Journal article
Kaiso regulates Znf131-mediated transcriptional activation
Abstract
Kaiso is a dual-specificity POZ-ZF transcription factor that regulates gene expression by binding to sequence-specific Kaiso binding sites (KBS) or methyl-CpG dinucleotide pairs. Kaiso was first identified as a binding partner for the epithelial cell adhesion regulator p120(ctn). The p120(ctn)/Kaiso interaction is reminiscent of the beta-catenin/TCF interaction and several studies have suggested that Kaiso is a negative regulator of the …
Authors
Donaldson NS; Nordgaard CL; Pierre CC; Kelly KF; Robinson SC; Swystun L; Henriquez R; Graham M; Daniel JM
Journal
Experimental Cell Research, Vol. 316, No. 10, pp. 1692–1705
Publisher
Elsevier
Publication Date
June 2010
DOI
10.1016/j.yexcr.2010.03.011
ISSN
0014-4827
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AnimalsBase SequenceBreast NeoplasmsCell LineCore Binding FactorsDNADNA PrimersDNA-Binding ProteinsFemaleHumansIn Vitro TechniquesMiceMolecular Sequence DataOvarian NeoplasmsProtein Interaction Domains and MotifsRecombinant Fusion ProteinsTrans-ActivatorsTranscription FactorsTranscriptional ActivationTwo-Hybrid System Techniques