Genetic Susceptibility to West Nile Virus and Dengue Journal Articles

abstract

• This article focuses on the host genetic predisposition to 2 viruses, West Nile virus and dengue virus, which belong to the genus <i>Flavivirus</i>. Although by definition these viruses have shared characteristics (e.g. similar size, single stranded, RNA viruses, both transmitted by the bite from an infected mosquito), they differ greatly in epidemiology and clinical manifestations. The text below not only summarizes the genetic factors that predispose to complications of these 2 important flaviviruses, but also illustrates the challenges in determining the genomic basis for complications to these viruses.

authors

• Loeb, Mark

status

• published 

publication date

• 2013

has subject area

• 1004 Medical Biotechnology (FoR)
• 1103 Clinical Sciences (FoR)
• 1117 Public Health and Health Services (FoR)
• Alleles (MeSH)
• Animals (MeSH)
• Dengue (MeSH)
• Dengue Virus (MeSH)
• Genetic Predisposition to Disease (MeSH)
• Genetics & Heredity (Science Metrix)
• Genome-Wide Association Study (MeSH)
• Genomics (MeSH)
• HLA Antigens (MeSH)
• Homozygote (MeSH)
• Humans (MeSH)
• Mice (MeSH)
• Polymorphism, Genetic (MeSH)
• West Nile Fever (MeSH)
• West Nile virus (MeSH)

published in

• Public health genomics  Journal

keywords

• Alleles
• Animals
• Dengue
• Dengue Virus
• Genetic Predisposition to Disease
• Genome-Wide Association Study
• Genomics
• HLA Antigens
• Homozygote
• Humans
• Mice
• Polymorphism, Genetic
• West Nile Fever
• West Nile virus

Digital Object Identifier (DOI)

• 10.1159/000345934

PubMed ID

• 23548711

start page

• 4

end page

• 8

volume

• 16

issue

• 1-2