1004 Medical Biotechnology Concept

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•   Academic Article
• "Glycerate dehydrogenase" activity in acute myocardial infarction and myocardial ischemia.  Academic Article
• A High-Efficiency Cre/loxP-Based System for Construction of Adenoviral Vectors  Academic Article
• A Mendelian Randomization-Based Approach to Identify Early and Sensitive Diagnostic Biomarkers of Disease  Academic Article
• A Multimarker approach for the prediction of evolving myocardial injury in women presenting with symptoms suggestive of acute coronary syndromes  Conference Paper
• A Novel Approach to Tumor Suppression with Microencapsulated Recombinant Cells  Academic Article
• A Patient with a Leg Rash, Pedal Edema, Renal Failure, and Thrombocytopenia  Academic Article
• A Phase I Study of Adenovirus Mediated Gene Transfer of Interleukin 2 cDNA into Metastatic Breast Cancer or Melanoma. The Toronto Hospital, Toronto, Ontario, Canada  Academic Article
• A biomarker panel for identification of acute coronary syndrome patients at risk for subsequent heart failure/death  Conference Paper
• A fast, non-invasive method for measurement of cholesterol in skin samples.  Conference Paper
• A mass spectrometry approach to identify surrogate biomarkers; for early responders to an anti-metastatic/anti-tumor investigational agent  Conference Paper
• A microwell-based galactose oxidase-Schiff's assay for Thomsen-Friedenreich antigen in diagnosis of lung cancer  Conference Paper
• A multicenter evaluation of lipid profiling with a compact analyzer (Miles Clinistat).  Academic Article
• A novel test for the measurement of skin cholesterol.  Academic Article
• A novel, non-invasive skin-stripping device and method for measurement of cholesterol in skin samples.  Conference Paper
• A radioimmunoassay for serum ferritin.  Academic Article
• A short-interval specimen collection protocol with early accurate detection of acute myocardial infarction using the sensitive AccuTnI biomarker  Conference Paper
• Acceptable Analytical Variation May Exceed High-Sensitivity Cardiac Troponin I Cutoffs in Early Rule-Out and Rule-In Acute Myocardial Infarction Algorithms  Academic Article
• Accuracy and Biological Variation of Human Serum Paraoxonase 1 Activity and Polymorphism (Q192R) by Kinetic Enzyme Assay  Academic Article
• Adenoviral Vectors Expressing Lymphotactin and Interleukin 2 or Lymphotactin and Interleukin 12 Synergize to Facilitate Tumor Regression in Murine Breast Cancer Models  Academic Article
• Adenovirus-Mediated Interleukin-10 Gene Transfer Inhibits Post-Transplant Fibrous Airway Obliteration in an Animal Model of Bronchiolitis Obliterans  Academic Article
• An Enhanced System for Construction of Adenoviral Vectors by the Two-Plasmid Rescue Method  Academic Article
• An evaluation of a new blood test for TB (M-tuberculosis) detection in patients receiving BCG (Bacillus Calmette-Guerin) therapy  Conference Paper
• An initial reaction rate assay for "glycerate dehydrogenase".  Academic Article
• Antiangiogenic Cancer Therapy with Microencapsulated Cells  Academic Article
• Applicability of the AGREE II Instrument in Evaluating the Development Process and Quality of Current National Academy of Clinical Biochemistry Guidelines  Academic Article
• Application of a quality control plan for automated chemistry using a single rule by analyte control process.  Conference Paper
• Applying proteomics to characterize the plasma protein profile correlating to hyperhomocysteinemia: Linking genomics and proteomics.  Conference Paper
• Arylsulfatase A pseudodeficiency and the dopamine receptor D4 polymorphism: Genetic risk factors for psychiatric disorders in Caucasians.  Conference Paper
• Assessing Pneumatic Tube Systems with Patient-Specific Populations and Laboratory-Derived Criteria  Academic Article
• Assessing the requirement for the six-hour interval between specimens in the American Heart Association case definition for AMI, using a highly sensitive troponin assay  Conference Paper
• Association of the FABP2 T54 Variant with Plasma Triglycerides and Insulin Resistance in a Multiethnic Population  Academic Article
• Associations between PSA and IGF-I, IGF-II, IGFBP-1, and IGFBP-3 in breast cancer.  Conference Paper
• Best Practices for Monitoring Cardiac Troponin in Detecting Myocardial Injury  Academic Article
• Biomarker case study applying the 2003 AHA case definition for AMI in epidemiology and clinical research studies with the AccuTnI marker  Conference Paper
• Biomarkers for Predicting Serious Cardiac Outcomes at 72 Hours in Patients Presenting Early after Chest Pain Onset with Symptoms of Acute Coronary Syndromes  Academic Article
• Biomedical Materials (Bristol)  Journal
• Biomedical Signal Processing and Control  Journal
• Biotechnology Journal  Journal
• CHANGES IN SERUM CARNOSINASE ACTIVITY IN PATIENTS WITH THYROID-DISEASES  Conference Paper
• COMPARISON OF LUTEINIZING-HORMONE (LH, LUTROPIN) IMMUNOREACTIVITY IN SERUM BY RIA AND TIME-RESOLVED FLUORESCENCE - FINDINGS IN SERUM FROM NORMAL-CHILDREN AND THOSE TREATED WITH LHRH ANALOGS  Conference Paper
• COMPETITIVE SOLID-PHASE ENZYME-IMMUNOASSAY FOR MELATONIN IN HUMAN AND RAT SERUM AND RAT PINEAL-GLAND  Academic Article
• Cardiac and Inflammation Biomarker Profile after Initiation of Adjuvant Trastuzumab Therapy  Academic Article
• Chromatography purification of adenoviral vectors  Conference Paper
• Clinical Chemistry  Journal
• Clinical evaluation of the Beckman Coulter AccuTnI assay for the early detection of acute myocardial infarction  Conference Paper
• Combination Therapy with Interleukin-2 and Wild-Type p53 Expressed by Adenoviral Vectors Potentiates Tumor Regression in a Murine Model of Breast Cancer  Academic Article
• Combined Immunotherapy and Antiangiogenic Therapy of Cancer with Microencapsulated Cells  Academic Article
• Community Genetics Public Health Genomics  Journal
• Comparing the World Health Organization MONICA definition for Acute Myocardial Infarction versus the ESC/ACC definition in identifying chest pain patients at increased risks  Conference Paper
• Comparison of 3 assays for the measurement of activated protein C resistance (APCR).  Conference Paper
• Comparison of ColorectAlert to fecal occult blood testing and carcinoembryonic antigen for colorectal cancer screening.  Conference Paper
• Comparison of immunofluorometry and immunohistochemistry for the detection of p53 protein in lung cancer.  Conference Paper
• Comparison of the albumin cobalt binding test for ischemia modified albumin: Field testing versus reference method  Conference Paper
• Competitive solid-phase enzyme immunoassay for melatonin in human and rat serum and rat pineal gland.  Academic Article
• Construction of a Double Recombinant Adenovirus Vector Expressing a Heterodimeric Cytokine: In Vitro and In Vivo Production of Biologically Active Interleukin-12  Academic Article
• Contrast Media and Molecular Imaging  Journal
• Correction of the Growth Defect in Dwarf Mice with Nonautologous Microencapsulated Myoblasts—An Alternate Approach to Somatic Gene Therapy  Academic Article
• Current Issues in Measurement and Reporting of Urinary Albumin Excretion  Academic Article
• Current Pharmaceutical Biotechnology  Journal
• Cytokines and cell adhesion molecules exhibit cancer specific profiles in patients with metastatic disease treated with an investigational anti-metastatic agent  Conference Paper
• DNAzymes: From Creation In Vitro to Application In Vivo  Academic Article
• Delivery of Ciliary Neurotrophic Factor via Lentiviral-Mediated Transfer Protects Axotomized Retinal Ganglion Cells for an Extended Period of Time  Academic Article
• Delivery of Recombinant Gene Product to Canines with Nonautologous Microencapsulated Cells  Academic Article
• Delivery of Recombinant Gene Products to the Central Nervous System with Nonautologous Cells in Alginate Microcapsules  Academic Article
• Delivery of Recombinant Gene Products with Microencapsulated Cells In Vivo  Academic Article
• Delivery of a Secretable Adenosine Deaminase Through Microcapsules–A Novel Approach to Somatic Gene Therapy  Academic Article
• Dendritic Cells Transduced with an Adenoviral Vector Encoding a Model Tumor-Associated Antigen for Tumor Vaccination  Academic Article
• Detection of spuriously high free thyroxine results in pediatric patients.  Conference Paper
• Determination of pepsinogen C concentration in breast tumor cytosols by a highly sensitive immunofluorometric assay and its association with ether prognostic variables.  Conference Paper
• Development of Cell Lines Capable of Complementing E1, E4, and Protein IX Defective Adenovirus Type 5 Mutants  Academic Article
• Development of a Manufacturing Process for an Oncolytic Vaccine  Conference Paper
• Diagnostic Pitfall in PCR-Based  -Thalassemia Genotyping Resulting from a (G->C) Polymorphism at Nucleotide 71 3' to the  2-Globin Gene Termination Codon  Academic Article
• Direct Intratumoral Injection of an Adenovirus Expressing Interleukin-12 Induces Regression and Long-Lasting Immunity That Is Associated with Highly Localized Expression of Interleukin-12  Academic Article
• ELISA-detected p53 protein accumulation is a prognostic factor in a large cohort of breast cancer patients.  Conference Paper
• ELISA-determined p21(WAF1) expression does not correlate with non-small cell lung cancer aggressiveness.  Conference Paper
• ETHICS AND LABORATORY MEDICINE  Academic Article
• EXPRESSION OF THE PROSTATE-SPECIFIC ANTIGEN GENE IN A PRIMARY OVARIAN-CARCINOMA  Conference Paper
• Early detection of rising patterns of troponin I, T and NT-proBNP in a chest pain emergency department cohort  Conference Paper
• Economic Considerations for Health Insurance Coverage of Emerging Genetic Tests  Academic Article
• Economic Considerations of Early Rule-In/Rule-Out Algorithms for The Diagnosis of Myocardial Infarction in The Emergency Department Using Cardiac Troponin and Glycemic Biomarkers  Academic Article
• Effect of Repeat Measurements of High-Sensitivity Cardiac Troponin on the Same Sample Using the European Society of Cardiology 0-Hour/1-Hour or 2-Hour Algorithms for Early Rule-Out and Rule-In for Myocardial Infarction  Academic Article
• Effects on rounding on quality control  Conference Paper
• Encapsulation of Recombinant Cells with a Novel Magnetized Alginate for Magnetic Resonance Imaging  Academic Article
• Encapsulation of Recombinant Cells with a Novel Magnetized Alginate for Magnetic Resonance Imaging  Academic Article
• Ethics and laboratory medicine.  Academic Article
• European Reference Networks and Guideline Development and Use: Challenges and Opportunities  Academic Article
• Evaluating albumin depletion from human serum using a ProteoSpin (TM) column  Conference Paper
• Evaluation of EuII-based positive contrast enhancement after intravenous, intraperitoneal, and subcutaneous injections  Academic Article
• Evaluation of a high sensitivity cardiac troponin I assay in an Acute Coronary Syndrome population  Conference Paper
• Evaluation of the BMC column-chromatographic method for creatine kinase isoenzyme MB.  Academic Article
• Evaluation of whole blood ketone meter for measuring low levels of BHB in fasting adults  Conference Paper
• Evaluations of the creatine kinase MB kit of Boehringer.  Academic Article
• Exon 5 of the p53 gene is a target for deletions in ovarian cancer.  Academic Article
• Exploring Bacterial Carboxylate Reductases for the Reduction of Bifunctional Carboxylic Acids  Academic Article
• Expression of Human Factor IX by Microencapsulated Recombinant Fibroblasts  Academic Article
• Frequency of prostate specific antigen mRNA expression in lung tumors.  Conference Paper
• Gene Therapy: Socioeconomic and Ethical Issues A Roundtable Discussion  Academic Article
• Gene transfection in primary stem-like cells of giant cell tumor of bone  Academic Article
• Genetic Susceptibility to West Nile Virus and Dengue  Academic Article
• Getting Closer to P-Selectin  Academic Article
• Growth Retardation—An Unexpected Outcome from Growth Hormone Gene Therapy in Normal Mice with Microencapsulated Myoblasts  Academic Article
• Helper-Dependent Adenoviral Vectors Containing Modified Fiber for Improved Transduction of Developing and Mature Muscle Cells  Academic Article
• High Doses of a Helper-Dependent Adenoviral Vector Yield Supraphysiological Levels of α1-Antitrypsin with Negligible Toxicity  Academic Article
• High-Sensitivity Cardiac Troponin I Measurement for Risk Stratification in a Stable High-Risk Population  Academic Article
• High-Sensitivity Cardiac Troponin I for Predicting Death in a Female Emergency Department Population  Academic Article
• Hospital Admission and Myocardial Injury Prevalence after the Clinical Introduction of a High-Sensitivity Cardiac Troponin I Assay  Academic Article
• Human Gene Marker/Therapy Clincal Protocols (Complete Updated Listings)  Academic Article
• Human Gene Therapy  Journal
• Human Kallikrein 4: Quantitative Study in Tissues and Evidence for Its Secretion into Biological Fluids  Academic Article
• Hydrogels with reversible chemical environments for in vitro cell culture  Academic Article
• Hyperhomocysteinemia and mutations in methylene tetrahydrofolate reductase in individuals with early coronary artery disease.  Conference Paper
• IMMUNOFLUOROMETRICALLY QUANTIFIED P53 PROTEIN AS A PROGNOSTIC INDICATOR IN OVARIAN-CARCINOMA  Conference Paper
• Identification of novel biomarkers of neuropsychiatric systemic lupus erythematosus  Conference Paper
• Immuno-Isolation in Oncology - A Mini-Review  Academic Article
• Immunoassay for serum glutamine synthetase in serum: development, reference values, and preliminary study in dementias.  Academic Article
• Impact of "change criteria" and a novel high sensitivity cardiac troponin I assay in predicting health outcomes  Conference Paper
• Impact of the evolving definition of myocardial infarction and the improved analytical sensitivity of troponin measurement on the frequency of diagnosis  Conference Paper
• Improved separation of antigen-antibody complex in RIA involving ammonium sulfate.  Academic Article
• In Vivo Transtracheal Adenovirus-Mediated Transfer of Human Interleukin-10 Gene to Donor Lungs Ameliorates Ischemia-Reperfusion Injury and Improves Early Posttransplant Graft Function in the Rat  Academic Article
• Inhibition inversion in the AACC selected method for serum cholinesterase.  Academic Article
• Intramarrow Cytokine Gene Transfer by Adenoviral Vectors in Dogs  Academic Article
• Is determination of creatine kinase-2 after electrophoretic separation accurate?  Academic Article
• Labelling dendritic cells with SPIO has implications for their subsequentin vivomigration as assessed with cellular MRI  Academic Article
• Letter: Diagnosis of heart and liver diseases.  Academic Article
• Liquid-chromatographic determination of nadolol in plasma.  Academic Article
• Local Long-Term Expression of Lentivirally Delivered IL-10 in the Lung Attenuates Obliteration of Intrapulmonary Allograft Airways  Academic Article
• Long-term survival is predicted in patients presenting with chest pain by PAPP-A measurements  Conference Paper
• Measurement of Hemoglobin A1c from Filter Papers for Population-Based Studies  Academic Article
• Measurement of Treatment Effects Requires Instruments Responsive to Change Based on the Minimal Important Difference  Academic Article
• Method validation study to evaluate the analytical performance of the STAT-Site meter for the measurement of serum Beta-Hydroxybutyrate concentration  Conference Paper
• Microfluidic Devices for Automation of Assays on Drosophila Melanogaster for Applications in Drug Discovery and Biological Studies  Academic Article
• Modeling of cell culture damage and recovery leads to increased antibody and biomass productivity in CHO cell cultures  Academic Article
• Multiple Minisequencing Screen for Seven Southeast Asian Nondeletional  -Thalassemia Mutations  Academic Article
• Mutation frequencies of cholesterol ester transfer protein (CETP) and hepatic lipase (HL) in a north American population.  Conference Paper
• Ninety-Minute vs 3-h Performance of High-Sensitivity Cardiac Troponin Assays for Predicting Hospitalization for Acute Coronary Syndrome  Academic Article
• ONLINE MEASUREMENT OF POTASSIUM IN BLOOD BY CHEMICAL-SENSITIVE FIELD-EFFECT TRANSISTORS - A PRELIMINARY-REPORT  Academic Article
• On-line measurement of potassium in blood by chemical-sensitive field-effect transistors: a preliminary report.  Academic Article
• Overinterpretation of Research Findings: Evidence of “Spin” in Systematic Reviews of Diagnostic Accuracy Studies  Academic Article
• Overview of evidence-based medicine: challenges for evidence-based laboratory medicine.  Academic Article
• P53 protein is absent from the serum of patients with lung cancer.  Conference Paper
• Pediatric critical values: pediatricians' opinions  Conference Paper
• Performance of CKMB isoforms in a population defined by the 2003 American Heart Association case definition for acute coronary heart disease  Conference Paper
• Performance of the Abbott PCx glucometer in the neonatal intensive care unit.  Conference Paper
• Persistent Delivery of Factor IX in Mice: Gene Therapy for Hemophilia Using Implantable Microcapsules  Academic Article
• Persistent Increases in Cardiac Troponin Concentrations As Measured with High-Sensitivity Assays after Acute Myocardial Infarction  Academic Article
• Population-Based Genomewide Genetic Analysis of Common Clinical Chemistry Analytes  Academic Article
• Preliminary investigation of a high sensitivity PAPP-A research assay in an Acute Coronary Syndrome population  Conference Paper
• Prenatal diagnosis of genetic disorders: trials and tribulations.  Academic Article
• Proficiency testing of hemoglobin A1c (HbA1c) in the province of Ontario, Canada.  Conference Paper
• Proficiency testing of hemoglobin A1c (HbA1c) in the province of Ontario, Canada.  Conference Paper
• Profiles of urinary volatiles from metabolic disorders characterized by unusual odors.  Academic Article
• Prognostic significance of quantitatively-analyzed p53 protein accumulation in lung carcinoma.  Conference Paper
• Prognostic use of cardiac troponin T and troponin I in patients with heart failure.  Conference Paper
• Proposed Regulatory Framework for Direct-to-Consumer Genetic Testing: Diagnostics vs Genetic Screening  Academic Article
• QUANTITATIVE-ANALYSIS OF MUTANT P53 PROTEIN IN BREAST-CARCINOMA - RELATIONSHIPS TO OTHER PROGNOSTIC FACTORS  Conference Paper
• Quantitation of urinary porphyrins by use of second-derivative spectroscopy.  Academic Article
• RAPID FORMAT ASSAY FOR THE DETECTION OF ANTISTREPTOKINASE ANTIBODY IN HUMAN BLOOD  Conference Paper
• Recent Developments in PET Instrumentation  Academic Article
• Recombinant Truncated Dystrophin Minigenes: Construction, Expression, and Adenoviral Delivery  Academic Article
• Requesting and Interpreting Urine Albumin Measurements in the Primary Health Care Setting  Academic Article
• Restoration of Vitamin C Synthesis in Transgenic Gulo−/− Mice by Helper-Dependent Adenovirus-Based Expression of Gulonolactone Oxidase  Academic Article
• Rule-In and Rule-Out of Myocardial Infarction Using Cardiac Troponin and Glycemic Biomarkers in Patients with Symptoms Suggestive of Acute Coronary Syndrome  Academic Article
• SERUM PROFILE OF MULTIPLE CARDIAC BIOCHEMICAL MARKERS IN PATIENTS PRESENTING TO THE ER WITH CHEST PAIN  Conference Paper
• Safety and Efficacy of Ex Vivo Donor Lung Adenoviral IL-10 Gene Therapy in a Large Animal Lung Transplant Survival Model  Academic Article
• Segmentation of vessels in angiograms using convolutional neural networks  Academic Article
• Serial cytokine profile in an emergency department chest pain population  Conference Paper
• Simplified Quantification of Immunohistochemical Staining Based on Measurement of Color Coordinates in a Pre-Defined Pattern  Conference Paper
• Simulation Models of Misclassification Error for Single Thresholds of High-Sensitivity Cardiac Troponin I Due to Assay Bias and Imprecision  Academic Article
• Simultaneous on-line measurement of blood K+, Ca2+, Na+, and pH with a four-function ChemFET integrated-circuit sensor.  Academic Article
• Single-Tube Multiplex-PCR Screen for Anti-3.7 and Anti-4.2  -Globin Gene Triplications  Academic Article
• Solid-phase radioimmunoassay with protein-A-bearing Staphylococcus aureus cells used to assay a protein (ferritin) and a hapten (digoxin).  Academic Article
• State of the Art for Measurement of Urine Albumin: Comparison of Routine Measurement Procedures to Isotope Dilution Tandem Mass Spectrometry  Academic Article
• Stem Cells and Cloning: Advances and Applications  Journal
• Strategies to Enhance Viral Penetration of Solid Tumors  Academic Article
• Substrate-labeled fluorescent immunoassay for ethosuximide evaluated.  Academic Article
• Summarizing Studies of Diagnostic Test Performance  Academic Article
• Superior Tissue-Specific Expression from Tyrosinase and Prostate-Specific Antigen Promoters/Enhancers in Helper-Dependent Compared with First-Generation Adenoviral Vectors  Academic Article
• Suppression of Immunological Response Against a Transgene Product Delivered from Microencapsulated Cells  Academic Article
• THE EFFECT OF STORAGE ON PLASMA SAMPLES USED IN HEPARIN ASSAYS  Conference Paper
• TIME-RESOLVED IMMUNOFLUOROMETRIC ASSAY OF P53 PROTEIN  Academic Article
• Testing for creatine kinase and creatine kinase-2 in Ontario: reference ranges and assay types.  Academic Article
• The Ordering Patterns of Serological Tests in the Diagnosis of Celiac Disease  Conference Paper
• The Preventive Potential of Common, Easily Measured Risk Factors for Cardiovascular Disease  Academic Article
• The serum S100B concentration is age dependent  Academic Article
• The serum S100B concentration is age dependent.  Academic Article
• The utility of Troponin T to the diagnosis of silent myocardial infarction in patients submitted to noncardiac surgery - preliminary results of the VISION Study  Conference Paper
• Thermodynamic aspects of some radioassays.  Academic Article
• Time-resolved immunofluorometric assay of p53 protein.  Academic Article
• Transduction of Human Bone Marrow by Adenoviral Vector  Academic Article
• Transfer of Interleukin-4 and Interleukin-10 in Patients with Severe Inflammatory Bowel Disease of the Rectum  Academic Article
• Transplantation of Monocytes: A Novel Strategy for In Vivo Augmentation of Collateral Vessel Growth  Academic Article
• Treatment of a Lysosomal Storage Disease, Mucopolysaccharidosis VII, with Microencapsulated Recombinant Cells  Academic Article
• Use of a Liver-Specific Promoter Reduces Immune Response to the Transgene in Adenoviral Vectors  Academic Article
• Use of a competitive inhibitor in a kinetic enzymatic method for measuring ethanol in serum.  Academic Article
• Use of a programmable calculator in processing and interpreting serum cholinesterase phenotypes.  Academic Article
• Use of skin cholesterol to monitor response to cholesterol-lowering therapy.  Conference Paper
• Vesicular Stomatitis Virus: A Potential Therapeutic Virus for the Treatment of Hematologic Malignancy  Academic Article
• Why measure total lactate dehydrogenase activity?  Academic Article