Prenatal Diagnosis of Genetic Disorders: Trials and Tribulations Journal Articles

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abstract

Abstract Prenatal detection of genetic disorders by amniocentesis in the second trimester of pregnancy, followed by studies of amniotic fluid cells, has added a new dimension to genetic counseling. This paper reviews the technique, indications, results, and complications, with emphasis on the problem of interpretation of results, particularly in the detection of fetuses with metabolic diseases.

authors

Davidson, Ronald Garry
Rattazzi, Mario C

status

published

publication date

March 1, 1972

has subject area

1004 Medical Biotechnology (FoR)
1101 Medical Biochemistry and Metabolomics (FoR)
1103 Clinical Sciences (FoR)
Abortion, Spontaneous (MeSH)
Amniocentesis (MeSH)
Amnion (MeSH)
Blood Group Incompatibility (MeSH)
Cells, Cultured (MeSH)
Chromosome Aberrations (MeSH)
Chromosome Disorders (MeSH)
Culture Techniques (MeSH)
Cystic Fibrosis (MeSH)
Diagnostic Errors (MeSH)
Diffuse Cerebral Sclerosis of Schilder (MeSH)
Down Syndrome (MeSH)
Female (MeSH)
Fetal Diseases (MeSH)
Fetus (MeSH)
General Clinical Medicine (Science Metrix)
Hemorrhage (MeSH)
Humans (MeSH)
Karyotyping (MeSH)
Lipidoses (MeSH)
Metabolism, Inborn Errors (MeSH)
Pregnancy (MeSH)
Pregnancy, Multiple (MeSH)
Punctures (MeSH)
Rh-Hr Blood-Group System (MeSH)
Sex Determination Analysis (MeSH)
Time Factors (MeSH)

published in

Clinical Chemistry Journal