Journal article
Fit-for-Purpose Ki-67 Immunohistochemistry Assays for Breast Cancer
Abstract
New therapies are being developed for breast cancer, and in this process, some "old" biomarkers are reutilized and given a new purpose. It is not always recognized that by changing a biomarker's intended use, a new biomarker assay is created. The Ki-67 biomarker is typically assessed by immunohistochemistry (IHC) to provide a proliferative index in breast cancer. Canadian laboratories assessed the analytical performance and diagnostic accuracy …
Authors
Torlakovic EE; Baniak N; Barnes PJ; Chancey K; Chen L; Cheung C; Clairefond S; Cutz J-C; Faragalla H; Gravel DH
Journal
Laboratory Investigation, Vol. 104, No. 7,
Publisher
Elsevier
Publication Date
July 2024
DOI
10.1016/j.labinv.2024.102076
ISSN
0023-6837