Journal article
HPV E6 oncoproteins and nucleic acids in neck lymph node fine needle aspirates and oral samples from patients with oropharyngeal squamous cell carcinoma
Abstract
Commercial assays measuring HPV E6 viral oncoproteins, E6/E7 mRNA or DNA were used to test neck lymph node fine needle aspirates (FNA) and oropharyngeal samples (saliva and oral swabs) from 59 Canadian patients with oropharyngeal squamous cell carcinomas (OPSCC). Overall agreements of p16 antigen staining of tumors to FNA tested for OncoE6™, Aptima HPV E6/E7 mRNA and cobas HPV DNA were 81.4% (k 0.53), 94.9% (k 0.83) and 91.1% (k 0.73) …
Authors
Chernesky M; Jang D; Schweizer J; Arias M; Doerwald-Munoz L; Gupta M; Jackson B; Archibald S; Young J; Lytwyn A
Journal
Tumour Virus Research, Vol. 6, , pp. 1–5
Publisher
Elsevier
Publication Date
12 2018
DOI
10.1016/j.pvr.2018.05.003
ISSN
2405-8521