Practical Understanding of Mean Percent Psoriasis Area and Severity Index Reduction for Biologics

BACKGROUND: Psoriasis in clinical trials is often measured by the Psoriasis Area and Severity Index (PASI). This measurement is well understood by clinical trialists and many dermatologists but rarely by patients and some clinicians. Patients may not understand their chance of improvement based on a PASI-50 or PASI-75 value (50 or 75% improvement in PASI score). They would better understand a PASI average presented as the mean percent …