Gene Transfer Techniques Concept

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• A Chronic Inflammatory Infusion Model of Peritoneal Dialysis in Rats  Journal Articles
• A High-Efficiency Cre/loxP-Based System for Construction of Adenoviral Vectors  Journal Articles
• A Phase I Study of Adenovirus Mediated Gene Transfer of Interleukin 2 cDNA into Metastatic Breast Cancer or Melanoma. The Toronto Hospital, Toronto, Ontario, Canada  Journal Articles
• A multiprong approach to cancer gene therapy by coencapsulated cells  Journal Articles
• A review of gene and stem cell therapy in cutaneous wound healing  Journal Articles
• ADENOVIRUS-MEDIATED GENE TRANSFER IN THE TRANSPLANT SETTING  Journal Articles
• Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung.  Journal Articles
• Adenoviral Gene Transfer of Connective Tissue Growth Factor in the Lung Induces Transient Fibrosis  Journal Articles
• Adenoviral Transfer of Murine Oncostatin M Elicits Periosteal Bone Apposition in Knee Joints of Mice, Despite Synovial Inflammation and Up-Regulated Expression of Interleukin-6 and Receptor Activator of Nuclear Factor-κB Ligand  Journal Articles
• Adenoviral gene transfer of bioactive TGFbeta1 to the rodent eye as a novel model for anterior subcapsular cataract.  Journal Articles
• Adenoviral gene transfer of macrophage inflammatory protein-2 in rat lung.  Journal Articles
• Adenoviral vector-mediated GM-CSF gene transfer improves anti-mycobacterial immunity in mice – role of regulatory T cells  Journal Articles
• Adenoviral vector-mediated interleukin-10 expression in vivo: intramuscular gene transfer inhibits cytokine responses in endotoxemia  Journal Articles
• Adenoviral-Mediated Gene Transfer into Bone Marrow: An Effective Surgical Technique in Rat  Journal Articles
• Adenoviral-Mediated Gene Transfer of Interleukin-6 in Rat Lung Enhances Antiviral Immunoglobulin A and G Responses in Distinct Tissue Compartments  Journal Articles
• Adenoviral-Mediated Gene Transfer of Lymphotactin to the Lungs of Mice and Rats Results in Infiltration and Direct Accumulation of CD4⁺, CD8⁺, and NK Cells  Journal Articles
• Adenoviral-mediated Gene Transfer to Mouse Salivary Glands  Journal Articles
• Adenovirus Vectors for Cytokine Gene Expression  Conferences
• Adenovirus vectors for high-efficiency gene transfer into mammalian cells  Journal Articles
• Adenovirus-Based Transient Expression Systems for Peritoneal Membrane Research  Journal Articles
• Adenovirus-Mediated Gene Transfer of TGF-β1 to the Renal Glomeruli Leads to Proteinuria  Journal Articles
• Adenovirus-Mediated Gene Transfer of the Proteoglycan Biglycan Induces Fibroblastic Responses in the Lung  Conferences
• Adenovirus-Mediated Interleukin-10 Gene Transfer Inhibits Post-Transplant Fibrous Airway Obliteration in an Animal Model of Bronchiolitis Obliterans  Journal Articles
• Adenovirus-mediated decorin gene transfer prevents TGF-β-induced inhibition of lung morphogenesis  Journal Articles
• Adenovirus-mediated gene transfer of the proteoglycan biglycan induces fibroblastic responses in the lung.  Journal Articles
• Adenovirus-mediated gene transfer of the tumor suppressor, p53, induces apoptosis in postmitotic neurons.  Journal Articles
• Adenovirus‐Vector‐Mediated Cytokine Gene Transfer to Lung Tissue^a  Conferences
• Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons  Journal Articles
• An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene  Journal Articles
• An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.  Journal Articles
• Assay of human stem cells by repopulation of NOD/SCID mice  Journal Articles
• Biodistribution and Feasibility of Non-Viral IGF-I Gene Transfers in Thermally Injured Skin  Journal Articles
• Biological Therapies for Atrial Fibrillation  Journal Articles
• Brown Norway Chromosome 13 Confers Protection From High Salt to Consomic Dahl S Rat  Journal Articles
• Brown Norway chromosome 13 confers protection from high salt to consomic Dahl S rat  Conferences
• Budesonide Enhances Repeated Gene Transfer and Expression in the Lung with Adenoviral Vectors  Journal Articles
• Characterization of Retroviral Gene Transfer into Highly Purified Human CD34− Cells with Primitive Hematopoietic Capacity  Journal Articles
• Circulating, but not local lung, IL-5 is required for the development of antigen-induced airways eosinophilia.  Journal Articles
• Combination Therapy with Interleukin-2 and Wild-Type p53 Expressed by Adenoviral Vectors Potentiates Tumor Regression in a Murine Model of Breast Cancer  Journal Articles
• Combined Gene and Stem Cell Therapy for Cutaneous Wound Healing  Journal Articles
• Comparison between conventional and "clinical" assessment of experimental lung fibrosis  Journal Articles
• Connective Tissue Growth Factor Is Crucial to Inducing a Profibrotic Environment in “Fibrosis-Resistant” Balb/c Mouse Lungs  Journal Articles
• Delivery of Ciliary Neurotrophic Factor via Lentiviral-Mediated Transfer Protects Axotomized Retinal Ganglion Cells for an Extended Period of Time  Journal Articles
• Delivery of Recombinant Gene Products to the Central Nervous System with Nonautologous Cells in Alginate Microcapsules  Journal Articles
• Delivery of viral-vectored vaccines by B cells represents a novel strategy to accelerate CD8+ T-cell recall responses  Journal Articles
• Dendritic Cells Transduced with an Adenoviral Vector Encoding a Model Tumor-Associated Antigen for Tumor Vaccination  Journal Articles
• Development of a FLP/frt System for Generating Helper-Dependent Adenoviral Vectors  Journal Articles
• Development of small alginate microcapsules for recombinant gene product delivery to the rodent brain  Journal Articles
• Differences in the Fibrogenic Response after Transfer of Active Transforming Growth Factor-β1 Gene to Lungs of “Fibrosis-prone” and “Fibrosis-resistant” Mouse Strains  Journal Articles
• Disruption of antigen-induced inflammatory responses in CD40 ligand knockout mice.  Journal Articles
• Effect of Multiple Gene Transfers of Insulinlike Growth Factor I Complementary DNA Gene Constructs in Rats After Thermal Injury  Journal Articles
• Effects of Stuffer DNA on Transgene Expression from Helper-Dependent Adenovirus Vectors  Journal Articles
• Effects of adenoviral-mediated gene transfer of interleukin-10, interleukin-4, and transforming growth factor-β on the survival of axotomized retinal ganglion cells  Journal Articles
• Efficient adenovirus-mediated gene expression in malignant human plasma cells: relative lymphoid cell resistance.  Journal Articles
• Enhanced Immune Response to the Melanoma Antigen gp100 Using Recombinant Adenovirus-Transduced Dendritic Cells  Journal Articles
• Enhanced Interleukin-2 Gene Transfer Immunotherapy of Breast Cancer by Coexpression of B7-1 and B7-2  Journal Articles
• Enhanced Protection Against Fatal Mycobacterial Infection in SCID Beige Mice by Reshaping Innate Immunity with IFN-γ Transgene  Journal Articles
• Expression of a Mutation Causing Hypertrophic Cardiomyopathy Disrupts Sarcomere Assembly in Adult Feline Cardiac Myocytes  Journal Articles
• Expression of exogenous wt-p53 does not affect normal hematopoiesis: implications for bone marrow purging  Journal Articles
• Gene Therapy for Pulmonary Diseases  Journal Articles
• Gene Transfer of Matrix Metalloproteinase-9 Induces Tumor Regression of Breast CancerIn vivo  Journal Articles
• Gene Transfer of Transforming Growth Factor-β1 to the Rat Peritoneum  Journal Articles
• Gene targeting in mouse embryonic stem cells with an adenoviral vector  Journal Articles
• Gene transfer for cytokine functional studies in the lung: the multifunctional role of GM-CSF in pulmonary inflammation  Journal Articles
• Gene transfer into hematopoietic stem cells: long-term maintenance of in vitro activated progenitors without marrow ablation.  Journal Articles
• Growth plate damage, a feature of juvenile idiopathic arthritis, can be induced by adenoviral gene transfer of oncostatin M: A comparative study in gene‐deficient mice  Journal Articles
• HER3 targeting of adenovirus by fiber modification increases infection of breast cancer cells in vitro, but not following intratumoral injection in mice  Journal Articles
• Hepatic leukocyte recruitment in response to time-limited expression of TNF-α and IL-1β  Journal Articles
• High Doses of a Helper-Dependent Adenoviral Vector Yield Supraphysiological Levels ofα₁-Antitrypsin with Negligible Toxicity  Journal Articles
• High-efficiency Semliki Forest virus-mediated transduction in bovine adrenal chromaffin cells  Journal Articles
• Human Adenovirus Vectors for Gene Transfer into Mammalian Cells  Journal Articles
• IL-12 gene transfer alters gut physiology and host immunity in nematode-infected mice  Journal Articles
• IL-4 gene transfer to the small bowel serosa leads to intestinal inflammation and smooth muscle hyperresponsiveness  Journal Articles
• Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy  Journal Articles
• Immunization with adenovirus at the large intestinal mucosa as an effective vaccination strategy against sexually transmitted viral infection  Journal Articles
• In Vivo Adenoviral-Mediated Gene Transfer of Interleukin-2 in Cutaneous Plasmacytoma  Journal Articles
• In Vivo Adenovirus-Mediated Expression of Human Pre-Elafin, a Potent Neutrophil Elastase Inhibitor  Conferences
• In vitro correction of iduronate-2-sulfatase deficiency by adenovirus-mediated gene transfer  Journal Articles
• In vivo adenovirus-mediated expression of human pre-elafin, a potent neutrophil elastase inhibitor.  Journal Articles
• In vivo gene delivery mediated by non-viral vectors for cancer therapy  Journal Articles
• Incomplete complementation of the DNA repair defect in cockayne syndrome cells by the denV gene from bacteriophage T4 suggests a deficiency in base excision repair  Journal Articles
• Induction of Osteogenesis in Mesenchymal Stem Cells by Activated Monocytes/Macrophages Depends on Oncostatin M Signaling  Journal Articles
• Induction of angiogenesis by implantation of encapsulated primary myoblasts expressing vascular endothelial growth factor  Journal Articles
• Inflammation Induced by MMP-9 Enhances Tumor Regression of Experimental Breast Cancer  Journal Articles
• Innovative developments and emerging technologies in RNA therapeutics  Journal Articles
• Interaction of exogenous liposomal insulin‐like growth factor‐I cDNA gene transfer with growth factors on collagen expression in acute wounds  Journal Articles
• Interleukin 10 gene transfer prevents experimental colitis in rats  Journal Articles
• Interleukin-10 Gene Transfer to the Airway Regulates Allergic Mucosal Sensitization in Mice  Journal Articles
• Intra-articular IL-10 gene transfer regulates the expression of collagen-induced arthritis (CIA) in the knee and ipsilateral paw  Journal Articles
• Intradermal transgenic expression of granulocyte-macrophage colony-stimulating factor induces neutrophilia, epidermal hyperplasia, Langerhans' cell/macrophage accumulation, and dermal fibrosis.  Journal Articles
• Intramarrow Cytokine Gene Transfer by Adenoviral Vectors in Dogs  Journal Articles
• Ionizable amino lipid interactions with POPC: implications for lipid nanoparticle function  Journal Articles
• Lentiviral vectors pseudotyped with minimal filovirus envelopes increased gene transfer in murine lung  Journal Articles
• Liposomal Gene Transfer of Keratinocyte Growth Factor Improves Wound Healing by Altering Growth Factor and Collagen Expression  Journal Articles
• Liposomal gene transfer of multiple genes is more effective than gene transfer of a single gene  Journal Articles
• Local Delivery of GM-CSF Protects Mice from Lethal Pneumococcal Pneumonia  Journal Articles
• Local interleukin‐12 gene transfer promotes conversion of an acute arthritis to a chronic destructive arthritis  Journal Articles
• Luciferase Therapeutic Microcapsules for Gene Therapy  Journal Articles
• Lysyl Oxidase–Like 1 Protein Deficiency Protects Mice from Adenoviral Transforming Growth Factor-β1–induced Pulmonary Fibrosis  Journal Articles
• Methods for construction of adenovirus vectors  Journal Articles
• Microencapsulation — An alternative approach to gene therapy  Conferences
• Nervous system modification by transplants and gene transfer  Journal Articles
• Non-viral liposomal keratinocyte growth factor (KGF) cDNA gene transfer improves dermal and epidermal regeneration through stimulation of epithelial and mesenchymal factors  Journal Articles
• Non-viral transfer approaches for the gene therapy of mucopolysaccharidosis type II (Hunter syndrome)  Conferences
• Nonviral Gene Therapy Approaches to Hemophilia  Journal Articles
• One-step preparation of gold nanovectors using folate modified polyethylenimine and their use in target-specific gene transfection  Journal Articles
• Optimizing Plasmid-Based Gene Transfer for Investigating Skeletal Muscle Structure and Function  Journal Articles
• Overexpression of granulocyte-macrophage colony-stimulating factor induces pulmonary granulation tissue formation and fibrosis by induction of transforming growth factor-beta 1 and myofibroblast accumulation.  Journal Articles
• PHENOTYPE, FUNCTION, AND IN VIVO MIGRATION AND SURVIVAL OF ALLOGENEIC DENDRITIC CELL PROGENITORS GENETICALLY ENGINEERED TO EXPRESS TGF-??1,2  Journal Articles
• Phage-Mediated Gene Therapy  Journal Articles
• Possibilities of Non-Viral Gene Transfer to Improve Cutaneous Wound Healing  Journal Articles
• Pre-clinical evaluation of liposomal gene transfer to improve dermal and epidermal regeneration  Journal Articles
• Production and characterization of human 293 cell lines expressing the site-specific recombinase Cre  Journal Articles
• Proinflammatory properties of IL-4 in the intestinal microenvironment  Journal Articles
• Prolonged Peritoneal Gene Expression Using a Helper-Dependent Adenovirus  Journal Articles
• Protection from endotoxemia by adenoviral-mediated gene transfer of human bactericidal/permeability-increasing protein  Journal Articles
• Proteoglycans decorin and biglycan differentially modulate TGF-β-mediated fibrotic responses in the lung  Journal Articles
• Recombinant Human Adenovirus with Rat MIP‐2 Gene Insertion Causes Prolonged PMN Recruitment to the Murine Brain  Journal Articles
• Recombinant Truncated Dystrophin Minigenes: Construction, Expression, and Adenoviral Delivery  Journal Articles
• Regulation of Allergic Mucosal Sensitization by Interleukin-12 Gene Transfer to the Airway  Journal Articles
• Site-specific integration mediated by a hybrid adenovirus/adeno-associated virus vector  Journal Articles
• Strategies to Enhance Viral Penetration of Solid Tumors  Journal Articles
• Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin  Journal Articles
• Sustained and therapeutic levels of human factor IX in hemophilia B mice implanted with microcapsules: key role of encapsulated cells  Journal Articles
• TGF-β effects on epithelial ion transport and barrier: reduced Cl⁻ secretion blocked by a p38 MAPK inhibitor  Journal Articles
• The cystic fibrosis transmembrane conductance regulator attenuates the endogenous Ca 2+ activated Cl - conductance of Xenopus oocytes  Journal Articles
• The efficacy of electroporated plasmid vaccines correlates with long-term antigen production in vivo  Journal Articles
• The gene transfer of soluble VEGF type I receptor (Flt-1) attenuates peritoneal fibrosis formation in mice but not soluble TGF-β type II receptor gene transfer  Journal Articles
• The origin of the eukaryotic cell  Journal Articles
• The structure and composition of liposomes can affect skin regeneration, morphology and growth factor expression in acute wounds  Journal Articles
• The use of adenoviral vectors for gene therapy and gene transfer in vivo  Journal Articles
• Therapeutic Arteriogenesis by Ultrasound-Mediated VEGF ₁₆₅ Plasmid Gene Delivery to Chronically Ischemic Skeletal Muscle  Journal Articles
• Therapeutic Effect of Angiostatin Gene Transfer in a Murine Model of Endometriosis  Journal Articles
• Therapeutic effects of interleukin-4 gene transfer in experimental inflammatory bowel disease.  Journal Articles
• Therapeutic levels of human Factor VIII in mice implanted with encapsulated cells: potential for gene therapy of haemophilia A  Journal Articles
• Therapeutic serum concentrations of human alpha-1-antitrypsin after adenoviral-mediated gene transfer into mouse hepatocytes.  Journal Articles
• Therapeutic success and efficacy of nonviral liposomal cDNA gene transfer to the skin in vivo is dose dependent  Journal Articles
• Towards gene therapy in the nervous system.  Journal Articles
• Transduction of Human Bone Marrow by Adenoviral Vector  Journal Articles
• Transfer of Tumor Necrosis Factor-α to Rat Lung Induces Severe Pulmonary Inflammation and Patchy Interstitial Fibrogenesis with Induction of Transforming Growth Factor-β1 and Myofibroblasts  Journal Articles
• Transfer of granulocyte-macrophage colony-stimulating factor gene to rat lung induces eosinophilia, monocytosis, and fibrotic reactions.  Journal Articles
• Transfer of the Active Form of Transforming Growth Factor-β1 Gene to Newborn Rat Lung Induces Changes Consistent with Bronchopulmonary Dysplasia  Journal Articles
• Transforming Growth Factor-β Gene Transfer to the Lung Induces Myofibroblast Presence and Pulmonary Fibrosis  Conferences
• Transforming Growth Factor-β1-Mediated Neuroprotection against Excitotoxic Injuryin Vivo  Journal Articles
• Transient Gene Transfer and Expression in the Lung  Journal Articles
• Transient Gene Transfer of IL-12 Regulates Chemokine Expression and Disease Severity in Experimental Arthritis  Journal Articles
• Transient Gene Transfer of Non-ELR Chemokines to Rodent Lung Induces Mononuclear Cell Accumulation and Activation  Journal Articles
• Tricistronic viral vectors co-expressing interleukin-12 (1L-12) and CD80 (B7-1) for the immunotherapy of cancer: Preclinical studies in myeloma  Journal Articles
• Tumour immunotherapy using an adenoviral vector expressing a membrane-bound mutant of murine TNFα  Journal Articles
• Use of a murine secreted alkaline phosphatase as a non‐immunogenic reporter gene in mice  Journal Articles
• Use of helper-dependent adenoviral vectors of alternative serotypes permits repeat vector administration  Journal Articles
• Viral Engineering of Chimeric Antigen Receptor Expression on Murine and Human T Lymphocytes  Journal Articles
• Wild-type p53 gene expression induces granulocytic differentiation of HL-60 cells  Journal Articles