Modified Pisano Method for Estimating Urinary Metanephrines Journal Articles

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abstract

Abstract The Pisano method [Clin. Chim. Acta 5, 406 (1960)] for estimating urinary metanephrine, used in the screening of hypertensive persons for pheochromocytoma, has been modified by replacing ion-exchange chromatography with differential solvent extraction. An internal standard is incorporated to correct for procedural losses. Interference from some related compounds is negligible. Normal-range values obtained for various age groups by the present method compare well with those obtained by Pisano’s procedure, but are higher than values reported for more specific methods.

authors

Gupta, Ram
Price, D
Keane, PM

status

published

publication date

June 1, 1973

has subject area

1004 Medical Biotechnology (FoR)
1101 Medical Biochemistry and Metabolomics (FoR)
1103 Clinical Sciences (FoR)
Adolescent (MeSH)
Adult (MeSH)
Age Factors (MeSH)
Catecholamines (MeSH)
Child (MeSH)
Child, Preschool (MeSH)
Chromatography, Ion Exchange (MeSH)
Creatinine (MeSH)
Ethanolamines (MeSH)
Flavoring Agents (MeSH)
General Clinical Medicine (Science Metrix)
Humans (MeSH)
Hydrogen-Ion Concentration (MeSH)
Hypertension (MeSH)
Infant (MeSH)
Infant, Newborn (MeSH)
Mass Screening (MeSH)
Methods (MeSH)
Methoxyhydroxyphenylglycol (MeSH)
Neuroblastoma (MeSH)
Oxidation-Reduction (MeSH)
Phenethylamines (MeSH)
Pheochromocytoma (MeSH)
Solubility (MeSH)
Spectrophotometry, Ultraviolet (MeSH)
Vanilmandelic Acid (MeSH)

published in

Clinical Chemistry Journal