Gene Transfer Techniques Concept

subject area of

• A Chronic Inflammatory Infusion Model of Peritoneal Dialysis in Rats  Academic Article
• A High-Efficiency Cre/loxP-Based System for Construction of Adenoviral Vectors  Academic Article
• A Phase I Study of Adenovirus Mediated Gene Transfer of Interleukin 2 cDNA into Metastatic Breast Cancer or Melanoma. The Toronto Hospital, Toronto, Ontario, Canada  Academic Article
• A multiprong approach to cancer gene therapy by coencapsulated cells  Academic Article
• ADENOVIRUS-MEDIATED GENE TRANSFER IN THE TRANSPLANT SETTING  Academic Article
• Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung.  Academic Article
• Adenoviral Gene Transfer of Connective Tissue Growth Factor in the Lung Induces Transient Fibrosis  Academic Article
• Adenoviral Transfer of Murine Oncostatin M Elicits Periosteal Bone Apposition in Knee Joints of Mice, Despite Synovial Inflammation and Up-Regulated Expression of Interleukin-6 and Receptor Activator of Nuclear Factor-κB Ligand  Academic Article
• Adenoviral gene transfer of bioactive TGFbeta1 to the rodent eye as a novel model for anterior subcapsular cataract.  Academic Article
• Adenoviral gene transfer of macrophage inflammatory protein-2 in rat lung.  Academic Article
• Adenoviral vector-mediated GM-CSF gene transfer improves anti-mycobacterial immunity in mice – role of regulatory T cells  Academic Article
• Adenoviral vector-mediated interleukin-10 expression in vivo: intramuscular gene transfer inhibits cytokine responses in endotoxemia  Academic Article
• Adenoviral-Mediated Gene Transfer into Bone Marrow: An Effective Surgical Technique in Rat  Academic Article
• Adenoviral-Mediated Gene Transfer of Interleukin-6 in Rat Lung Enhances Antiviral Immunoglobulin A and G Responses in Distinct Tissue Compartments  Academic Article
• Adenoviral-Mediated Gene Transfer of Lymphotactin to the Lungs of Mice and Rats Results in Infiltration and Direct Accumulation of CD4⁺, CD8⁺, and NK Cells  Academic Article
• Adenoviral-mediated Gene Transfer to Mouse Salivary Glands  Academic Article
• Adenovirus Vectors for Cytokine Gene Expression  Conference Paper
• Adenovirus vectors for high-efficiency gene transfer into mammalian cells  Academic Article
• Adenovirus-Mediated Gene Transfer of TGF-β1 to the Renal Glomeruli Leads to Proteinuria  Academic Article
• Adenovirus-Mediated Interleukin-10 Gene Transfer Inhibits Post-Transplant Fibrous Airway Obliteration in an Animal Model of Bronchiolitis Obliterans  Academic Article
• Adenovirus-Vector-Mediated Cytokine Gene Transfer to Lung Tissue  Conference Paper
• Adenovirus-mediated decorin gene transfer prevents TGF-β-induced inhibition of lung morphogenesis  Academic Article
• Adenovirus-mediated gene transfer of the proteoglycan biglycan induces fibroblastic responses in the lung.  Academic Article
• Adenovirus-mediated gene transfer of the tumor suppressor, p53, induces apoptosis in postmitotic neurons.  Academic Article
• Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons  Academic Article
• An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene  Academic Article
• An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.  Academic Article
• Assay of human stem cells by repopulation of NOD/SCID mice  Academic Article
• Biological Therapies for Atrial Fibrillation  Academic Article
• Brown Norway Chromosome 13 Confers Protection From High Salt to Consomic Dahl S Rat  Academic Article
• Budesonide Enhances Repeated Gene Transfer and Expression in the Lung with Adenoviral Vectors  Academic Article
• Cationic Liposomes for Direct Gene Transfer in Therapy of Cancer and Other Diseases  Academic Article
• Characterization of Retroviral Gene Transfer into Highly Purified Human CD34− Cells with Primitive Hematopoietic Capacity  Academic Article
• Circulating, but not local lung, IL-5 is required for the development of antigen-induced airways eosinophilia.  Academic Article
• Combination Therapy with Interleukin-2 and Wild-Type p53 Expressed by Adenoviral Vectors Potentiates Tumor Regression in a Murine Model of Breast Cancer  Academic Article
• Comparison between conventional and "clinical" assessment of experimental lung fibrosis  Academic Article
• Connective Tissue Growth Factor Is Crucial to Inducing a Profibrotic Environment in “Fibrosis-Resistant” Balb/c Mouse Lungs  Academic Article
• Delivery of Ciliary Neurotrophic Factor via Lentiviral-Mediated Transfer Protects Axotomized Retinal Ganglion Cells for an Extended Period of Time  Academic Article
• Delivery of Recombinant Gene Products to the Central Nervous System with Nonautologous Cells in Alginate Microcapsules  Academic Article
• Delivery of viral-vectored vaccines by B cells represents a novel strategy to accelerate CD8+ T-cell recall responses  Academic Article
• Dendritic Cells Transduced with an Adenoviral Vector Encoding a Model Tumor-Associated Antigen for Tumor Vaccination  Academic Article
• Development of a FLP/frt System for Generating Helper-Dependent Adenoviral Vectors  Academic Article
• Development of small alginate microcapsules for recombinant gene product delivery to the rodent brain  Academic Article
• Differences in the Fibrogenic Response after Transfer of Active Transforming Growth Factor-β1 Gene to Lungs of “Fibrosis-prone” and “Fibrosis-resistant” Mouse Strains  Academic Article
• Disruption of antigen-induced inflammatory responses in CD40 ligand knockout mice.  Academic Article
• Effects of Stuffer DNA on Transgene Expression from Helper-Dependent Adenovirus Vectors  Academic Article
• Effects of adenoviral-mediated gene transfer of interleukin-10, interleukin-4, and transforming growth factor-β on the survival of axotomized retinal ganglion cells  Academic Article
• Efficient adenovirus-mediated gene expression in malignant human plasma cells: relative lymphoid cell resistance.  Academic Article
• Enhanced Immune Response to the Melanoma Antigen gp100 Using Recombinant Adenovirus-Transduced Dendritic Cells  Academic Article
• Enhanced Interleukin-2 Gene Transfer Immunotherapy of Breast Cancer by Coexpression of B7-1 and B7-2  Academic Article
• Enhanced Protection Against Fatal Mycobacterial Infection in SCID Beige Mice by Reshaping Innate Immunity with IFN-γ Transgene  Academic Article
• Expression of a Mutation Causing Hypertrophic Cardiomyopathy Disrupts Sarcomere Assembly in Adult Feline Cardiac Myocytes  Academic Article
• Expression of exogenous wt-p53 does not affect normal hematopoiesis: implications for bone marrow purging  Academic Article
• Gene Therapy for Pulmonary Diseases  Academic Article
• Gene Transfer of Matrix Metalloproteinase-9 Induces Tumor Regression of Breast Cancer In vivo  Academic Article
• Gene Transfer of Transforming Growth Factor-β1 to the Rat Peritoneum  Academic Article
• Gene targeting in mouse embryonic stem cells with an adenoviral vector  Academic Article
• Gene transfer for cytokine functional studies in the lung: the multifunctional role of GM-CSF in pulmonary inflammation  Academic Article
• Gene transfer into hematopoietic stem cells: long-term maintenance of in vitro activated progenitors without marrow ablation.  Academic Article
• Growth plate damage, a feature of juvenile idiopathic arthritis, can be induced by adenoviral gene transfer of oncostatin M: A comparative study in gene-deficient mice  Academic Article
• HER3 targeting of adenovirus by fiber modification increases infection of breast cancer cells in vitro, but not following intratumoral injection in mice  Academic Article
• Helper virus-free HSV-1 vectors packaged both in the presence of VSV G protein and in the absence of HSV-1 glycoprotein B support gene transfer into neurons in the rat striatum  Academic Article
• Hepatic leukocyte recruitment in response to time-limited expression of TNF-α and IL-1β  Academic Article
• High Doses of a Helper-Dependent Adenoviral Vector Yield Supraphysiological Levels ofα₁-Antitrypsin with Negligible Toxicity  Academic Article
• High-efficiency Semliki Forest virus-mediated transduction in bovine adrenal chromaffin cells  Academic Article
• Human Adenovirus Vectors for Gene Transfer into Mammalian Cells  Academic Article
• IL-12 gene transfer alters gut physiology and host immunity in nematode-infected mice  Academic Article
• IL-4 gene transfer to the small bowel serosa leads to intestinal inflammation and smooth muscle hyperresponsiveness  Academic Article
• Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy  Academic Article
• Immunization with adenovirus at the large intestinal mucosa as an effective vaccination strategy against sexually transmitted viral infection  Academic Article
• In Vivo Adenoviral-Mediated Gene Transfer of Interleukin-2 in Cutaneous Plasmacytoma  Academic Article
• In vitro correction of iduronate-2-sulfatase deficiency by adenovirus-mediated gene transfer  Academic Article
• In vivo adenovirus-mediated expression of human pre-elafin, a potent neutrophil elastase inhibitor.  Academic Article
• Incomplete complementation of the DNA repair defect in cockayne syndrome cells by the denV gene from bacteriophage T4 suggests a deficiency in base excision repair  Academic Article
• Induction of Osteogenesis in Mesenchymal Stem Cells by Activated Monocytes/Macrophages Depends on Oncostatin M Signaling  Academic Article
• Induction of angiogenesis by implantation of encapsulated primary myoblasts expressing vascular endothelial growth factor  Academic Article
• Inflammation Induced by MMP-9 Enhances Tumor Regression of Experimental Breast Cancer  Academic Article
• Interleukin 10 gene transfer prevents experimental colitis in rats  Academic Article
• Interleukin-10 Gene Transfer to the Airway Regulates Allergic Mucosal Sensitization in Mice  Academic Article
• Intra-articular IL-10 gene transfer regulates the expression of collagen-induced arthritis (CIA) in the knee and ipsilateral paw  Academic Article
• Intradermal transgenic expression of granulocyte-macrophage colony-stimulating factor induces neutrophilia, epidermal hyperplasia, Langerhans' cell/macrophage accumulation, and dermal fibrosis.  Academic Article
• Intramarrow Cytokine Gene Transfer by Adenoviral Vectors in Dogs  Academic Article
• Ionizable amino lipid interactions with POPC: implications for lipid nanoparticle function  Academic Article
• Lentiviral vectors pseudotyped with minimal filovirus envelopes increased gene transfer in murine lung  Academic Article
• Local Delivery of GM-CSF Protects Mice from Lethal Pneumococcal Pneumonia  Academic Article
• Local interleukin-12 gene transfer promotes conversion of an acute arthritis to a chronic destructive arthritis  Academic Article
• Luciferase Therapeutic Microcapsules for Gene Therapy  Academic Article
• Lysyl Oxidase–Like 1 Protein Deficiency Protects Mice from Adenoviral Transforming Growth Factor-β1–induced Pulmonary Fibrosis  Academic Article
• Methods for construction of adenovirus vectors  Academic Article
• Microencapsulation — An alternative approach to gene therapy  Conference Paper
• Nervous system modification by transplants and gene transfer  Academic Article
• Non-viral transfer approaches for the gene therapy of mucopolysaccharidosis type II (Hunter syndrome)  Conference Paper
• Nonviral Gene Therapy Approaches to Hemophilia  Academic Article
• One-step preparation of gold nanovectors using folate modified polyethylenimine and their use in target-specific gene transfection  Academic Article
• Optimizing Plasmid-Based Gene Transfer for Investigating Skeletal Muscle Structure and Function  Academic Article
• Overexpression of granulocyte-macrophage colony-stimulating factor induces pulmonary granulation tissue formation and fibrosis by induction of transforming growth factor-beta 1 and myofibroblast accumulation.  Academic Article
• PHENOTYPE, FUNCTION, AND IN VIVO MIGRATION AND SURVIVAL OF ALLOGENEIC DENDRITIC CELL PROGENITORS GENETICALLY ENGINEERED TO EXPRESS TGF-??1,2  Academic Article
• Phage-Mediated Gene Therapy  Academic Article
• Production and characterization of human 293 cell lines expressing the site-specific recombinase Cre  Academic Article
• Proinflammatory properties of IL-4 in the intestinal microenvironment  Academic Article
• Prolonged Peritoneal Gene Expression Using a Helper-Dependent Adenovirus  Academic Article
• Protection from endotoxemia by adenoviral-mediated gene transfer of human bactericidal/permeability-increasing protein  Academic Article
• Proteoglycans decorin and biglycan differentially modulate TGF-β-mediated fibrotic responses in the lung  Academic Article
• Recombinant Human Adenovirus with RatMIP-2Gene Insertion Causes Prolonged PMN Recruitment to the Murine Brain  Academic Article
• Recombinant Truncated Dystrophin Minigenes: Construction, Expression, and Adenoviral Delivery  Academic Article
• Regulation of Allergic Mucosal Sensitization by Interleukin-12 Gene Transfer to the Airway  Academic Article
• Site-specific integration mediated by a hybrid adenovirus/adeno-associated virus vector  Academic Article
• Strategies to Enhance Viral Penetration of Solid Tumors  Academic Article
• Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin  Academic Article
• Sustained and therapeutic levels of human factor IX in hemophilia B mice implanted with microcapsules: key role of encapsulated cells  Academic Article
• TGF-β effects on epithelial ion transport and barrier: reduced Cl⁻secretion blocked by a p38 MAPK inhibitor  Academic Article
• The cystic fibrosis transmembrane conductance regulator attenuates the endogenous Ca 2+ activated Cl - conductance of Xenopus oocytes  Academic Article
• The efficacy of electroporated plasmid vaccines correlates with long-term antigen production in vivo  Academic Article
• The gene transfer of soluble VEGF type I receptor (Flt-1) attenuates peritoneal fibrosis formation in mice but not soluble TGF-β type II receptor gene transfer  Academic Article
• The origin of the eukaryotic cell  Academic Article
• The use of adenoviral vectors for gene therapy and gene transfer in vivo  Academic Article
• Therapeutic Arteriogenesis by Ultrasound-Mediated VEGF ₁₆₅ Plasmid Gene Delivery to Chronically Ischemic Skeletal Muscle  Academic Article
• Therapeutic Effect of Angiostatin Gene Transfer in a Murine Model of Endometriosis  Academic Article
• Therapeutic effects of interleukin-4 gene transfer in experimental inflammatory bowel disease.  Academic Article
• Therapeutic levels of human Factor VIII in mice implanted with encapsulated cells: potential for gene therapy of haemophilia A  Academic Article
• Therapeutic serum concentrations of human alpha-1-antitrypsin after adenoviral-mediated gene transfer into mouse hepatocytes.  Academic Article
• Towards gene therapy in the nervous system.  Academic Article
• Transduction of Human Bone Marrow by Adenoviral Vector  Academic Article
• Transfer of Tumor Necrosis Factor-α to Rat Lung Induces Severe Pulmonary Inflammation and Patchy Interstitial Fibrogenesis with Induction of Transforming Growth Factor-β1 and Myofibroblasts  Academic Article
• Transfer of granulocyte-macrophage colony-stimulating factor gene to rat lung induces eosinophilia, monocytosis, and fibrotic reactions.  Academic Article
• Transfer of the Active Form of Transforming Growth Factor-β1 Gene to Newborn Rat Lung Induces Changes Consistent with Bronchopulmonary Dysplasia  Academic Article
• Transforming Growth Factor-β Gene Transfer to the Lung Induces Myofibroblast Presence and Pulmonary Fibrosis  Conference Paper
• Transforming Growth Factor-β1-Mediated Neuroprotection against Excitotoxic Injuryin Vivo  Academic Article
• Transient Gene Transfer and Expression in the Lung  Academic Article
• Transient Gene Transfer of IL-12 Regulates Chemokine Expression and Disease Severity in Experimental Arthritis  Academic Article
• Transient Gene Transfer of Non-ELR Chemokines to Rodent Lung Induces Mononuclear Cell Accumulation and Activation  Academic Article
• Tricistronic viral vectors co-expressing interleukin-12 (1L-12) and CD80 (B7-1) for the immunotherapy of cancer: Preclinical studies in myeloma  Academic Article
• Tumour immunotherapy using an adenoviral vector expressing a membrane-bound mutant of murine TNFα  Academic Article
• Use of a murine secreted alkaline phosphatase as a non-immunogenic reporter gene in mice  Academic Article
• Use of helper-dependent adenoviral vectors of alternative serotypes permits repeat vector administration  Academic Article
• Viral Engineering of Chimeric Antigen Receptor Expression on Murine and Human T Lymphocytes  Academic Article
• Wild-type p53 gene expression induces granulocytic differentiation of HL-60 cells  Academic Article