Journal article
Clinical–pathologic significance of cancer stem cell marker expression in familial breast cancers
Abstract
Human breast cancer cells with a CD44+/CD24−/low or ALDH1+ phenotype have been demonstrated to be enriched for cancer stem cells (CSCs) using in vitro and in vivo techniques. The aim of this study was to determine the association between CD44+/CD24−/low and ALDH1 expression with clinical–pathologic tumor characteristics, tumor molecular subtype, and survival in a well characterized collection of familial breast cancer cases. 364 familial breast …
Authors
Bane A; Viloria-Petit A; Pinnaduwage D; Mulligan AM; O’Malley FP; Andrulis IL
Journal
Breast Cancer Research and Treatment, Vol. 140, No. 1, pp. 195–205
Publisher
Springer Nature
Publication Date
July 2013
DOI
10.1007/s10549-013-2591-1
ISSN
0167-6806