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A Systematic Review and Meta-Analysis of the...
Journal article

A Systematic Review and Meta-Analysis of the Diagnostic Performance of BRAF V600E Immunohistochemistry in Thyroid Histopathology

Abstract

Immunohistochemistry (IHC) in evaluating thyroid surgical specimens may facilitate diagnostic and prognostic evaluation, with potential therapeutic implications. We performed a systematic review and meta-analysis examining the analytic validity of IHC in detecting BRAFV600E mutations in thyroid cancer (primary or metastatic). We screened citations from three electronic databases (until December 20, 2018), supplemented by a hand search of …

Authors

Singarayer R; Mete O; Perrier L; Thabane L; Asa SL; Van Uum S; Ezzat S; Goldstein DP; Sawka AM

Journal

Endocrine Pathology, Vol. 30, No. 3, pp. 201–218

Publisher

Springer Nature

Publication Date

September 2019

DOI

10.1007/s12022-019-09585-2

ISSN

1046-3976