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Secretome proteins as candidate biomarkers for...
Journal article

Secretome proteins as candidate biomarkers for aggressive thyroid carcinomas

Abstract

Using proteomics in tandem with bioinformatics, the secretomes of nonaggressive and aggressive thyroid carcinoma (TC) cell lines were analyzed to detect potential biomarkers for tumor aggressiveness. A panel of nine proteins, activated leukocyte cell adhesion molecule (ALCAM/CD166), tyrosine-protein kinase receptor (AXL), amyloid beta A4 protein, amyloid-like protein 2, heterogeneous nuclear ribonucleoprotein K, phosphoglycerate kinase 1, …

Authors

Chaker S; Kashat L; Voisin S; Kaur J; Kak I; MacMillan C; Ozcelik H; Siu KWM; Ralhan R; Walfish PG

Journal

Proteomics, Vol. 13, No. 5, pp. 771–787

Publisher

Wiley

Publication Date

March 2013

DOI

10.1002/pmic.201200356

ISSN

1615-9853