Journal article
Efficacy, safety, and treatment burden of treat-and-extend versus alternative anti-VEGF regimens for nAMD: a systematic review and meta-analysis
Abstract
This study aimed to compare efficacy and treatment burden of treat-and-extend (T&E) anti-VEGF against fixed and pro re nata (PRN) regimens for neovascular age-related macular degeneration (nAMD). MEDLINE, CENTRAL, and EMBASE were searched. Randomized-controlled trials and observational studies comparing T&E to PRN or fixed dosing for treatment-naïve AMD patients were included. Mean difference (MD) for visual acuity (VA) and number of injections …
Authors
Rosenberg D; Deonarain DM; Gould J; Sothivannan A; Phillips MR; Sarohia GS; Sivaprasad S; Wykoff CC; Cheung CMG; Sarraf D
Journal
Eye, Vol. 37, No. 1, pp. 6–16
Publisher
Springer Nature
Publication Date
January 2023
DOI
10.1038/s41433-022-02020-7
ISSN
0950-222X