Further investigation of 3D dose verification in proton therapy utilizing acoustic signal, wavelet decomposition and machine learning

Online dose verification in proton therapy is a critical task for quality assurance. We further studied the feasibility of using a wavelet-based machine learning framework to accomplishing that goal in three dimensions, built upon our previous work in 1D. The wavelet decomposition was utilized to extract features of acoustic signals and a bidirectional long-short-term memory (Bi-LSTM) recurrent neural network (RNN) was used. The 3D dose …