Educational Recommendations on Selected Analytical and Clinical Aspects of Natriuretic Peptides with a Focus on Heart Failure: A Report from the IFCC Committee on Clinical Applications of Cardiac Bio-Markers Journal Articles uri icon

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  • Abstract The IFCC Committee on Clinical Applications of Cardiac Bio-Markers (C-CB) has directives and initiatives focused on providing evidence-based educational resources to aid and improve understanding around key analytical and clinical aspects of cardiac biomarkers used in clinical practice and the research setting. As a task force, we have previously published position statements and recommendations focused on use and analytical aspects of high-sensitivity cardiac troponin assays. The current educational document is the first from the C-CB highlighting important biochemical, analytical, and clinical aspects as they relate to the natriuretic peptides (NPs), including B-type natriuretic peptide (BNP) and N-terminal pro–B-type natriuretic peptide (NT-proBNP), with a focus on heart failure.


  • Kavsak, Peter
  • Lam, Carolyn SP
  • Saenger, Amy K
  • Jaffe, Allan S
  • Collinson, Paul
  • Pulkki, Kari
  • Omland, Tobjørn
  • Lefèvre, Guillaume
  • Body, Richard
  • Ordonez-Llanos, Jordi
  • Apple, Fred S

publication date

  • October 1, 2019