Journal article
Assessing the Requirement for the 6-Hour Interval between Specimens in the American Heart Association Classification of Myocardial Infarction in Epidemiology and Clinical Research Studies
Abstract
BACKGROUND: The American Heart Association (AHA) case definition for acute myocardial infarction (AMI) requires an "adequate set" of biomarkers: 2 measurements of the same marker at least 6 h apart. A sensitive troponin assay might detect significant changes in concentration earlier. We determined AMI prevalence, using protocols with shorter intervals between measurements, with and without incorporating the time from onset of symptoms.
METHODS: …
Authors
MacRae AR; Kavsak PA; Lustig V; Bhargava R; Vandersluis R; Palomaki GE; Yerna M-J; Jaffe AS
Journal
Clinical Chemistry, Vol. 52, No. 5, pp. 812–818
Publisher
Oxford University Press (OUP)
Publication Date
May 1, 2006
DOI
10.1373/clinchem.2005.059550
ISSN
0009-9147