Dalteparin Low Molecular Weight Heparin (LMWH) in ovarian cancer: A phase II randomized study

OBJECTIVE: Low molecular weight heparin reduces the risk of venous thromboembolism (VTE) and may have antineoplastic effects by interfering with angiogenesis and with tumor growth and metastasis. A multicentre phase II randomized trial was done to evaluate the antineoplastic potential of dalteparin in ovarian cancer (OC). MATERIALS AND METHODS: Women with newly-diagnosed epithelial OC were randomized to receive standard chemotherapy (CT) and …