Recombinant Fusion Proteins Concept

subject area of

• In Vivo Formation of Protein Based Aqueous Microcompartments  Journal Articles
• A Barbourin-albumin Fusion Protein that Is Slowly Cleared In Vivo Retains the Ability to Inhibit Platelet Aggregation In Vitro  Journal Articles
• A Double Recombinant Adenovirus Expressing the Costimulatory Molecule B7-1 (Murine) and Human IL-2 Induces Complete Tumor Regression in a Murine Breast Adenocarcinoma Model  Journal Articles
• A Novel Approach to Tumor Suppression with Microencapsulated Recombinant Cells  Journal Articles
• A comparison of methods for prediction of pharmacokinetics across factor concentrate switching in hemophilia patients  Journal Articles
• A factor XIa-activatable hirudin-albumin fusion protein reduces thrombosis in mice without promoting blood loss  Journal Articles
• A long-lasting, plasmin-activatable thrombin inhibitor aids clot lysis in vitro and does not promote bleeding in vivo  Journal Articles
• A model of inflammatory arthritis highlights a role for oncostatin M in pro-inflammatory cytokine-induced bone destruction via RANK/RANKL.  Journal Articles
• A multiprong approach to cancer gene therapy by coencapsulated cells  Journal Articles
• A phase I trial of ANG1/2-Tie2 inhibitor trebaninib (AMG386) and temsirolimus in advanced solid tumors (PJC008/NCI♯9041)  Journal Articles
• A phase II study single agent of aflibercept (VEGF Trap) in patients with recurrent or metastatic gynecologic carcinosarcomas and uterine leiomyosarcoma. A trial of the Princess Margaret Hospital, Chicago and California Cancer Phase II Consortia  Journal Articles
• A synthetic luxCDABE gene cluster optimized for expression in high-GC bacteria  Journal Articles
• A von Willebrand factor fragment containing the D′D3 domains is sufficient to stabilize coagulation factor VIII in mice  Journal Articles
• ARMMs as a versatile platform for intracellular delivery of macromolecules  Journal Articles
• Abundant expression of herpes simplex virus glycoprotein gB using an adenovirus vector  Journal Articles
• Active site labeling of the gentamicin resistance enzyme AAC(6')-APH(2") by the lipid kinase inhibitor wortmannin  Journal Articles
• Addition of a sequence from α2-antiplasmin transforms human serum albumin into a blood clot component that speeds clot lysis  Journal Articles
• Adenovirus-mediated cytokine gene transfer at tissue sites. Overexpression of IL-6 induces lymphocytic hyperplasia in the lung.  Journal Articles
• Amino acid substitutions of the P2 residue of human antithrombin that either enhance or impair function  Journal Articles
• Amphiphysin 2 (Bin1) and T-tubule biogenesis in muscle.  Journal Articles
• Amphiphysin is a component of clathrin coats formed during synaptic vesicle recycling at the lamprey giant synapse.  Journal Articles
• An Ultrasensitive Bacterial Motor Revealed by Monitoring Signaling Proteins in Single Cells  Journal Articles
• An engineered right‐handed coiled coil domain imparts extreme thermostability to the KcsA channel  Journal Articles
• Anti-Vascular Endothelial Growth Factor Therapy Regimens for Polypoidal Choroidal Vasculopathy: A Systematic Review  Journal Articles
• Anti-vascular endothelial growth factor treatment for retinal conditions: a systematic review and meta-analysis  Journal Articles
• Antigen Interaction and Heat Inactivation Expose New Epitopes on Human IgE  Journal Articles
• Assembly of Bcl-2 into microsomal and outer mitochondrial membranes  Journal Articles
• Autoregulation of the Drosophila disconnected Gene in the Developing Visual System  Journal Articles
• BCL11A represses HBG transcription in K562 cells  Journal Articles
• Bcl-2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types.  Journal Articles
• Binding Site Determinants for the LysR-Type Transcriptional Regulator PcaQ in the Legume Endosymbiont Sinorhizobium meliloti  Journal Articles
• Biologic survival.  Journal Articles
• Biomarker Changes Associated With Both Dulaglutide and Cardiovascular Events in the REWIND Randomized Controlled Trial: A Nested Case-Control Post Hoc Analysis  Journal Articles
• Canadian preference and trends survey results for anti-VEGF treatment of macular edema.  Journal Articles
• Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres  Journal Articles
• Centrosomes have a role in regulating the destruction of cyclin B in early Drosophila embryos.  Journal Articles
• Change of Conformation of the DNA-binding Domain of p53 Is the Only Key Element for Binding of and Interference with p73  Journal Articles
• Characterization of a long-acting recombinant human serum albumin-atrial natriuretic factor (ANF) expressed in Pichia pastoris  Journal Articles
• Characterization of the mouse lysosomal sialidase promoter  Journal Articles
• Chimeric Structure of the NAD(P)+- and NADP+-dependent Malic Enzymes ofRhizobium (Sinorhizobium) meliloti  Journal Articles
• Cloning and Some Novel Characteristics of Mitochondrial Hsp70 from Chinese Hamster Cells  Journal Articles
• Cloning of Human Anti-lgE Autoantibodies and Their Role in the Regulation of IgE Synthesis  Conferences
• Cold-Active Winter Rye Glucanases with Ice-Binding Capacity  Journal Articles
• Combined administration of barbourin–albumin and hirudin–albumin fusion proteins limits fibrin(ogen) deposition on the rabbit balloon-injured aorta  Journal Articles
• Community-based evaluation of etanercept in patients with rheumatoid arthritis.  Journal Articles
• Comparative Effectiveness of Sotatercept and Approved Add-On Pulmonary Arterial Hypertension Therapies: A Systematic Review and Network Meta-Analysis.  Journal Articles
• Comparative assessment of subretinal hyper-reflective material in patients treated with brolucizumab versus aflibercept in HAWK and HARRIER  Journal Articles
• Comparative pharmacokinetics of two extended half‐life FVIII concentrates (Eloctate and Adynovate) in adolescents with hemophilia A: Is there a difference?  Journal Articles
• Comparative transcriptome analysis ofAgrobacterium tumefaciensin response to plant signal salicylic acid, indole-3-acetic acid and γ-amino butyric acid reveals signalling cross-talk andAgrobacterium-plant co-evolution  Journal Articles
• Compensatory regulation of HDAC5 in muscle maintains metabolic adaptive responses and metabolism in response to energetic stress  Journal Articles
• Construction of a Double Recombinant Adenovirus Vector Expressing a Heterodimeric Cytokine:In VitroandIn VivoProduction of Biologically Active Interleukin-12  Journal Articles
• Continuous prophylaxis with recombinant factor IX Fc fusion protein and conventional recombinant factor IX products: comparisons of efficacy and weekly factor consumption  Journal Articles
• Cross-chimeric analysis of selectivity of secretin and VPAC(1) receptor activation.  Journal Articles
• Customized Viral Immunotherapy for HPV-Associated Cancer  Journal Articles
• D-TACC: a novel centrosomal protein required for normal spindle function in the early Drosophila embryo.  Journal Articles
• Delivery of human factor IX in mice by encapsulated recombinant myoblasts: a novel approach towards allogeneic gene therapy of hemophilia B  Journal Articles
• Design and baseline characteristics of participants in the Researching cardiovascular Events with a Weekly INcretin in Diabetes (REWIND) trial on the cardiovascular effects of dulaglutide  Journal Articles
• Detection of antibodies reacting with the antithetical duffy blood group antigens Fya and Fyb using recombinant fusion proteins containing the duffy extracellular domain  Journal Articles
• Determination of the Topology of the Hydrophobic Segment of Mammalian Diacylglycerol Kinase Epsilon in a Cell Membrane and Its Relationship to Predictions from Modeling  Journal Articles
• Determination of the native form of FadD, the Escherichia coli fatty acyl-CoA synthetase, and characterization of limited proteolysis by outer membrane protease OmpT  Journal Articles
• Direct comparison of two extended-half-life recombinant FVIII products: a randomized, crossover pharmacokinetic study in patients with severe hemophilia A  Journal Articles
• Direct interaction between the transcriptional activation domain of human p53 and the TATA box-binding protein.  Journal Articles
• Disparate Subcellular Localization Patterns of Pseudomonas aeruginosa Type IV Pilus ATPases Involved in Twitching Motility  Journal Articles
• Dulaglutide and Kidney Function–Related Outcomes in Type 2 Diabetes: A REWIND Post Hoc Analysis  Journal Articles
• Dulaglutide and a Composite Outcome Reflecting Atherosclerosis in the REWIND Trial: A Post Hoc Analysis  Journal Articles
• Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial  Journal Articles
• Dulaglutide and incident atrial fibrillation or flutter in patients with type 2 diabetes: A post hoc analysis from the REWIND randomized trial  Journal Articles
• Dulaglutide and renal outcomes in type 2 diabetes: an exploratory analysis of the REWIND randomised, placebo-controlled trial  Journal Articles
• Dulaglutide slows kidney disease in type 2 diabetes − Author's reply  Journal Articles
• Dystrophin isoforms Dp71 and Dp427 have distinct roles in myogenic cells  Journal Articles
• Effect of Brolucizumab and Aflibercept on the Maximum Thickness of Pigment Epithelial Detachments and Sub-Retinal Pigment Epithelium Fluid in HAWK and HARRIER.  Journal Articles
• Effect of a thrombopoietin receptor agonist on use of intravenous immune globulin in patients with immune thrombocytopenia  Journal Articles
• Effect of dulaglutide on cognitive impairment in type 2 diabetes: an exploratory analysis of the REWIND trial  Journal Articles
• Effects of genetic fusion of factor IX to albumin on in vivo clearance in mice and rabbits  Conferences
• Effects of the Once-Weekly Glucagon-Like Peptide-1 Receptor Agonist Dulaglutide on Ambulatory Blood Pressure and Heart Rate in Patients With Type 2 Diabetes Mellitus  Journal Articles
• Efficacy Outcomes in Patients Using Alefacept in the AWARE Study  Journal Articles
• Efficacy and Safety of Dulaglutide in Older Patients: A post hoc Analysis of the REWIND trial  Journal Articles
• Efficacy and Safety of Intravitreal Aflibercept Treat-and-Extend for Macular Edema in Central Retinal Vein Occlusion: the CENTERA Study  Journal Articles
• Efficacy and Safety of Intravitreal Faricimab in Neovascular Age-Related Macular Degeneration, Diabetic Macular Edema, and Retinal Vein Occlusion: A Meta-Analysis.  Journal Articles
• Efficacy and safety outcomes of dulaglutide by baseline HbA1c: A post hoc analysis of the REWIND trial  Journal Articles
• Efficacy, safety, and treatment burden of treat-and-extend versus alternative anti-VEGF regimens for nAMD: a systematic review and meta-analysis  Journal Articles
• Elbow and Noc define a family of zinc finger proteins controlling morphogenesis of specific tracheal branches  Journal Articles
• Elicitation of utility scores in Canada for immune thrombocytopenia treated with romiplostim or watch and rescue  Journal Articles
• Eltrombopag for the treatment of chronic idiopathic (immune) thrombocytopenic purpura (ITP)  Journal Articles
• Engineered human Tmpk fused with truncated cell-surface markers: versatile cell-fate control safety cassettes  Journal Articles
• Enhancement of dendritic cell tolerogenicity by genetic modification using adenoviral vectors encoding cDNA for TGFβ1  Journal Articles
• Erectile function in men with type 2 diabetes treated with dulaglutide: an exploratory analysis of the REWIND placebo-controlled randomised trial  Journal Articles
• Ermap, a gene coding for a novel erythroid specific adhesion/receptor membrane protein  Journal Articles
• Essential magnetosome proteins MamI and MamL from magnetotactic bacteria interact in mammalian cells.  Journal Articles
• Exploring potential mediators of the cardiovascular benefit of dulaglutide in type 2 diabetes patients in REWIND  Journal Articles
• Expression and spectroscopic characterization of a large fragment of the μ-opioid receptor  Journal Articles
• Expression of the HSV-2 ribonucleotide reductase subunits in adenovirus vectors or stably transformed cells: Restoration of enzymatic activity by reassociation of enzyme subunits in the absence of other HSV proteins  Journal Articles
• Extension of the circulatory half-life of recombinant ecallantide via albumin fusion without loss of anti-kallikrein activity  Journal Articles
• Factor VII Deficiency Caused by a Structural Variant N57D of the First Epidermal Growth Factor Domain  Journal Articles
• Factor VIIa gets even bigger  Journal Articles
• Factor product utilization and health outcomes in patients with haemophilia A and B on extended half‐life concentrates: A Canadian observational study of real‐world outcomes  Journal Articles
• Factors that contribute to the immmunogenicity of therapeutic recombinant human proteins  Journal Articles
• Fusion of the C-terminal triskaidecapeptide of hirudin variant 3 to alpha1-proteinase inhibitor M358R increases the serpin-mediated rate of thrombin inhibition  Journal Articles
• Fusion to Albumin as a Means to Slow the Clearance of Small Therapeutic Proteins Using the <I>Pichia pastoris</I> Expression System: A Case Study  Journal Articles
• Fusion to Albumin as a Means to Slow the Clearance of Small Therapeutic Proteins Using the Pichia pastoris Expression System  Chapters
• Fusion to Human Serum Albumin Extends the Circulatory Half-Life and Duration of Antithrombotic Action of the Kunitz Protease Inhibitor Domain of Protease Nexin 2  Journal Articles
• Generalizability of glucagon‐like peptide‐1 receptor agonist cardiovascular outcome trials to the overall type 2 diabetes population in the United States  Journal Articles
• Generalizability of results from the recent FDA-guided cardiovascular outcomes trials to a representative population with Type 2 Diabetes attending primary care clinics  Journal Articles
• Generation of experimental allergic airways inflammation in the absence of draining lymph nodes  Journal Articles
• Genetic identification of effectors downstream of Neu (ErbB-2) autophosphorylation sites in a Drosophila model  Journal Articles
• HbA1c Reduction in Dulaglutide-Treated Patients Irrespective of Duration of Diabetes, Microvascular Disease, and BMI: A Post Hoc Analysis From the REWIND Trial  Journal Articles
• Herpes simplex virus VP16 forms a complex with the virion host shutoff protein vhs  Journal Articles
• High Mobility of Bicoid Captured by Fluorescence Correlation Spectroscopy: Implication for the Rapid Establishment of Its Gradient  Journal Articles
• High adherence to prophylaxis regimens in haemophilia B patients receiving rIX‐FP: Evidence from clinical trials and real‐world practice  Journal Articles
• Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells  Journal Articles
• Humoral immune response limits gene therapy in canine MPS I [letter]  Journal Articles
• Hypophosphatasia: Canadian update on diagnosis and management  Journal Articles
• Hypophosphatasia: presentation and response to asfotase alfa  Journal Articles
• IL-12 gene therapy protects mice in lethal Klebsiella pneumonia.  Journal Articles
• INHIBITION OF THROMBIN BY HIRUDIN GENETICALLY FUSED TO WILD-TYPE OR MUTANT ANTITHROMBIN  Journal Articles
• IRR: A Novel Member of the Insulin Receptor Family  Conferences
• Identification and Functional Characterization of a Novel Nuclear Localization Signal Present in the Yeast Nab2 Poly(A)⁺ RNA Binding Protein  Journal Articles
• Identification and characterization of a small modular domain in the herpes simplex virus host shutoff protein sufficient for interaction with VP16  Journal Articles
• Identification and functional analysis ofCITED2 mutations in patients with congenital heart defects  Journal Articles
• Identification of a domain of the herpes simplex virus trans-activator Vmw65 required for protein-DNA complex formation through the use of protein A fusion proteins  Journal Articles
• Immune thrombocytopenic purpura associated with fingolimod  Journal Articles
• Immuno-gene therapy of established prostate tumors using chimeric receptor-redirected human lymphocytes.  Journal Articles
• Immunotherapies in Dermatologic Disorders  Journal Articles
• Impact of COVID-19 on a real-world treat-and-extend regimen with aflibercept for neovascular age-related macular degeneration  Journal Articles
• Import of precursor proteins into mitochondria: site of polypeptide unfolding.  Journal Articles
• Incorporation of albumin fusion proteins into fibrin clots in vitro and in vivo: comparison of different fusion motifs recognized by factor XIIIa  Journal Articles
• Indirect comparisons of efficacy and weekly factor consumption during continuous prophylaxis with recombinant factor VIII Fc fusion protein and conventional recombinant factor VIII products  Journal Articles
• Induction of an Immune Response to Transmissible Gastroenteritis Coronavirus Using Vectors with Enteric Tropism  Journal Articles
• Induction of hTERT Expression and Telomerase Activity by Estrogens in Human Ovary Epithelium Cells  Journal Articles
• Infographic: "Planet Trial: Intravitreal aflibercept monotherapy for polypoidal choroidal vasculopathy (PCV)".  Journal Articles
• Insertion of a Retrotransposon inMbpDisrupts mRNA Splicing and Myelination in a New Mutant Rat  Journal Articles
• Insulin acutely decreases hepatic fatty acid synthase activity  Journal Articles
• Interaction between oncostatin M, interleukin 1 and prostaglandin E2 in induction of IL-6 expression in human fibroblasts  Journal Articles
• Interaction of Cyclin-dependent Kinase 5 (Cdk5) and Neuronal Cdk5 Activator in Bovine Brain  Journal Articles
• Interactions between flagellar and type III secretion proteins in Chlamydia pneumoniae  Journal Articles
• Intracellular Trafficking of CD23: Differential Regulation in Humans and Mice by Both Extracellular and Intracellular Exons  Journal Articles
• Intracellular events determine the fate of antithrombin Utah  Journal Articles
• Intravenous aflibercept for treatment of recurrent symptomatic malignant ascites in patients with advanced ovarian cancer: a phase 2, randomised, double-blind, placebo-controlled study  Journal Articles
• Isolation and Characterization of XKaiso, a Transcriptional Repressor That Associates with the Catenin Xp120 in Xenopus laevis  Journal Articles
• Kaiso regulates Znf131-mediated transcriptional activation  Journal Articles
• Lengthened G1 Phase Indicates Differentiation Status in Human Embryonic Stem Cells  Journal Articles
• Lifeact cannot visualize some forms of stress-induced twisted f-actin  Journal Articles
• Lineage, migration, and morphogenesis of longitudinal glia in the Drosophila CNS as revealed by a molecular lineage marker  Journal Articles
• Linear Free Energy Relationship Analysis of Transition State Mimicry by 3-Deoxy-d-arabino-heptulosonate-7-phosphate (DAHP) Oxime, a DAHP Synthase Inhibitor and Phosphate Mimic  Journal Articles
• Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye.  Journal Articles
• Localization of dystrophin isoform Dp71 to the inner limiting membrane of the retina suggests a unique functional contribution of Dp71 in the retina  Journal Articles
• Long-acting recombinant fusion protein linking coagulation factor IX with albumin (rIX-FP) in children  Journal Articles
• Low-Temperature Increases the Yield of Biologically Active Herring Antifreeze Protein in Pichia pastoris  Journal Articles
• Mapping the Free Energy Landscape of PKA Inhibition and Activation: A Double-Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα  Journal Articles
• Mechanistic Studies on Norcoclaurine Synthase of Benzylisoquinoline Alkaloid Biosynthesis:  An Enzymatic Pictet−Spengler Reaction  Journal Articles
• MicroRNA-145 Targeted Therapy Reduces Atherosclerosis  Conferences
• Mitochondrial precursor protein. Effects of 70-kilodalton heat shock protein on polypeptide folding, aggregation, and import competence.  Journal Articles
• Molecular and functional characterization of a partial cDNA encoding a novel chicken brain melatonin receptor  Journal Articles
• Monovalent Fc receptor blockade by an anti–Fcγ receptor/albumin fusion protein ameliorates murine ITP with abrogated toxicity  Journal Articles
• Mouse NGF promoter upstream sequences do not affect gene expression in mouse fibroblasts  Journal Articles
• Multicentre, randomised clinical trial comparing intravitreal aflibercept monotherapy versus aflibercept combined with reduced-fluence photodynamic therapy (RF-PDT) for the treatment of polypoidal choroidal vasculopathy.  Journal Articles
• Murine β-galactosidase stability is not dependent on temperature or protective protein/cathepsin A  Journal Articles
• Myelin-associated glycoprotein inhibits neurite/axon growth and causes growth cone collapse  Journal Articles
• NADP+ -dependent malic enzyme of Rhizobium meliloti  Journal Articles
• NLS-dependent nuclear localization of p120ctnis necessary to relieve Kaiso-mediated transcriptional repression  Journal Articles
• Nail Psoriasis and Biologics  Journal Articles
• Nervous system modification by transplants and gene transfer  Journal Articles
• New soluble angiopoietin analog of Hepta‐ANG1 prevents pathological vascular leakage  Journal Articles
• New treatments for idiopathic thrombocytopenic purpura: rethinking old hypotheses  Journal Articles
• Novel targeted therapies for eosinophilic disorders  Journal Articles
• Novel volumetric imaging biomarkers for assessing disease activity in eyes with PCV.  Journal Articles
• Nuclear Import of Cdk/Cyclin Complexes: Identification of Distinct Mechanisms for Import of Cdk2/Cyclin E and Cdc2/Cyclin B1  Journal Articles
• Nudeocytoplasmic shuttling by protein nuclear import factors  Journal Articles
• OPTICAL COHERENCE TOMOGRAPHY FEATURES OF POLYPOIDAL LESION CLOSURE IN POLYPOIDAL CHOROIDAL VASCULOPATHY TREATED WITH AFLIBERCEPT.  Journal Articles
• Odorant stimulation enhances survival of olfactory sensory neurons via MAPK and CREB.  Journal Articles
• Orphan Nuclear Hormone Receptor RevErbα Modulates Expression from the Promoter of the Hydratase-dehydrogenase Gene by Inhibiting Peroxisome Proliferator-activated Receptor α-Dependent Transactivation  Journal Articles
• PIGMENT EPITHELIAL DETACHMENT THICKNESS AND VARIABILITY AFFECTS VISUAL OUTCOMES IN PATIENTS WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION  Journal Articles
• Phage Display of the Serpin Alpha-1 Proteinase Inhibitor Randomized at Consecutive Residues in the Reactive Centre Loop and Biopanned with or without Thrombin  Journal Articles
• Physical Interaction with Yes-associated Protein Enhances p73 Transcriptional Activity  Journal Articles
• Platelet count or bleeding as the outcome in ITP trials?  Journal Articles
• Polyomavirus large T-antigen binds the ‘pRb related’ protein p130 through sequences in conserved region 2  Journal Articles
• Positioning new treatments in the management of immune thrombocytopenia  Journal Articles
• Potent Antithrombin Activity and Delayed Clearance From the Circulation Characterize Recombinant Hirudin Genetically Fused to Albumin  Journal Articles
• Practical Understanding of Mean Percent Psoriasis Area and Severity Index Reduction for Biologics  Journal Articles
• Production of recombinant soluble human integrin alpha4beta1.  Journal Articles
• Prolonged in vivo anticoagulant activity of a hirudin–albumin fusion protein secreted from Pichia pastoris  Journal Articles
• Prolonging the circulatory half-life of C1 esterase inhibitor via albumin fusion.  Journal Articles
• Protein Mobility in the Cytoplasm of Escherichia coli  Journal Articles
• Purification and characterization of VanR and the cytosolic domain of VanS: A two-component regulatory system required for vancomycin resistance in Enterococcus faecium BM4147  Journal Articles
• Purification of Plant-Derived Antibodies through Direct Immobilization of Affinity Ligands on Cellulose  Journal Articles
• Purification of an elastin-like fusion protein by microfiltration  Journal Articles
• Purification of chimeric heavy chain monoclonal antibody EG2‐hFc using hydrophobic interaction membrane chromatography: An alternative to protein‐A affinity chromatography  Journal Articles
• RNA polymerase II-independent recruitment of SPT6L at transcription start sites in Arabidopsis  Journal Articles
• Ranibizumab vs. aflibercept for wet age-related macular degeneration: network meta-analysis to understand the value of reduced frequency dosing  Journal Articles
• Recombinant albumins containing additional peptide sequences smaller than barbourin retain the ability of barbourin-albumin to inhibit platelet aggregation  Journal Articles
• Recombinant factor VIII Fc fusion protein for first-time immune tolerance induction: final results of the verITI-8 study  Journal Articles
• Recombinant human adenoviruses containing hybrid adenovirus type 5 (Ad5)/Ad12 E1A genes: characterization of hybrid E1A proteins and analysis of transforming activity and host range  Journal Articles
• Reduction of thrombus size in murine models of thrombosis following administration of recombinant α1-proteinase inhibitor mutant proteins  Journal Articles
• Regulated expression of plant tRNA genes by the prokaryotic tet and lac repressors.  Journal Articles
• Regulation of katF and katE in Escherichia coli K-12 by weak acids  Journal Articles
• Regulation of tissue inhibitor of metalloproteinase-1 in fibroblasts and acute phase proteins in hepatocytes in vitro by mouse oncostatin M, cardiotrophin-1, and IL-6.  Journal Articles
• Role of Aspergillus niger acrA in arsenic resistance and its use as the basis for an arsenic biosensor.  Journal Articles
• RpoS-Regulated Genes ofEscherichia coliIdentified by RandomlacZFusion Mutagenesis  Journal Articles
• Same-Day Bilateral Intravitreal Anti-Vascular Endothelial Growth Factor Injections: Experience of a Large Canadian Retina Center  Journal Articles
• Second‐line treatments in children with immune thrombocytopenia: Effect on platelet count and patient‐centered outcomes  Journal Articles
• Selective Inhibition of Inward Rectifier K ⁺ Channels (Kir2.1 or Kir2.2) Abolishes Protection by Ischemic Preconditioning in Rabbit Ventricular Cardiomyocytes  Journal Articles
• Selective binding of N-acetylglucosamine to the chicken hepatic lectin.  Journal Articles
• Self-Cleavable Stimulus Responsive Tags for Protein Purification without Chromatography  Journal Articles
• Sialidase-mediated depletion of GM2 ganglioside in Tay-Sachs neuroglia cells  Journal Articles
• Similar cardiovascular outcomes in patients with diabetes and established or high risk for coronary vascular disease treated with dulaglutide with and without baseline metformin  Journal Articles
• Smad3 Null Mice Develop Airspace Enlargement and Are Resistant to TGF-β-Mediated Pulmonary Fibrosis  Journal Articles
• Smad7 Binds to Smurf2 to Form an E3 Ubiquitin Ligase that Targets the TGFβ Receptor for Degradation  Journal Articles
• Spatially controlled simultaneous patterning of multiple growth factors in three-dimensional hydrogels  Journal Articles
• Stationary Phase Expression of a Novel Escherichia coli Outer Membrane Lipoprotein and Its Relationship with Mammalian Apolipoprotein D  Journal Articles
• Structural and Functional Studies of the Pseudomonas aeruginosa Minor Pilin, PilE  Journal Articles
• Structural modifications of outer membrane vesicles to refine them as vaccine delivery vehicles  Journal Articles
• Sustained remissions of immune thrombocytopenia associated with the use of thrombopoietin receptor agonists  Journal Articles
• Switching to extended half‐life products in Canada – preliminary data  Journal Articles
• Synergistic effects of pi3k/akt on abrogation of cytokine-dependency induced by oncogenic raf  Journal Articles
• T Cells Engineered With Chimeric Antigen Receptors Targeting NKG2D Ligands Display Lethal Toxicity in Mice  Journal Articles
• TNF-alpha reduces cerebral blood volume and disrupts tissue homeostasis via an endothelin- and TNFR2-dependent pathway  Journal Articles
• Targeting of passenger protein domains to multiple intracellular membranes  Journal Articles
• The 12- and 24-Month Effects of Intravitreal Ranibizumab, Aflibercept, and Bevacizumab on Intraocular Pressure  Journal Articles
• The BH3 domain of BAD fused to the Antennapedia peptide induces apoptosis via its alpha helical structure and independent of Bcl-2  Journal Articles
• The Orphan Nuclear Hormone Receptor LXRα Interacts with the Peroxisome Proliferator-activated Receptor and Inhibits Peroxisome Proliferator Signaling  Journal Articles
• The PEA3 Ets Transcription Factor Comprises Multiple Domains That Regulate Transactivation and DNA Binding  Journal Articles
• The Transactivation Function of the Pea3 Subfamily Ets Transcription Factors Is Regulated by Sumoylation  Journal Articles
• The Transferable Tail:  Fusion of the N-Terminal Acidic Extension of Heparin Cofactor II to α₁-Proteinase Inhibitor M358R Specifically Increases the Rate of Thrombin Inhibition  Journal Articles
• The complete N-terminal extension of heparin cofactor II is required for maximal effectiveness as a thrombin exosite 1 ligand  Journal Articles
• The effect of HIV coinfection, HAART and TB treatment on cytokine/chemokine responses to Mycobacterium tuberculosis (Mtb) antigens in active TB patients and latently Mtb infected individuals  Journal Articles
• The effect of dulaglutide on stroke: an exploratory analysis of the REWIND trial  Journal Articles
• The inhibition of endocytosis affects HDL-lipid uptake mediated by the human scavenger receptor class B type I  Journal Articles
• The short heterodimer partner receptor differentially modulates peroxisome proliferator-activated receptor α-mediated transcription from the peroxisome proliferator-response elements of the genes encoding the peroxisomal β-oxidation enzymes acyl-CoA oxidase and hydratase-dehydrogenase  Journal Articles
• Three-Dimensional Spatial Patterning of Proteins in Hydrogels  Journal Articles
• Thrombopoietin Receptor Agonists in Primary Immune Thrombocytopenia  Journal Articles
• Thrombopoietin-Receptor Agonists for Primary Immune Thrombocytopenia  Journal Articles
• Total cardiovascular or fatal events in people with type 2 diabetes and cardiovascular risk factors treated with dulaglutide in the REWIND trail: a post hoc analysis  Journal Articles
• Transcriptional regulation ofsdiAby cAMP-receptor protein, LeuO, and environmental signals inSalmonella entericaserovar Typhimurium  Journal Articles
• Transgenic mice over-expressing substance P exhibit allodynia and hyperalgesia which are reversed by substance P and N-methyl-d-aspartate receptor antagonists  Journal Articles
• Tumor Protection Following Vaccination With Low Doses of Lentivirally Transduced DCs Expressing the Self-antigen erbB2  Journal Articles
• Tumor-Targeting Domains for Chimeric Antigen Receptor T Cells  Journal Articles
• Tyrosine 740 Phosphorylation of Discoidin Domain Receptor 2 by Src Stimulates Intramolecular Autophosphorylation and Shc Signaling Complex Formation  Journal Articles
• UV-enhanced reactivation of a UV-damaged reporter gene suggests transcription-coupled repair is UV-inducible in human cells  Journal Articles
• Undercarboxylation of recombinant prothrombin revealed by analysis of γ‐carboxyglutamic acid using capillary electrophoresis and laser‐induced fluorescence  Journal Articles
• Vector-Derived Expression of Recombinant Rat Interleukin-6  Journal Articles
• Viral Engineering of Chimeric Antigen Receptor Expression on Murine and Human T Lymphocytes  Journal Articles
• Visual detection method for identifying recombinant bacterial colonies.  Journal Articles