Journal article
PHENOTYPE, FUNCTION, AND IN VIVO MIGRATION AND SURVIVAL OF ALLOGENEIC DENDRITIC CELL PROGENITORS GENETICALLY ENGINEERED TO EXPRESS TGF-β1,2
Abstract
BACKGROUND: Administration of donor bone marrow (BM)-derived dendritic cell (DC) progenitors (DCp) that are major histocompatibility complex (MHC) class II+ but costimulatory molecule (CD40, CD80, CD86)-deficient can prolong mouse heart allograft survival This is associated with microchimerism and inhibition of antidonor cytotoxic T lymphocyte (CTL) activity. Genetic modification of these donor antigen-presenting cells to express an …
Authors
Lee WC; Zhong C; Qian S; Wan Y; Gauldie J; Mi Z; Robbins PD; Thomson AW; Lu L
Journal
Transplantation, Vol. 66, No. 12, pp. 1810–1817
Publisher
Wolters Kluwer
Publication Date
December 1998
DOI
10.1097/00007890-199812270-00040
ISSN
0041-1337