Journal article
Human embryonic stem cells: lessons from stem cell niches invivo
Abstract
In vivo the stem cell niche is an essential component in controlling and maintaining the stem cells' ability to survive and respond to injury. Human embryonic stem cells (hESCs) appear to be an exception to this rule as they can be removed from their blastocytic microenvironment and maintained indefinitely in vitro. However, recent observations reveal the existence of an autonomously derived in vitro hESC niche. This provides a previously …
Authors
Bendall SC; Stewart MH; Bhatia M
Journal
Regenerative Medicine, Vol. 3, No. 3, pp. 365–376
Publisher
Taylor & Francis
Publication Date
May 2008
DOI
10.2217/17460751.3.3.365
ISSN
1746-0751