Journal article
Differential Induction of Antimicrobial REGIII by the Intestinal Microbiota and Bifidobacterium breve NCC2950
Abstract
The intestinal microbiota is a key determinant of gut homeostasis, which is achieved, in part, through regulation of antimicrobial peptide secretion. The aim of this study was to determine the efficiency by which members of the intestinal microbiota induce the antimicrobial peptide REGIII and to elucidate the underlying pathways. We showed that germfree mice have low levels of REGIII-γ in their ileum and colon compared to mice with different …
Authors
Natividad JMM; Hayes CL; Motta J-P; Jury J; Galipeau HJ; Philip V; Garcia-Rodenas CL; Kiyama H; Bercik P; Verdu EF
Journal
Applied and Environmental Microbiology, Vol. 79, No. 24, pp. 7745–7754
Publisher
American Society for Microbiology
Publication Date
December 15, 2013
DOI
10.1128/aem.02470-13
ISSN
0099-2240