical methods  Journal Articles
• Association BetweenNRASandBRAFMutational Status and Melanoma-Specific Survival Among Patients With Higher-Risk Primary Melanoma  Journal Articles
• Association between Locoregional Failure and NFE2L2/KEAP1/CUL3 Mutations in NRG/RTOG 9512: A Randomized Trial of Radiation Fractionation in T2N0 Glottic Cancer.  Journal Articles
• Association between mesothelin expression and survival outcomes in patients with triple-negative breast cancer: a protocol for a systematic review  Journal Articles
• Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3  Journal Articles
• Association of dose escalation of octreotide long‐acting release on clinical symptoms and tumor markers and response among patients with neuroendocrine tumors  Journal Articles
• Associations between insulin-like growth factors and their binding proteins and other prognostic indicators in breast cancer  Journal Articles
• Atypical presentations of intracranial dysgerminoma mimicking central nervous system inflammatory or demyelinating disease  Journal Articles
• BOB CAT: a Large-Scale Review and Delphi Consensus for Management of Barrett’s Esophagus With No Dysplasia, Indefinite for, or Low-Grade Dysplasia  Journal Articles
• BRCA2 Mutation-associated Breast Cancers Exhibit a Distinguishing Phenotype Based on Morphology and Molecular Profiles From Tissue Microarrays  Journal Articles
• Basal growth hormone concentrations in blood and the risk for prostate cancer: A case-control study  Journal Articles
• Bcl-2 is an independent prognostic factor and adds to a biological model for predicting outcome in operable non-small cell lung cancer  Journal Articles
• Biochip arrays for the discovery of a biomarker surrogate in a phase I/II study assessing a novel anti-metastasis agent  Journal Articles
• Biology and patterns of response to EGFR-inhibition in squamous cell cancers of the lung and head & neck  Journal Articles
• Biotinidase is a Novel Marker for Papillary Thyroid Cancer Aggressiveness  Journal Articles
• Breaking the biomarker code: PD-L1 expression and checkpoint inhibition in advanced NSCLC  Journal Articles
• CK8/18 expression, the basal phenotype, and family history in identifying BRCA1‐associated breast cancer in the Ontario site of the Breast Cancer Family Registry  Journal Articles
• CNS tumor with BCOR internal tandem duplication  Journal Articles
• CRISPR/RNA Aptamer System Activated by an AND Logic Gate for Biomarker-Driven Theranostics.  Journal Articles
• Canadian Multicenter Project on Standardization of Programmed Death-Ligand 1 Immunohistochemistry 22C3 Laboratory-Developed Tests for Pembrolizumab Therapy in NSCLC  Journal Articles
• Canadian Multicentric Pan-TRK (CANTRK) Immunohistochemistry Harmonization Study  Journal Articles
• Cancer Care Ontario Guideline Recommendations for Hormone Receptor Testing in Breast Cancer  Journal Articles
• Catechol estrogen quinones as initiators of breast and other human cancers: Implications for biomarkers of susceptibility and cancer prevention  Journal Articles
• Catechol estrogen quinones as initiators of breast and other human cancers: Implications for biomarkers of susceptibility and cancer prevention  Journal Articles
• Cellular and molecular pathology of medulloblastoma  Journal Articles
• Central neurocytoma represents a tumor consisting of diverse neuronal phenotypes  Journal Articles
• Challenges in Experimental Modeling of Ovarian Cancerogenesis  Journal Articles
• Characteristics of α2,3‐sialyl N‐glycosylated PSA as a biomarker for clinically significant prostate cancer in men with elevated PSA level  Journal Articles
• Characterization of Hodgkin’s Disease Derived Cell Line HDLM-2  Journal Articles
• Characterization of metastatic urothelial carcinoma via comprehensive genomic profiling of circulating tumor DNA  Journal Articles
• Characterization of sphere-propagating cells with stem-like properties from DU145 prostate cancer cells  Journal Articles
• CircRNAs: role in human diseases and potential use as biomarkers  Journal Articles
• Circulating Inflammation Markers and Risk of Epithelial Ovarian Cancer  Journal Articles
• Circulating Tumor DNA as a Predictive Biomarker for Clinical Outcomes With Margetuximab and Pembrolizumab in Pretreated HER2-Positive Gastric/ Gastroesophageal Adenocarcinoma  Journal Articles
• Circulating enterolactone and risk of endometrial cancer  Journal Articles
• Circulating miR-21-5p and miR-148a-3p as emerging non-invasive biomarkers in thymic epithelial tumors  Journal Articles
• Circulating prolactin levels and risk of epithelial ovarian cancer  Journal Articles
• Circulating soluble Fas levels and risk of ovarian cancer  Journal Articles
• Circulating tumor DNA alterations in patients with metastatic castration‐resistant prostate cancer  Journal Articles
• Clear cell papillary renal cell carcinoma as part of histologically discordant multifocal renal cell carcinoma: A case report and review of literature  Journal Articles
• Clinical Trial Evidence Supporting US Food and Drug Administration Approval of Novel Cancer Therapies Between 2000 and 2016  Journal Articles
• Clinical and morpho-molecular classifiers for prediction of hepatocellular carcinoma prognosis and recurrence after surgical resection  Journal Articles
• Clinical and toxicity predictors of response and progression to temsirolimus in women with recurrent or metastatic endometrial cancer  Journal Articles
• Clinical outcomes and prognostic biomarkers among pregnant, post-partum and nulliparous women with breast cancer: a prospective cohort study  Journal Articles
• Clinical–pathologic significance of cancer stem cell marker expression in familial breast cancers  Journal Articles
• Clinicopathological and prognostic analysis of 429 patients with intrahepatic cholangiocarcinoma.  Journal Articles
• Coexpression of epidermal growth factor receptor with related factors is associated with a poor prognosis in non-small-cell lung cancer  Journal Articles
• Combination Epigenetic Therapy Has Efficacy in Patients with Refractory Advanced Non–Small Cell Lung Cancer  Journal Articles
• Comparative evaluation of nm23 and p16 expression as biomarkers of high‐risk human papillomavirus infection and cervical intraepithelial neoplasia 2⁺ lesions of the uterine cervix  Journal Articles
• Comparing the diagnostic accuracy of five common tumour biomarkers and CA19-9 for pancreatic cancer: a protocol for a network meta-analysis of diagnostic test accuracy  Journal Articles
• Complete genomic landscape of a recurring sporadic parathyroid carcinoma  Journal Articles
• Composite analysis of immunological and metabolic markers defines novel subtypes of triple negative breast cancer  Journal Articles
• Correlation of PET-CT nodal SUVmax with p16 positivity in oropharyngeal squamous cell carcinoma  Journal Articles
• Correspondence re: Chokkalingam A. et al., Insulin-like growth factors and prostate cancer: a population-based case-control study in China. Cancer Epidemiol. Biomark. Prev., 10: 421-427, 2001.  Journal Articles
• Cost Effectiveness of EML4-ALK Fusion Testing and First-Line Crizotinib Treatment for Patients With Advanced ALK-Positive Non–Small-Cell Lung Cancer  Journal Articles
• Cotargeting Ephrin Receptor Tyrosine Kinases A2 and A3 in Cancer Stem Cells Reduces Growth of Recurrent Glioblastoma  Journal Articles
• Crinophagy in Neuroblastoma: A Case Report and Review of the Literature  Journal Articles
• Culture and Isolation of Brain Tumor Initiating Cells  Journal Articles
• Current challenges and future perspectives of radiotherapy for locally advanced breast cancer  Journal Articles
• Cyclin E expression in breast cancer: predicting germline BRCA1 mutations, prognosis and response to treatment  Journal Articles
• Cyclooxygenase-2 protein levels are independent of epidermal growth factor receptor expression or activation in operable non-small cell lung cancer  Journal Articles
• Cytogenetic Prognostication Within Medulloblastoma Subgroups  Journal Articles
• Dalteparin Low Molecular Weight Heparin (LMWH) in ovarian cancer: A phase II randomized study  Journal Articles
• Desmoplastic small round cell tumour in a 74 year old man: an uncommon cause of ascites (case report)  Journal Articles
• Development of a 90-Minute Integrated Noninvasive Urinary Assay for Bladder Cancer Detection  Journal Articles
• Development of a continuous assay for the measurement of tissue factor procoagulant activity on intact cells  Journal Articles
• Development, validation and results from the impact of treatment evolution in non-small cell lung cancer (iTEN) model  Journal Articles
• Diagnosis of Prostate Cancer  Journal Articles
• Diagnostic utility of CD56 immunohistochemistry in papillary carcinoma of the thyroid  Journal Articles
• Differential Induction of Antimicrobial REGIII by the Intestinal Microbiota and Bifidobacterium breve NCC2950  Journal Articles
• Direct Profiling of Cancer Biomarkers in Tumor Tissue Using a Multiplexed Nanostructured Microelectrode Integrated Circuit  Journal Articles
• Discordance between Immunohistochemistry and Erb-B2 Receptor Tyrosine Kinase 2 mRNA to Determine Human Epidermal Growth Factor Receptor 2 Low Status for Breast Cancer  Journal Articles
• Dynamic Bio‐Barcode Assay Enables Electrochemical Detection of a Cancer Biomarker in Undiluted Human Plasma: A Sample‐In‐Answer‐Out Approach  Journal Articles
• EMSY and CCND1 amplification in familial breast cancer: from the Ontario site of the Breast Cancer Family Registry  Journal Articles
• Economic Analysis: Randomized Placebo-Controlled Clinical Trial of Erlotinib in Advanced Non-Small Cell Lung Cancer  Journal Articles
• Editorial comment on Leung et al.: CUB and zona pellucida-like domain-containing protein 1 (CUZD1): A novel serological biomarker for ovarian cancer  Journal Articles
• Effect of Incorporation of Pretreatment Serum Carcinoembryonic Antigen Levels Into AJCC Staging for Colon Cancer on 5-Year Survival  Journal Articles
• Effect of re-irradiation for painful bone metastases on urinary markers of osteoclast activity (NCIC CTG SC.20U)  Journal Articles
• Effects of Iodine-125 Brachytherapy on the Proliferative Capacity and Histopathological Features of Glioblastoma Recurring after Initial Therapy  Journal Articles
• Elevated C‐Peptides, Abdominal Obesity, and Abnormal Adipokine Profile are Associated With Higher Gleason Scores in Prostate Cancer  Journal Articles
• Enhanced prediction of breast cancer prognosis by evaluating expression of p53 and prostate-specific antigen in combination  Journal Articles
• Enzymatic Litmus Test for Selective Colorimetric Detection of C–C Single Nucleotide Polymorphisms  Journal Articles
• Enzyme-linked immunoabsorbent assay-detected p53 protein accumulation: a prognostic factor in a large breast cancer cohort.  Conferences
• Eosinophilic vacuolated tumor (EVT) of kidney demonstrates sporadic TSC/MTOR mutations: next-generation sequencing multi-institutional study of 19 cases  Journal Articles
• Eosinophilic, Solid, and Cystic Renal Cell Carcinoma  Journal Articles
• Epithelial-Restricted Gene Profile of Primary Cultures from Human Prostate Tumors: A Molecular Approach to Predict Clinical Behavior of Prostate Cancer  Journal Articles
• Epithelial–stromal interaction increases cell proliferation, survival and tumorigenicity in a mouse model of human epithelial ovarian cancer  Journal Articles
• Erythrocyte Membrane Fatty Acids and Subsequent Breast Cancer: a Prospective Italian Study  Journal Articles
• Estrogen independent gene expression defines clinically relevant subgroups of estrogen receptor positive breast cancer  Journal Articles
• Evaluating the Feasibility of Performing Window of Opportunity Trials in Breast Cancer  Journal Articles
• Evidence for the role of matrix metalloproteinase-13 in bone resorption by giant cell tumor of bone  Journal Articles
• Ex Vivo-expanded Natural Killer Cells Derived From Long-term Cryopreserved Cord Blood are Cytotoxic Against Primary Breast Cancer Cells  Journal Articles
• Expression of Cyclooxygenase-2 in Wilms Tumor: Immunohistochemical Study Using Tissue Microarray Methodology  Conferences
• Expression of EGFR, HER-2/neu and KIT in germ cell tumours  Journal Articles
• Expression of HER2neu in Ductal Carcinoma in situ is Associated with Local Recurrence  Journal Articles
• Expression of c-erb B-2 oncogene product in persistent gestational trophoblastic disease  Journal Articles
• Expression of p27 in Residual Rectal Cancer after Preoperative Chemoradiation Predicts Long-term Outcome  Journal Articles
• Expression profiling of familial breast cancers demonstrates higher expression of FGFR2 in BRCA2-associated tumors  Journal Articles
• Extraskeletal Ewing's Sarcoma/Primitive Neuroectodermal Tumor of the Posterior Mediastinum with t(11;22)(q24;q12)  Journal Articles
• Fasting glucose is a risk factor for breast cancer: a prospective study.  Journal Articles
• Feasibility and Performance of Elastin Trichrome as a Primary Stain in Colorectal Cancer Resection Specimens  Journal Articles
• Fit-for-Purpose Ki-67 Immunohistochemistry Assays for Breast Cancer  Journal Articles
• Fluorescence in situ hybridization gene amplification analysis of EGFR and HER2 in patients with malignant salivary gland tumors treated with lapatinib  Journal Articles
• Follicular Variant Papillary Thyroid Carcinoma Arising in Struma Ovarii  Journal Articles
• Free estradiol and breast cancer risk in postmenopausal women: comparison of measured and calculated values.  Journal Articles
• GFI1 is required for RUNX1/ETO positive acute myeloid leukemia  Journal Articles
• Genome-wide host methylation profiling of anal and cervical carcinoma  Journal Articles
• Germline variation in the insulin-like growth factor pathway and risk of Barrett’s esophagus and esophageal adenocarcinoma  Journal Articles
• Growth differentiation factor 15 (GDF15) predicts relapse free and overall survival in unresected locally advanced non-small cell lung cancer treated with chemoradiotherapy.  Journal Articles
• Guanosine-induced decrease in side population of lung cancer cells: lack of correlation with ABCG2 expression.  Journal Articles
• HER2 Testing in a Population-Based Study of Patients With Metastatic Breast Cancer Treated With Trastuzumab  Journal Articles
• HPV E6 oncoproteins and nucleic acids in neck lymph node fine needle aspirates and oral samples from patients with oropharyngeal squamous cell carcinoma  Journal Articles
• Hemispheric extra-ventricular glioneurocytoma: A clinicopathological review with detailed immunohistochemical profile  Journal Articles
• High Interleukin-15 Expression Characterizes Childhood Acute Lymphoblastic Leukemia With Involvement of the CNS  Journal Articles
• High expression of N-acetyltransferase 10: a novel independent prognostic marker of worse outcome in patients with hepatocellular carcinoma.  Journal Articles
• High molecular weight adiponectin levels are inversely associated with adiposity in pediatric brain tumor survivors  Journal Articles
• High-Dose Methotrexate for Gestational Trophoblastic Disease  Journal Articles
• Human Kallikrein 14 (Klk14) Expression in Salivary Gland Tumors  Journal Articles
• Human Tissue Kallikreins: From Gene Structure to Function and Clinical Applications  Chapters
• Hypoxia‐inducible factor‐1α in non small cell lung cancer: Relation to growth factor, protease and apoptosis pathways  Journal Articles
• IGF-I, IGFBP-3 and breast cancer in young women: a pooled re-analysis of three prospective studies  Journal Articles
• IGF-I, IGFBP-3 and breast cancer in young women: a pooled re-analysis of three prospective studies.  Journal Articles
• IGFBP-3 in epithelial ovarian carcinoma and its association with clinico-pathological features and patient survival  Journal Articles
• Identification of a Low-Risk Luminal A Breast Cancer Cohort That May Not Benefit From Breast Radiotherapy  Journal Articles
• Identification of a Novel Luminal Molecular Subtype of Breast Cancer  Journal Articles
• Identification of prognostic factors in childhood T‐cell acute lymphoblastic leukemia: Results from DFCI ALL Consortium Protocols 05‐001 and 11‐001  Journal Articles
• Imatinib Mesylate in Patients With Adenoid Cystic Cancers of the Salivary Glands Expressing c-kit: A Princess Margaret Hospital Phase II Consortium Study  Journal Articles
• Imatinib for Melanomas Harboring Mutationally Activated or Amplified KIT Arising on Mucosal, Acral, and Chronically Sun-Damaged Skin  Journal Articles
• Immune checkpoint-inhibitors and chemoradiation in stage III unresectable non-small cell lung cancer  Journal Articles
• Immunoenzymatically determined pepsinogen C concentration in breast tumor cytosols: an independent favorable prognostic factor in node-positive patients.  Journal Articles
• Immunoglobulin kappa and immunoglobulin lambda are required for expression of the anti-apoptotic molecule Bcl-xL in human colorectal cancer tissue  Journal Articles
• Immunohistochemical analysis based Ep-ICD subcellular localization index (ESLI) is a novel marker for metastatic papillary thyroid microcarcinoma  Journal Articles
• Immunohistochemical localization of tyrosine receptor kinases A and B in endometriosis‐associated ovarian cancer  Journal Articles
• Immunostaining for CD34 to determine trichoepithelioma  Journal Articles
• Impact of p16 expression, nodal status, and smoking on oncologic outcomes of patients with head and neck unknown primary squamous cell carcinoma.  Journal Articles
• Implementation of Liquid Biopsy in Non-Small-Cell Lung Cancer: An Ontario Perspective.  Journal Articles
• Improved 5-Factor Prognostic Classification of Patients Receiving Salvage Systemic Therapy for Advanced Urothelial Carcinoma  Journal Articles
• Inflammatory Markers as Prognostic Factors of Recurrence in Advanced-Stage Squamous Cell Carcinoma of the Head and Neck  Journal Articles
• Interobserver Agreement for Mismatch Repair Protein Immunohistochemistry in Endometrial and Nonserous, Nonmucinous Ovarian Carcinomas  Conferences
• Interstitial Cells of Cajal as Precursors of Gastrointestinal Stromal Tumors  Journal Articles
• Intra-tumor molecular heterogeneity in breast cancer: definitions of measures and association with distant recurrence-free survival  Journal Articles
• Intracranial Suprasellar Angiolipoma  Journal Articles
• Intranodal myofibroblastoma: study of a case suggesting smooth-muscle differentiation.  Journal Articles
• Intraoperative delineation of primary brain tumors using time-resolved fluorescence spectroscopy  Journal Articles
• Intratumoral heterogeneity: pathways to treatment resistance and relapse in human glioblastoma  Journal Articles
• JAK2V617F mutation for the early diagnosis of Ph− myeloproliferative neoplasms in patients with venous thromboembolism: a meta-analysis  Journal Articles
• Kallikrein-related peptidase 10 expression in salivary gland tissues and tumours  Journal Articles
• LINC00174 is a novel prognostic factor in thymic epithelial tumors involved in cell migration and lipid metabolism  Journal Articles
• Langerhans Cell Histiocytosis Associated With Renal Cell Carcinoma Is a Neoplastic Process  Conferences
• Lapatinib or Trastuzumab Plus Taxane Therapy for Human Epidermal Growth Factor Receptor 2–Positive Advanced Breast Cancer: Final Results of NCIC CTG MA.31  Journal Articles
• Letter to the Editor: Temporal evolution of medulloblastoma subgroups  Journal Articles
• Linkage analysis of 26 Canadian breast and breast-ovarian cancer families  Journal Articles
• Liver Metastases and Immune Checkpoint Inhibitor Efficacy in Patients With Refractory Metastatic Colorectal Cancer  Journal Articles
• Location of colon cancer (right-sided versus left-sided) as a prognostic factor and a predictor of benefit from cetuximab in NCIC CO.17  Journal Articles
• Long non-coding RNAs HERH-1 and HERH-4 facilitate cyclin A2 expression and accelerate cell cycle progression in advanced hepatocellular carcinoma  Journal Articles
• Low-grade, aggressive fibrous histiocytoma of the medial canthus  Journal Articles
• Malignancies and Biosensors: A Focus on Oral Cancer Detection through Salivary Biomarkers  Journal Articles
• Malignant Melanoma with Osteoclast-Like Giant Cells: An Unusual Host Response  Journal Articles
• Markers of insulin resistance and colorectal cancer mortality.  Journal Articles
• Measurement variability of plasma β-sitosterol and campesterol, two new biomarkers for cancer prevention  Journal Articles
• Mechanism and non-mechanism based imaging biomarkers for assessing biological response to treatment in non-small cell lung cancer  Journal Articles
• MiRNA-513a-5p inhibits progesterone receptor expression and constitutes a risk factor for breast cancer: the hOrmone and Diet in the ETiology of breast cancer prospective study  Journal Articles
• MicroRNA Signature in Metastatic Colorectal Cancer Patients Treated With Anti-EGFR Monoclonal Antibodies  Journal Articles
• Molecular Classification of Endometrial Cancers Using an Integrative DNA Sequencing Panel.  Conferences
• Molecular Imaging and Precision Medicine in Lung Cancer  Journal Articles
• Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts  Journal Articles
• Multigene panels in prostate cancer risk assessment: a systematic review  Journal Articles
• Multitargeting activity of miR-24 inhibits long-term melatonin anticancer effects  Journal Articles
• Mutant p53 protein overexpression is associated with poor outcome in patients with well or moderately differentiated ovarian carcinoma  Journal Articles
• Myofibroblastic Sarcoma in Meningioma: A New Variant of “Metaplastic” Meningioma  Journal Articles
• Neuroanatomical location of lung cancer brain metastases in 234 patients with a focus on cancer subtyping and biomarkers.  Journal Articles
• Neuroblastoma and Catecholamines  Journal Articles
• Newly diagnosed type 2 diabetes may serve as a potential marker for pancreatic cancer  Journal Articles
• Novel biomarkers for risk of prostate cancer: Results from a case–control study  Journal Articles
• Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: a phase 2, multicentre, open-label, non-randomised study  Journal Articles
• Outcomes in Patients With Clinical Stage III NSGCT Who Achieve Complete Clinical Response to Chemotherapy at Extraretroperitoneal Disease Site  Journal Articles
• Overexpression of MUC1 and Genomic Alterations in Its Network Associate with Prostate Cancer Progression  Journal Articles
• PML has a predictive role in tumor cell permissiveness to interferon-sensitive oncolytic viruses  Journal Articles
• PSA declines and survival in patients with metastatic castration-resistant prostate cancer treated with enzalutamide  Journal Articles
• Patterns of adjuvant care and outcomes of elderly women with stage I breast cancer after breast-conserving surgery: a population-based analysis  Journal Articles
• Pediatric Hepatobiliary Neoplasms  Journal Articles
• Percutaneous liver biopsy: retrospective study of primary and secondary hepatic lymphoma in twenty-one patients  Journal Articles
• Pharmacokinetics, safety, activity, and biomarker analysis of palbociclib plus letrozole as first-line treatment for ER+/HER2– advanced breast cancer in Chinese women  Journal Articles
• Phase 2 Study of Erlotinib in Combination With Linsitinib (OSI-906) or Placebo in Chemotherapy-Naive Patients With Non–Small-Cell Lung Cancer and Activating Epidermal Growth Factor Receptor Mutations  Journal Articles
• Phase I/II Study of Pemetrexed With or Without ABT-751 in Advanced or Metastatic Non–Small-Cell Lung Cancer  Journal Articles
• Phase II Study of Lapatinib in Recurrent or Metastatic Epidermal Growth Factor Receptor and/or erbB2 Expressing Adenoid Cystic Carcinoma and Non–Adenoid Cystic Carcinoma Malignant Tumors of the Salivary Glands  Journal Articles
• Pheochromocytoma and paraganglioma: nimaging characteristics  Journal Articles
• Plasma arginine as a predictive biomarker for outcomes with immune checkpoint inhibition in metastatic colorectal cancer: a correlative analysis of the CCTG CO.26 trial.  Journal Articles
• Pleural Effusion Detected at CT prior to Primary Cytoreduction for Stage III or IV Ovarian Carcinoma: Effect on Survival  Journal Articles
• Population-Based Study to Determine the Health System Costs of Using the 21-Gene Assay  Journal Articles
• Potential indicators of radiosensitivity in squamous cell carcinoma of the head and neck  Journal Articles
• Prediagnostic levels of C‐peptide, IGF‐I, IGFBP ‐1, ‐2 and ‐3 and risk of endometrial cancer  Journal Articles
• Predictive Significance of an Optimized Panel for Basal-like Breast Cancer: Results from the Canadian Cancer Trials Group MA.5 and MA.12 Phase III Clinical Trials  Journal Articles
• Predictive and Pharmacodynamic Biomarker Studies in Tumor and Skin Tissue Samples of Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Treated With Erlotinib  Journal Articles
• Prevalence and frequency of circulating t(14;18)-MBR translocation carrying cells in healthy individuals  Journal Articles
• Primary Composite Angiogenic Leiomyosarcoma?Epithelioid Angiosarcoma of the Brain  Journal Articles
• Primary Cutaneous Versus Salivary Gland Origin Mucoepidermoid Carcinoma  Journal Articles
• Primary small cell carcinoma of the cecum  Journal Articles
• Primitive Neuroectodermal Tumors of the Female Genital Tract  Journal Articles
• Primitive Nonneural Granular Cell Tumor (So-called Atypical Polypoid Granular Cell Tumor). Report of 2 Cases With Immunohistochemical and Ultrastructural Correlation  Journal Articles
• Prognostic Implications of the Immunohistochemical Expression of Human Kallikreins 5, 6, 10 and 11 in Renal Cell Carcinoma  Journal Articles
• Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial  Journal Articles
• Prognostic models for newly-diagnosed chronic lymphocytic leukaemia in adults: a systematic review and meta-analysis  Journal Articles
• Prognostic value of prostate-specific antigen for women with breast cancer: a large United States cohort study.  Journal Articles
• Prognostic value of the trichorhinophalangeal syndrome-1 (TRPS-1), a GATA family transcription factor, in early-stage breast cancer  Journal Articles
• Prognosticating Role of Serum Eosinophils on Immunotherapy Efficacy in Patients with Advanced Melanoma  Journal Articles
• Progression of atypical extraventricular neurocytoma to anaplastic ganglioglioma  Journal Articles
• Proliferation of human hepatocellular carcinoma cells from surgically resected specimens under conditionally reprogrammed culture  Journal Articles
• Prospective Cost-Effectiveness Analysis of Cetuximab in Metastatic Colorectal Cancer: Evaluation of National Cancer Institute of Canada Clinical Trials Group CO.17 Trial  Journal Articles
• Prospective Evaluation of the 21-Gene Recurrence Score Assay for Breast Cancer Decision-Making in Ontario  Journal Articles
• Prospective evaluation of a novel approach for the use of a quantitative galactose oxidase–Schiff reaction in ductal fluid samples from women with breast carcinoma  Conferences
• Prostate-specific antigen is a new favorable prognostic indicator for women with breast cancer.  Journal Articles
• Psoriasin (S100A7) expression is altered during skin tumorigenesis  Journal Articles
• Quality Improvement in Colorectal Cancer in Local Health Integration Network 4 (LHIN 4) Project (QICC-L4): Integrated Knowledge Translation in a Large Geographic Region  Journal Articles
• Radioimmunodetection: technical problems and methods of improvement  Journal Articles
• Randomised, phase II, placebo-controlled, trial of fulvestrant plus vandetanib in postmenopausal women with bone only or bone predominant, hormone-receptor-positive metastatic breast cancer (MBC): the OCOG ZAMBONEY study  Journal Articles
• Randomized Phase II Trial of Seribantumab in Combination With Paclitaxel in Patients With Advanced Platinum-Resistant or -Refractory Ovarian Cancer  Journal Articles
• Randomized controlled trials in the era of molecular oncology: methodology, biomarkers, and end points  Journal Articles
• Real-World Benefit of Nivolumab in A Canadian Non-Small-Cell Lung Cancer Cohort  Journal Articles
• Recommendations from the European Commission Initiative on Breast Cancer for multigene testing to guide the use of adjuvant chemotherapy in patients with early breast cancer, hormone receptor positive, HER-2 negative  Journal Articles
• Rectal mucosal quantitative galactose oxidase-Schiff reaction as an early detection biomarker for colorectal cancer: Comparison to fecal occult stool blood test  Journal Articles
• Reduction in serum clusterin is a potential therapeutic biomarker in patients with castration‐resistant prostate cancer treated with custirsen  Journal Articles
• Regulation of the Tumor Suppressor PTEN through Exosomes: A Diagnostic Potential for Prostate Cancer  Journal Articles
• Reliability of urinary 6-sulfatoxymelatonin as a biomarker in breast cancer  Journal Articles
• Reproducibility and variability of the rectal mucosal proliferation index using proliferating cell nuclear antigen immunohistochemistry.  Journal Articles
• Responsiveness of Intrinsic Subtypes to Adjuvant Anthracycline Substitution in the NCIC.CTG MA.5 Randomized Trial  Journal Articles
• Results of a randomized phase-III trial to evaluate the efficacy of strontium-89 adjuvant to local field external beam irradiation in the management of endocrine resistant metastatic prostate cancer  Journal Articles
• Retracted: Up‐regulation of microRNA‐145 promotes differentiation by repressing OCT4 in human endometrial adenocarcinoma cells  Journal Articles
• S100A7 overexpression is a predictive marker for high risk of malignant transformation in oral dysplasia  Journal Articles
• Sclerosing Sweat-Duct Carcinoma (Malignant Syringoma) of the Upper Eyelid  Journal Articles
• Screening of carcinoma metastasis by flow cytometry: A study of 238 cases.  Journal Articles
• Secretome proteins as candidate biomarkers for aggressive thyroid carcinomas  Journal Articles
• Selecting Patients for Oncotype DX Testing Using Standard Clinicopathologic Information  Journal Articles
• Serum Fructosamine and Subsequent Breast Cancer Risk: A Nested Case-Control Study in the ORDET Prospective Cohort Study  Journal Articles
• Serum follicle-stimulating hormone and risk of epithelial ovarian cancer in postmenopausal women.  Journal Articles
• Soft tissue osteochondroma: case report and immunohistochemistry for parathyroid hormone–related protein  Journal Articles
• Solitary Fibrous Tumor of the Orbit: A Case Series  Journal Articles
• Spindle Cell Carcinoma of the Ocular Adnexa: A Case Report and Literature Review.  Journal Articles
• Spindle epithelial tumor with thymus-like elements of the thyroid: a multi-institutional case series and review of the literature  Journal Articles
• Stereotactic ablative radiotherapy for the comprehensive treatment of 4–10 oligometastatic tumors (SABR-COMET-10): study protocol for a randomized phase III trial  Journal Articles
• Systematic Review on Hormone Receptor Testing in Breast Cancer  Journal Articles
• Systematically higher Ki67 scores on core biopsy samples compared to corresponding resection specimen in breast cancer: a multi-operator and multi-institutional study  Journal Articles
• Systemic Therapy for Stage IV Non–Small-Cell Lung Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update  Journal Articles
• TLE3 is not a predictive biomarker for taxane sensitivity in the NCIC CTG MA.21 clinical trial  Journal Articles
• TRF2 and VEGF-A: an unknown relationship with prognostic impact on survival of colorectal cancer patients  Journal Articles
• Targeting prostate cancer with HTI‐286, a synthetic analog of the marine sponge product hemiasterlin  Journal Articles
• TdT expression in Merkel cell carcinoma: potential diagnostic pitfall with blastic hematological malignancies and expanded immunohistochemical analysis  Journal Articles
• Telomeres and Telomerase in Normal and Malignant Haematologic Cells  Journal Articles
• Testosterone Breakthrough Rates during Androgen Deprivation Therapy for Castration Sensitive Prostate Cancer  Journal Articles
• The Effect of Very-low-dose Warfarin on Markers of Hypercoagulation in Metastatic Breast Cancer: Results from a Randomized Trial  Journal Articles
• The Evolutionary Landscape of Localized Prostate Cancers Drives Clinical Aggression  Journal Articles
• The HER-2/neu oncogene in breast cancer: so what is new?  Journal Articles
• The Significance of Thyroid Hormone Receptors in Breast Cancer: A Hypothesis-Generating Narrative Review  Journal Articles
• The circRNA–microRNA code: emerging implications for cancer diagnosis and treatment  Journal Articles
• The cross-talk between the macro and micro-environment in precursor lesions of pancreatic cancer leads to new and promising circulating biomarkers  Journal Articles
• The diagnostic efficacy of urinary fractionated metanephrines measured by tandem mass spectrometry in detection of pheochromocytoma  Journal Articles
• The identification of human pituitary adenoma-initiating cells  Journal Articles
• The impact of knowledge transfer on the detection of venous invasion in colorectal cancer  Journal Articles
• The importance of the methodology and sample matrix when interpreting chromogranin A results  Journal Articles
• The importance of tumour marker dual reporting during method transition: PSA high-dose hook effect detected  Journal Articles
• The landscape of RNA polymerase II–associated chromatin interactions in prostate cancer  Journal Articles
• The molecular etiology of breast cancer: Evidence from biomarkers of risk  Journal Articles
• The oncogenic role of circPVT1 in head and neck squamous cell carcinoma is mediated through the mutant p53/YAP/TEAD transcription-competent complex  Journal Articles
• The pathobiology of salivary gland  Journal Articles
• The role of circulating extracellular vesicles in breast cancer classification and molecular subtyping  Journal Articles
• The vaginal spindle cell epithelioma: A case report, review of the literature and discussion of potential histogenesis  Journal Articles
• Therapy for Stage IV Non–Small-Cell Lung Cancer With Driver Alterations: ASCO and OH (CCO) Joint Guideline Update  Journal Articles
• Thyroid hormone receptor beta-1 expression in early breast cancer: a validation study  Journal Articles
• Thyroid hormone receptor α in breast cancer: prognostic and therapeutic implications  Journal Articles
• Tolerability and efficacy of docetaxel in older men with metastatic castrate-resistant prostate cancer (mCRPC) in the TAX 327 trial  Journal Articles
• Towards a biological staging model for operable non-small cell lung cancer  Journal Articles
• Transformation of Merkel cell carcinoma to ganglioneuroblastoma in intracranial metastasis  Journal Articles
• Translation of Knowledge to Practice—Improving Awareness in NSCLC Molecular Testing  Journal Articles
• Tumor factors predictive of response to hypofractionated radiotherapy in a randomized trial following breast conserving therapy  Journal Articles
• Tumor protein expression of the DNA repair gene BRCA1 and lethal prostate cancer  Journal Articles
• Tumour necrosis is an independent prognostic marker in non-small cell lung cancer: correlation with biological variables  Journal Articles
• Undifferentiated Sarcoma of the Parotid Gland With Osseous Metaplasia  Journal Articles
• Untapped "-omics": the microbial metagenome, estrobolome, and their influence on the development of breast cancer and response to treatment.  Journal Articles
• Upregulation of FAM84B during prostate cancer progression  Journal Articles
• Urinary 6-Sulfatoxymelatonin Levels and Risk of Breast Cancer in Postmenopausal Women  Journal Articles
• Urinary 6-Sulphatoxymelatonin Levels and Risk of Breast Cancer in Premenopausal Women: The ORDET Cohort  Journal Articles
• Urinary Estrogen Metabolites and Breast Cancer: A Combined Analysis of Individual Level Data  Journal Articles
• Use of Molecular Biomarkers to Quantify the Spatial Distribution of Effects of Anticancer Drugs in Solid Tumors  Journal Articles
• Use of Reverse Transcriptase Polymerase Chain Reaction for Diagnosis and Staging of Alveolar Rhabdomyosarcoma, Ewing Sarcoma Family of Tumors, and Desmoplastic Small Round Cell Tumor  Journal Articles
• Use of Truquant BR radioimmunoassay for early detection of breast cancer recurrence in patients with stage II and stage III disease.  Journal Articles
• VDR primary targets by genome-wide transcriptional profiling  Journal Articles
• Vascular Endothelial Growth Factor Concentration as a Predictive Marker: Ready for Primetime?  Journal Articles
• Venous Invasion in Colorectal Cancer  Journal Articles
• Vulvar Poroid Hidradenoma  Journal Articles
• What Can Surrogate Tissues Tell Us about the Oxidative Stress Status of the Prostate? A Hypothesis-Generating In-Vivo Study  Journal Articles
• What biomarkers (if any) for precise medicine?  Journal Articles
• Zinc presence in invasive ductal carcinoma of the breast and its correlation with oestrogen receptor status  Journal Articles
• [ ¹⁸ F]CFA as a clinically translatable probe for PET imaging of deoxycytidine kinase activity  Journal Articles
• nMET, A New Target in Recurrent Cancer  Journal Articles
• “High-grade oncocytic renal tumor”: morphologic, immunohistochemical, and molecular genetic study of 14 cases  Journal Articles