Journal article
Association of Chromosome 9p21 with Subsequent Coronary Heart Disease Events: A GENIUS-CHD Study of Individual Participant Data
Abstract
BACKGROUND: Genetic variation at chromosome 9p21 is a recognized risk factor for coronary heart disease (CHD). However, its effect on disease progression and subsequent events is unclear, raising questions about its value for stratification of residual risk.
METHODS: A variant at chromosome 9p21 (rs1333049) was tested for association with subsequent events during follow-up in 103 357 Europeans with established CHD at baseline from the …
Authors
Patel RS; Schmidt AF; Tragante V; McCubrey RO; Holmes MV; Howe LJ; Direk K; Åkerblom A; Leander K; Virani SS
Journal
Circulation Genomic and Precision Medicine, Vol. 12, No. 4, pp. e002471–e002471
Publisher
Wolters Kluwer
Publication Date
4 2019
DOI
10.1161/circgen.119.002471
ISSN
1942-325X