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Reference Interval Harmonization: Harnessing the...
Journal article

Reference Interval Harmonization: Harnessing the Power of Big Data Analytics to Derive Common Reference Intervals across Populations and Testing Platforms

Abstract

BACKGROUND: Harmonization in laboratory medicine is essential for consistent and accurate clinical decision-making. There is significant and unwarranted variation in reference intervals (RIs) used by laboratories for assays with established analytical traceability. The Canadian Society of Clinical Chemists (CSCC) Working Group on Reference Interval Harmonization (hRI-WG) aims to establish harmonized RIs (hRIs) for laboratory tests and support …

Authors

Bohn MK; Bailey D; Balion C; Cembrowski G; Collier C; De Guire V; Higgins V; Jung B; Ali ZM; Seccombe D

Journal

Clinical Chemistry, Vol. 69, No. 9, pp. 991–1008

Publisher

Oxford University Press (OUP)

Publication Date

September 1, 2023

DOI

10.1093/clinchem/hvad099

ISSN

0009-9147