selected scholarly activity
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chapters
- Phosphorus Reagents for Two‐, Three‐, and Four‐Carbon Homologation of Carbonyl Compounds to Functionalized Olefins. 401-427. 2023
- Chapter 4 Human induced pluripotent stem cells for modeling of herpes simplex virus 1 infections. 69-93. 2021
- Human induced pluripotent stem cells for modeling of herpes simplex virus 1 infections. 69-93. 2021
- Chapter 3 Synthetic Approaches to the Naturally Occurring Anticancer Amaryllidaceae Alkaloids trans-dihydrolycoricidine and trans-dihydronarciclasine. Studies in Natural Products Chemistry. 85-108. 2017
- Stereoselective preparation of stilbenes employing trialkylphosphoranylides: New methods and applications. 1-22. 2017
- Synthetic Approaches to the Naturally Occurring Anticancer Amaryllidaceae Alkaloids trans -dihydrolycoricidine and trans -dihydronarciclasine. Studies in Natural Products Chemistry. 85-108. 2017
- State‐of‐the‐Art. 413-546. 2005
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conferences
- T91. DEVELOPMENT OF NOVEL BIS-AMIDINES FOR THE TREATMENT OF TOXOPLASMOSIS. Schizophrenia Bulletin. S150-S151. 2018
- Selective induction of apoptosis in cancer cells by pancratistatin that targets mitochondria. International Journal of Molecular Medicine. S23-S23. 2011
- Pancratistatin Selectively Induces Apoptosis in Cancer Cells and Reduces Growth of Colon Xenografts. Pharmaceutical Biology. 8-8. 2010
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journal articles
- Asymmetric Synthesis of the Indolo[2,3‐α]quinolizine Alkaloid (+)‐Cuscutamine via a Diastereoselective Intramolecular Pictet‐Spengler Reaction**. European Journal of Organic Chemistry. 27. 2024
- Mass spectrometry-based metabolomics for the elucidation of alkaloid biosynthesis and function in invasive Vincetoxicum rossicum populations. Phytochemistry. 221:114051-114051. 2024
- Identification of haemanthamine as a phytotoxic alkaloid in Narcissus pseudonarcissus L. (Daffodil) emerging buds. Natural Product Research. 37:4232-4238. 2023
- Rapid entry to phenanthroindolizidine alkaloids via an acid-catalysed acyliminium ion-electrocyclization cascade. Organic and Biomolecular Chemistry. 21:8075-8078. 2023
- Rapid entry to phenanthroindolizidine alkaloids via an acid-catalysed acyliminium ion-electrocyclization cascade. Organic and Biomolecular Chemistry. 21. 2023
- On the use of Organically-Modified Aluminosilicate Clays in the Regioselective Knoevenagel-type Terpenylation of Cyclic 1,3-dicarbonyls En Route to Cannabinoids. Current Organic Chemistry. 27:645-647. 2023
- Truncated ring-A amaryllidaceae alkaloid modulates the host cell integrated stress response, exhibiting antiviral activity to HSV-1 and SARSCoV-2. Scientific Reports. 13:1639. 2023
- A flavin-dependent monooxygenase produces nitrogenous tomato aroma volatiles using cysteine as a nitrogen source. Proceedings of the National Academy of Sciences of the United States of America. 119:e2118676119. 2022
- Metabolite profiling reveals a role for intercellular dihydrocamalexic acid in the response of mature Arabidopsis thaliana to Pseudomonas syringae. Phytochemistry. 187:112747-112747. 2021
- A Catalytic, Oxidative Synthesis of Olivetol, Methyl Olivetolate and Orthogonally Protected Methyl Ether Derivatives. SynOpen. 05:86-90. 2021
- The synthesis of atalantrenes B, C and D, styrene-dimers from the seeds of Atalantia monophylla. Tetrahedron Letters. 63:152716-152716. 2021
- Synthesis of non-nucleoside anti-viral cyclopropylcarboxacyl hydrazones and initial anti-HSV-1 structure-activity relationship studies. Bioorganic and Medicinal Chemistry Letters. 30:127559-127559. 2020
-
The synthesis of densely functionalised α-acyloxy enaminals and enaminonesviaa novel homogeneous silver(
i ) catalysed rearrangement. Chemical Communications. 55:10868-10871. 2019 - Polyphenolic natural products and natural product–inspired steroidal mimics as aromatase inhibitors. Medicinal Research Reviews. 39:1274-1293. 2019
- Synthesis of α-methylstilbenes using an aqueous Wittig methodology and application toward the development of potent human aromatase inhibitors. Bioorganic and Medicinal Chemistry Letters. 29:1395-1398. 2019
- Chemoenzymatic Synthesis of the Antifungal Compound (–)‐Pestynol by a Convergent, Sonogashira Construction of the Central Yne‐Diene. European Journal of Organic Chemistry. 2019:77-79. 2019
- Generation of three-dimensional human neuronal cultures: application to modeling CNS viral infections. Stem Cell Research and Therapy. 9:134. 2018
- R430: A potent inhibitor of DNA and RNA viruses. Scientific Reports. 8:16662. 2018
- Three new polyketides from fruiting bodies of the endophytic ascomyceteXylaria polymorpha. Natural Product Research. 32:2408-2417. 2018
- Asymmetric Entry into 10b-aza-Analogues of Amaryllidaceae Alkaloids Reveals a Pronounced Electronic Effect on Antiviral Activity. ACS Omega. 3:11469-11476. 2018
- Correction: Corrigendum: Cancer Cell Mitochondria Targeting by Pancratistatin Analogs is Dependent on Functional Complex II and III. Scientific Reports. 8:46998. 2018
- Isolation, Synthesis, and Semisynthesis of Amaryllidaceae Constituents from Narcissus and Galanthus sp.: De Novo Total Synthesis of 2-epi-Narciclasine. Journal of natural products. 81:1451-1459. 2018
- One-pot, multicomponent synthesis of 2,3-disubstituted quinazolin-ones with potent and selective activity against Toxoplasma gondii. Bioorganic and Medicinal Chemistry Letters. 28:1642-1646. 2018
- Regioselective Ylide Formation on Acetal-Functionalized Trialkyl Phosphonium Salts: Extending the Scope of Carbonyl Homologation. Synlett. 28:2961-2965. 2017
- Discovery of potent antiviral (HSV-1) quinazolinones and initial structure-activity relationship studies. Bioorganic and Medicinal Chemistry Letters. 27:4601-4605. 2017
- Comparison of three cell-based drug screening platforms for HSV-1 infection. Antiviral Research. 142:136-140. 2017
- Cancer Cell Mitochondria Targeting by Pancratistatin Analogs is Dependent on Functional Complex II and III. Scientific Reports. 7:42957. 2017
- Review of Cytotoxic CA4 Analogues that Do Not Target Microtubules: Implications for CA4 Development. Mini-Reviews in Medicinal Chemistry. 17:1-1. 2017
- Review of Cytotoxic CA4 Analogues that Do Not Target Microtubules: Implications for CA4 Development.. Mini-Reviews in Medicinal Chemistry. 17:1507-1514. 2017
- Total Enantioselective Synthesis of the Endophytic Fungal Polyketide Phomolide H and Its Structural Revision. European Journal of Organic Chemistry. 2017:29-33. 2017
- Structurally simplified biphenyl combretastatin A4 derivatives retain in vitro anti-cancer activity dependent on mitotic arrest. PLoS ONE. 12:e0171806-e0171806. 2017
- DualPhos: a versatile, chemoselective reagent for two-carbon aldehyde to latent ( E )-alkenal homologation and application in the total synthesis of phomolide G. Royal Society Open Science. 3:160374-160374. 2016
- Total Synthesis of the Natural Product (+)‐trans‐Dihydronarciclasine via an Asymmetric Organocatalytic [3+3]‐Cycloaddition and discovery of its potent anti‐Zika Virus (ZIKV) Activity. ChemistrySelect. 1:5895-5899. 2016
- ChemInform Abstract: Asymmetric Organocatalytic Stepwise [2 + 2] Entry to Tetra‐Substituted Heterodimeric and Homochiral Cyclobutanes.. ChemInform. 47:no-no. 2016
- ChemInform Abstract: Enol Ethers as Carbonyl Surrogates in a Modification of the Povarov Synthesis of 3‐Aryl Quinolines and Their anti‐Toxoplasma Activity.. ChemInform. 47:no-no. 2016
- Enol ethers as carbonyl surrogates in a modification of the Povarov synthesis of 3-aryl quinolines and their anti-Toxoplasma activity. Organic and Biomolecular Chemistry. 14:5951-5955. 2016
- Asymmetric Organocatalytic Stepwise [2+2] Entry to Tetra‐Substituted Heterodimeric and Homochiral Cyclobutanes. Chemistry - A European Journal. 22:9111-9115. 2016
- ChemInform Abstract: Enantioselective Total Synthesis of the Proposed Structure of the Endophytic Fungal Metabolite Phomolide G: Structural Revision and Unambiguous Stereochemical Assignment.. ChemInform. 47:no-no. 2016
- Enantioselective Total Synthesis of the Proposed Structure of the Endophytic Fungal Metabolite Phomolide G: Structural Revision and Unambiguous Stereochemical Assignment. European Journal of Organic Chemistry. 2016:688-692. 2016
- iPSC Neuronal Assay Identifies Amaryllidaceae Pharmacophore with Multiple Effects against Herpesvirus Infections. ACS Medicinal Chemistry Letters. 7:46-50. 2016
- Synthesis of the cyanobacterial metabolite nostodione A, structural studies and potent antiparasitic activity against Toxoplasma gondii. Organic and Biomolecular Chemistry. 13:10015-10024. 2015
- ChemInform Abstract: Wittig Reactions of Trialkylphosphine‐Derived Ylides: New Directions and Applications in Organic Synthesis. ChemInform. 46:no-no. 2015
- Tris(3-hydroxypropyl)phosphine (THPP): A mild, air-stable reagent for the rapid, reductive cleavage of small-molecule disulfides. Bioorganic and Medicinal Chemistry Letters. 25:4114-4117. 2015
- Wittig Reactions of Trialkylphosphine-derived Ylides: New Directions and Applications in Organic Synthesis. Phosphorus, Sulfur and Silicon and the Related Elements. 190:619-632. 2015
- Antimitotic activity of structurally simplified biaryl analogs of the anticancer agents colchicine and combretastatin A4. Bioorganic and Medicinal Chemistry Letters. 25:117-121. 2015
- ChemInform Abstract: A Robust, Well‐Defined Homogeneous Silver(I) Catalyst for Mild Intramolecular Hydroamination of 2‐Ethynylanilines Leading to Indoles.. ChemInform. 46:no-no. 2015
- ChemInform Abstract: Enantioselective Organocatalytic Michael/Aldol Sequence: Anticancer Natural Product (+)‐trans‐Dihydrolycoricidine.. ChemInform. 46:no-no. 2015
- Discovery of a new class of cinnamyl-triazole as potent and selective inhibitors of aromatase (cytochrome P450 19A1). Bioorganic and Medicinal Chemistry Letters. 24:4586-4589. 2014
- Total synthesis of the cyanobacterial metabolite nostodione A: discovery of its antiparasitic activity against Toxoplasma gondii. Chemical Communications. 50:8904-8907. 2014
- Enantioselective Organocatalytic Michael/Aldol Sequence: Anticancer Natural Product (+)‐trans‐Dihydrolycoricidine. Angewandte Chemie International Edition. 53:8450-8454. 2014
- Enantioselective Organocatalytic Michael/Aldol Sequence: Anticancer Natural Product (+)‐trans‐Dihydrolycoricidine. Angewandte Chemie International Edition. 126:8590-8594. 2014
- ChemInform Abstract: Synthesis and Anti‐Toxoplasmosis Activity of 4‐Arylquinoline‐2‐carboxylate Derivatives.. ChemInform. 45:no-no. 2014
- High Yielding Synthesis of Carboranes Under Mild Reaction Conditions Using a Homogeneous Silver(I) Catalyst: Direct Evidence of a Bimetallic Intermediate. Angewandte Chemie International Edition. 126:5256-5260. 2014
- High Yielding Synthesis of Carboranes Under Mild Reaction Conditions Using a Homogeneous Silver(I) Catalyst: Direct Evidence of a Bimetallic Intermediate. Angewandte Chemie International Edition. 53:5156-5160. 2014
- ChemInform Abstract: Development of a Robust Reagent for the Two‐Carbon Homologation of Aldehydes to (E)‐α,β‐Unsaturated Aldehydes in Water.. ChemInform. 45:no-no. 2014
- A Robust, Well‐Defined Homogeneous Silver(I) Catalyst for Mild Intramolecular Hydroamination of 2‐Ethynylanilines Leading to Indoles. European Journal of Organic Chemistry. 2014:1622-1629. 2014
- Synthesis and anti-toxoplasmosis activity of 4-arylquinoline-2-carboxylate derivatives. Organic and Biomolecular Chemistry. 12:255-260. 2014
- A scalable process for the synthesis of (E)-pterostilbene involving aqueous Wittig olefination chemistry. Tetrahedron Letters. 54:6303-6306. 2013
- Investigation of aryl halides as ketone bioisosteres: Refinement of potent and selective inhibitors of human cytochrome P450 19A1 (aromatase). Bioorganic and Medicinal Chemistry Letters. 23:6060-6063. 2013
- ChemInform Abstract: Phthalide: A Direct Building‐Block Towards P,O and P,N Hemilabile Ligands. Application in the Palladium‐Catalyzed Suzuki—Miyaura Cross‐Coupling of Aryl Chlorides.. ChemInform. 44:no-no. 2013
- ChemInform Abstract: Discovery of a Robust and Efficient Homogeneous Silver(I) Catalyst for the Cycloaddition of Azides onto Terminal Alkynes.. ChemInform. 44:no-no. 2013
- Development of a robust reagent for the two-carbon homologation of aldehydes to (E)-α,β-unsaturated aldehydes in water. Green Chemistry. 15:3146-3146. 2013
- Phthalide: a direct building-block towards P,O and P,N hemilabile ligands. Application in the palladium-catalysed Suzuki–Miyaura cross-coupling of aryl chlorides. Organic and Biomolecular Chemistry. 11:2404-2404. 2013
- Tandem oxidative radical fragmentation–rearrangement of 2-amino-1,3-benzylidene acetals: a short entry to densely functionalised fully differentiated oxazolidinones. RSC Advances. 3:6771-6771. 2013
- ChemInform Abstract: The Phosphate—Carboxylate Mixed‐Anhydride Method: A Mild, Efficient Process for Ester and Amide Bond Construction.. ChemInform. 43:no-no. 2012
- ChemInform Abstract: One‐Step Synthesis of Reusable, Polymer‐Supported Trialkyl Phosphine Ligands. Application in Suzuki—Miyaura and Alkoxycarbonylation Reactions.. ChemInform. 43:no-no. 2012
- Mild Chemical and Biological Synthesis of Donor–Acceptor Flanked Reporter Stilbenes: Demonstration of a Physiological Wittig Olefination Reaction. European Journal of Organic Chemistry. 2012:6127-6131. 2012
- Symbolic uses of evaluation in the international aid sector: arguments for critical reflection. Evidence & Policy. 8:495-509. 2012
- Discovery of a Robust and Efficient Homogeneous Silver(I) Catalyst for the Cycloaddition of Azides onto Terminal Alkynes. European Journal of Organic Chemistry. 2012:5462-5470. 2012
- ChemInform Abstract: Highly Chemoselective Mono‐Suzuki Arylation Reactions on All Three Dichlorobenzene Isomers and Applications Development.. ChemInform. 43:no-no. 2012
- One-step synthesis of reusable, polymer-supported tri-alkyl phosphine ligands. Application in Suzuki–Miyaura and alkoxycarbonylation reactions. Tetrahedron Letters. 53:3990-3993. 2012
- The phosphate–carboxylate mixed-anhydride method: a mild, efficient process for ester and amide bond construction. Tetrahedron. 68:5415-5421. 2012
- A novel synthetic C-1 analogue of 7-deoxypancratistatin induces apoptosis in p53 positive and negative human colorectal cancer cells by targeting the mitochondria: enhancement of activity by tamoxifen. Investigational New Drugs. 30:1012-1027. 2012
- ChemInform Abstract: The First Well‐Defined Silver(I)‐Complex‐Catalyzed Cycloaddition of Azides onto Terminal Alkynes at Room Temperature.. ChemInform. 43:no-no. 2012
- ChemInform Abstract: A Tandem “On‐Palladium” Heck—Jeffery Amination Route Toward the Synthesis of Functionalized Indole‐2‐carboxylates.. ChemInform. 43:no-no. 2012
- Synthesizing Novel Anthraquinone Natural Product-like Compounds To Investigate Protein–Ligand Interactions in Both an in Vitro and in Vivo Assay: An Integrated Research-Based Third-Year Chemical Biology Laboratory Course. Journal of Chemical Education. 89:743-749. 2012
- Highly Chemoselective Mono‐Suzuki Arylation Reactions on All Three Dichlorobenzene Isomers and Applications Development. European Journal of Organic Chemistry. 2012:2127-2131. 2012
- Discovery of a novel class of aldol-derived 1,2,3-triazoles: Potent and selective inhibitors of human cytochrome P450 19A1 (aromatase). Bioorganic and Medicinal Chemistry Letters. 22:718-722. 2012
- The First Well‐Defined Silver(I)‐Complex‐Catalyzed Cycloaddition of Azides onto Terminal Alkynes at Room Temperature. Chemistry - A European Journal. 17:14727-14730. 2011
-
Palmitoyl‐
dl ‐Carnitine is a Multitarget Inhibitor of Pseudomonas aeruginosa Biofilm Development. ChemBioChem. 12:2759-2766. 2011 - ChemInform Abstract: Amine‐ and Sulfonamide‐Promoted Wittig Olefination Reactions in Water.. ChemInform. 42:no-no. 2011
- A Tandem “On‐Palladium” Heck–Jeffery Amination Route Toward the Synthesis of Functionalized Indole‐2‐carboxylates. European Journal of Organic Chemistry. 2011:6902-6908. 2011
- ChemInform Abstract: One‐Step Entry to P,O‐ and P,N‐Type Heterocyclic Tertiary Phosphine Ligands and Application in Suzuki—Miyaura Cross‐Coupling Reactions.. ChemInform. 42:no-no. 2011
- A convergent synthesis of the immunosuppressant FTY720 employing aqueous Wittig chemistry. Tetrahedron Letters. 52:5672-5675. 2011
- An iterative approach toward the synthesis of discrete oligomeric p-phenylene vinylene organic dyes employing aqueous Wittig chemistry. Tetrahedron Letters. 52:5467-5470. 2011
- Amine‐ and Sulfonamide‐Promoted Wittig Olefination Reactions in Water. Chemistry - A European Journal. 17:8794-8798. 2011
- ChemInform Abstract: Discovery of an Acid‐Promoted [3 + 2] Cyclodimerization of 3‐Vinylindoles and the Development of a General Lewis Acid Catalyzed Process.. ChemInform. 42:no-no. 2011
- Pancratistatin induces apoptosis and autophagy in metastatic prostate cancer cells. International Journal of Oncology. 38:1549-1556. 2011
- ChemInform Abstract: P‐Phenyl‐2,2,6,6‐tetramethylphosphorinan‐4‐ol: An Air‐Stable P,O‐Type Ligand for Palladium‐Mediated Cross‐Coupling Reactions.. ChemInform. 42:no-no. 2011
- ChemInform Abstract: A Direct Synthesis of Functionalized Styrenes and Terminal 1,3‐Dienes via Aqueous Wittig Chemistry with Formalin.. ChemInform. 42:no-no. 2011
- Discovery of an Acid-Promoted [3+2] Cyclodimerization of 3-Vinylindoles and the Development of a General Lewis Acid Catalyzed Process. Synlett. 2011:717-721. 2011
- Sensitization of human melanoma cells by tamoxifen to apoptosis induction by pancratistatin, a nongenotoxic natural compound. Melanoma Research. 21:1-11. 2011
- Human Cytochrome P450 Liability Studies of trans-Dihydronarciclasine: A Readily Available, Potent, and Selective Cancer Cell Growth Inhibitor. Journal of natural products. 74:106-108. 2011
- A direct synthesis of functionalized styrenes and terminal 1,3-dienes via aqueous Wittig chemistry with formalin. Tetrahedron Letters. 52:199-201. 2011
- One step entry to P,O- and P,N-type heterocyclic tertiary phosphine ligands and application in Suzuki–Miyaura cross-coupling reactions. Organic and Biomolecular Chemistry. 9:4421-4421. 2011
- Pancratistatin Selectively Targets Cancer Cell Mitochondria and Reduces Growth of Human Colon Tumor Xenografts. Molecular Cancer Therapeutics. 10:57-68. 2011
- P‐Phenyl‐2,2,6,6‐tetramethylphosphorinan‐4‐ol: An Air‐Stable P,O‐Type Ligand for Palladium‐Mediated Cross‐Coupling Reactions. European Journal of Organic Chemistry. 2010:6824-6830. 2010
- Pancratistatin induces apoptosis in clinical leukemia samples with minimal effect on non-cancerous peripheral blood mononuclear cells. Cancer Cell International. 10:6. 2010
- ChemInform Abstract: Dichotomous Reactivity in the Reaction of Triethyl‐ and Triphenylphosphane HBr Salts with Dimethyl Acetals: A Novel Entry to α‐Alkoxy‐Functionalized Ylides and General Synthesis of Vinyl Ethers and Alkoxy Dienes.. ChemInform. 41:no-no. 2010
- A Sol−Gel-Derived Acetylcholinesterase Microarray for Nanovolume Small-Molecule Screening. Analytical Chemistry. 82:9365-9373. 2010
- ChemInform Abstract: Microwave‐Assisted, Aqueous Wittig Reactions: Organic‐Solvent‐ and Protecting‐Group‐Free Chemoselective Synthesis of Functionalized Alkenes.. ChemInform. 41:no-no. 2010
- ChemInform Abstract: A Short Synthesis of the Antileukemic Sesquiterpene (+)‐Caparratriene Employing Aqueous Wittig Chemistry.. ChemInform. 41:no-no. 2010
- Structure–activity studies on acetylcholinesterase inhibition in the lycorine series of Amaryllidaceae alkaloids. Bioorganic and Medicinal Chemistry Letters. 20:5290-5294. 2010
- Cytochrome P450 3A4 Inhibitory Activity Studies within the Lycorine series of Alkaloids. Natural Product Communications. 5:1934578X1000500-1934578X1000500. 2010
- Dichotomous Reactivity in the Reaction of Triethyl‐ and Triphenylphosphane HBr Salts with Dimethyl Acetals: A Novel Entry to α‐Alkoxy‐Functionalized Ylides and General Synthesis of Vinyl Ethers and Alkoxy Dienes. European Journal of Organic Chemistry. 2010:3587-3591. 2010
- Microwave‐Assisted, Aqueous Wittig Reactions: Organic‐Solvent‐ and Protecting‐Group‐Free Chemoselective Synthesis of Functionalized Alkenes. Chemistry - A European Journal. 16:6756-6760. 2010
- A short synthesis of the anti-leukemic sesquiterpene (+)-caparratriene employing aqueous Wittig chemistry. Tetrahedron Letters. 51:3197-3199. 2010
- Potent and selective inhibition of human cytochrome P450 3A4 by seco-pancratistatin structural analogs. Bioorganic and Medicinal Chemistry Letters. 20:2335-2339. 2010
- ChemInform Abstract: A Novel P,O‐Type Phosphorinane Ligand for the Suzuki—Miyaura Cross‐Coupling of Aryl Chlorides.. ChemInform. 41:no-no. 2010
- ChemInform Abstract: Aqueous Wittig Reactions of Semi‐Stabilized Ylides. A Straightforward Synthesis of 1,3‐Dienes and 1,3,5‐Trienes.. ChemInform. 41:no-no. 2010
- ChemInform Abstract: Development of a One‐Pot Method for the Homologation of Aldehydes to Carboxylic Acids.. ChemInform. 41:no-no. 2010
- ChemInform Abstract: Highly Stereoselective and General Synthesis of (E)‐Stilbenes and Alkenes by Means of an Aqueous Wittig Reaction.. ChemInform. 40:no-no. 2009
- Isolation of flavonoids from the heartwood and resin of Prunus avium and some preliminary biological investigations. Phytochemistry. 70:2040-2046. 2009
- ChemInform Abstract: A Synthesis of Sulfonamide Analogues of Platensimycin Employing a Palladium‐Mediated Carbonylation Strategy.. ChemInform. 40:no-no. 2009
- A novel P,O-type phosphorinane ligand for the Suzuki–Miyaura cross-coupling of aryl chlorides. Tetrahedron Letters. 50:5599-5601. 2009
- Aqueous Wittig reactions of semi-stabilized ylides. A straightforward synthesis of 1,3-dienes and 1,3,5-trienes. Tetrahedron Letters. 50:5737-5740. 2009
- Structure–activity studies on seco-pancratistatin analogs: Potent inhibitors of human cytochrome P450 3A4. Bioorganic and Medicinal Chemistry Letters. 19:5607-5612. 2009
- Development of a one-pot method for the homologation of aldehydes to carboxylic acids. Tetrahedron. 65:7794-7800. 2009
- ChemInform Abstract: Efficient Palladium‐Catalyzed Carbonylative and Suzuki—Miyaura Cross‐Coupling Reactions with Bis(di‐tert‐butylphosphino)‐o‐xylene.. ChemInform. 40:no-no. 2009
- Highly Stereoselective and General Synthesis of (E)‐Stilbenes and Alkenes by Means of an Aqueous Wittig Reaction. European Journal of Organic Chemistry. 2009:4031-4035. 2009
- A synthesis of sulfonamide analogs of platensimycin employing a palladium-mediated carbonylation strategy. Tetrahedron Letters. 50:4087-4091. 2009
- Selective cytochrome P450 3A4 inhibitory activity of Amaryllidaceae alkaloids. Bioorganic and Medicinal Chemistry Letters. 19:3233-3237. 2009
- Efficient palladium-catalysed carbonylative and Suzuki–Miyaura cross-coupling reactions with bis(di-tert-butylphosphino)-o-xylene. Tetrahedron Letters. 50:2342-2346. 2009
- Structure-activity studies on the lycorine pharmacophore: A potent inducer of apoptosis in human leukemia cells. Phytochemistry. 70:913-919. 2009
- Structure Activity Studies on the Crinane Alkaloid Apoptosis-inducing Pharmacophore. Natural Product Communications. 4:1934578X0900400-1934578X0900400. 2009
- ChemInform Abstract: Stereoselective Wittig Olefination Reactions Employing a Novel ortho‐P‐Aryl Alkoxide Effect.. ChemInform. 40:no-no. 2009
- ChemInform Abstract: Direct Formation of Esters and Amides from Carboxylic Acids Using Diethyl Chlorophosphate in Pyridine.. ChemInform. 40:no-no. 2009
- ChemInform Abstract: A Direct Synthesis of Vinylphosphonium Salts from α‐Trimethylsilyl Ylides and Non‐Enolizable Aldehydes.. ChemInform. 40:no-no. 2009
- Stereoselective Wittig olefination reactions employing a novel ortho-P-aryl alkoxide effect. Tetrahedron Letters. 49:7054-7057. 2008
- Direct formation of esters and amides from carboxylic acids using diethyl chlorophosphate in pyridine. Tetrahedron Letters. 49:6344-6347. 2008
- A Direct Synthesis of Vinylphosphonium Salts from α‐Trimethylsilyl Ylides and Non‐Enolizable Aldehydes. Chemistry - A European Journal. 14:8469-8472. 2008
- ChemInform Abstract: Rapid and Efficient Entry to Vinyl Silanes from Aldehydes Employing a Novel Metalation—Peterson Sequence.. ChemInform. 39:no-no. 2008
- ChemInform Abstract: An Improved Synthesis of α‐Phosphonoenamines Based on a Modified Peterson Olefination.. ChemInform. 39:no-no. 2008
- ChemInform Abstract: Efficient Carbonylation Reactions in Phosphonium Salt Ionic Liquids: Anionic Effects.. ChemInform. 39:no-no. 2008
- Synergy of pancratistatin and tamoxifen on breast cancer cells in inducing apoptosis by targeting mitochondria. Cancer Biology and Therapy. 7:376-384. 2008
- Synthesis and Biological Evaluation of Fully Functionalized seco-Pancratistatin Analogues. Journal of natural products. 71:357-363. 2008
- An improved synthesis of α-phosphonoenamines based on a modified Peterson olefination. Tetrahedron Letters. 49:281-285. 2008
- Rapid and efficient entry to vinyl silanes from aldehydes employing a novel metalation–Peterson sequence. Chemical Communications. 0:1244-1244. 2008
- Discovery of the Apoptosis-Inducing Activity and High Accumulation of the Butenolides, Menisdaurilide and Aquilegiolide, in Dicentra spectabilis. Planta Medica. 73:1543-1547. 2007
- Selective cytotoxicity of Pancratistatin-related natural Amaryllidaceae alkaloids: evaluation of the activity of two new compounds. Cancer Cell International. 7:10. 2007
-
Unusual Magnesium Chloride Catalyzed Non‐Evans anti‐Aldol Reactions of an Enolizable
L ‐Threose Derivative. European Journal of Organic Chemistry. 2007:5669-5673. 2007 - Efficient carbonylation reactions in phosphonium salt ionic liquids: Anionic effects. Organic Letters. 9:4575-4578. 2007
- Efficient Carbonylation Reactions in Phosphonium Salt Ionic Liquids: Anionic Effects. Organic Letters. 9:4575-4578. 2007
- A Pronounced Anionic Effect in the Pd‐Catalyzed Buchwald—Hartwig Amination Reaction Revealed in Phosphonium Salt Ionic Liquids.. ChemInform. 38:no-no. 2007
- Scope and Mechanistic Insights into the Use of Tetradecyl(trihexyl)phosphonium Bistriflimide: A Remarkably Selective Ionic Liquid Solvent for Substitution Reactions.. ChemInform. 38:no-no. 2007
- Selective apoptosis-inducing activity of crinum-type Amaryllidaceae alkaloids. Phytochemistry. 68:1068-1074. 2007
- A Pronounced Anionic Effect in the Pd‐Catalyzed Buchwald–Hartwig Amination Reaction Revealed in Phosphonium Salt Ionic Liquids. European Journal of Organic Chemistry. 2007:1423-1428. 2007
- Scope and Mechanistic Insights into the Use of Tetradecyl(trihexyl)phosphonium Bistriflimide: A Remarkably Selective Ionic Liquid Solvent for Substitution Reactions. Chemistry - A European Journal. 12:9314-9322. 2006
- Phosphorinanes as Ligands for Palladium‐Catalyzed Cross‐Coupling Chemistry.. ChemInform. 37:no-no. 2006
- A Synthesis of 3‐Deoxydihydrolycoricidine: Refinement of a Structurally Minimum Pancratistatin Pharmacophore.. ChemInform. 37:no-no. 2006
- Phosphonium Salts as Room‐Temperature Ionic Liquids in Organic Synthesis. ChemInform. 37:no-no. 2006
- Phosphorinanes as ligands for palladium-catalyzed cross-coupling chemistry. Organic Letters. 8:103-105. 2006
- Phosphorinanes as Ligands for Palladium-Catalyzed Cross-Coupling Chemistry. Organic Letters. 8:103-105. 2006
- Application of Phosphonium Salts as Catalysts. ChemInform. 36:no-no. 2005
- A synthesis of 3-deoxydihydrolycoricidine: Refinement of a structurally minimum pancratistatin pharmacophore. Bioorganic and Medicinal Chemistry Letters. 15:5315-5318. 2005
- Dimethylmalonyltrialkylphosphoranes: Probing the Steric Effect on Phosphorus and Its Stereochemical Consequence in Esterification Reactions of Chiral Secondary Alcohols.. ChemInform. 36:no-no. 2005
- A Mild Esterification Process in Phosphonium Salt Ionic Liquid.. ChemInform. 36:no-no. 2005
- Pancratistatin causes early activation of caspase-3 and the flipping of phosphatidyl serine followed by rapid apoptosis specifically in human lymphoma cells. Cancer Chemotherapy and Pharmacology. 56:29-38. 2005
- A mild esterification process in phosphonium salt ionic liquid. Tetrahedron Letters. 46:3641-3644. 2005
- Dimethylmalonyltrialkylphosphoranes: probing the steric effect on phosphorus and its stereochemical consequence in esterification reactions of chiral secondary alcohols. Journal of Organometallic Chemistry. 690:2548-2552. 2005
- Pancratistatin: A natural anti-cancer compound that targets mitochondria specifically in cancer cells to induce apoptosis. Apoptosis : an international journal on programmed cell death. 10:619-630. 2005
- Phosphaadamantanes as Ligands for Palladium Catalyzed Cross‐Coupling Chemistry: Library Synthesis, Characterization, and Screening in the Suzuki Coupling of Alkyl Halides and Tosylates Containing β‐Hydrogens with Boronic Acids and Alkylboranes.. ChemInform. 36:no-no. 2005
- Phospha‐adamantanes as Ligands for Organopalladium Chemistry: Aminations of Aryl Halides.. ChemInform. 36:no-no. 2005
- Heck Reactions of Aryl Halides in Phosphonium Salt Ionic Liquids: Library Screening and Applications.. ChemInform. 36:no-no. 2005
- Induction of Apoptotic Cell Death Specifically in Rat and Human Cancer Cells by Pancratistatin. Artificial Cells, Nanomedicine and Biotechnology. 33:279-295. 2005
- Palladium Complexes of 1,3,5,7‐Tetramethyl‐2,4,8‐trioxa‐6‐phenyl‐6‐phosphaadamantane: Synthesis, Crystal Structure and Use in the Suzuki and Sonogashira Reactions and the α‐Arylation of Ketones.. ChemInform. 35:no-no. 2004
- Phospha-adamantanes as ligands for organopalladium chemistry: aminations of aryl halides. Tetrahedron Letters. 45:8319-8321. 2004
- Phosphonium salts as room-temperature ionic liquids in organic synthesis. Chimica Oggi. 22:13-16. 2004
- Phosphaadamantanes as ligands for palladium catalyzed cross-coupling chemistry:: Library synthesis, characterization, and screening in the Suzuki coupling of alkyl halides and tosylates containing β-hydrogens with boronic acids and alkylboranes. Journal of Organic Chemistry. 69:7635-7639. 2004
- Heck reactions of aryl halides in phosphonium salt ionic liquids: library screening and applications. Tetrahedron Letters. 45:7629-7631. 2004
- Phosphaadamantanes as Ligands for Palladium Catalyzed Cross-Coupling Chemistry: Library Synthesis, Characterization, and Screening in the Suzuki Coupling of Alkyl Halides and Tosylates Containing β-Hydrogens with Boronic Acids and Alkylboranes. Journal of Organic Chemistry. 69:7635-7639. 2004
- Palladium Complexes of 1,3,5,7-Tetramethyl-2,4,8-trioxa-6-phenyl-6-phosphaadamantane: Synthesis, Crystal Structure and Use in the Suzuki and Sonogashira Reactions and the α-Arylation of Ketones. Journal of Organic Chemistry. 69:5082-5086. 2004
- Solid-phase Suzuki cross-coupling reactions using a phosphine ligand based on a phospha-adamantane framework. Tetrahedron Letters. 45:5661-5663. 2004
- Antineoplastic Agents 491.1 Synthetic Conversion of Aaptamine to Isoaaptamine, 9-Demethylaaptamine, and 4-Methylaaptamine. Journal of Organic Chemistry. 69:2251-2256. 2004
- Phosphonium Salt Catalyzed Henry Nitroaldol Reactions. Letters in Organic Chemistry. 1:137-139. 2004
- Antineoplastic Agents. 380. Isolation and X-ray Crystal Structure Determination of Isoaaptamine from the Republic of Singapore Hymeniacidon sp. and Conversion to the Phosphate Prodrug Hystatin 1. Journal of natural products. 67:506-509. 2004
- A highly efficient general synthesis of phosphine–borane complexes. Tetrahedron Letters. 45:407-409. 2004
- Regiocontrol in the Oxidative Radical Fragmentation of Benzilidene Acetals and Its Mechanistic Implications. Journal of Organic Chemistry. 69:563-565. 2004
- The Role of Acyloxyphosphonium Ions and the Stereochemical Influence of Base in the Phosphorane‐Mediated Esterification of Alcohols. Angewandte Chemie International Edition. 115:4185-4188. 2003
- The Role of Acyloxyphosphonium Ions and the Stereochemical Influence of Base in the Phosphorane‐Mediated Esterification of Alcohols. Angewandte Chemie International Edition. 42:4051-4054. 2003
- Novel Class of Tertiary Phosphine Ligands Based on a Phospha‐adamantane Framework and Use in the Suzuki Cross‐Coupling Reactions of Aryl Halides under Mild Conditions.. ChemInform. 34:no-no. 2003
- Dimethylmalonyltrialkylphosphoranes: New General Reagents for Esterification Reactions Allowing Controlled Inversion or Retention of Configuration on Chiral Alcohols.. ChemInform. 34:no-no. 2003
- Novel Class of Tertiary Phosphine Ligands Based on a Phospha-adamantane Framework and Use in the Suzuki Cross-Coupling Reactions of Aryl Halides under Mild Conditions. Organic Letters. 5:953-955. 2003
- Dimethylmalonyltrialkylphosphoranes: New General Reagents for Esterification Reactions Allowing Controlled Inversion or Retention of Configuration on Chiral Alcohols. Journal of Organic Chemistry. 68:1597-1600. 2003
- Lipase-catalyzed stereoselective resolution and desymmetrization of binaphthols. Tetrahedron: Asymmetry: the international journal for rapid publication on all aspects of asymmetry in organic, inorganic, organometallic, physical and bioorganic chemistry. 14:289-291. 2003
- Suzuki Cross‐Coupling Reactions of Aryl Halides in Phosphonium Salt Ionic Liquid under Mild Conditions.. ChemInform. 33:118-118. 2002
- Suzuki cross-coupling reactions of aryl halides in phosphonium salt ionic liquid under mild conditions. Chemical Communications. 0:1986-1987. 2002
- On the direct 2,3-hydroxyl-group differentiation of tartaric acid esters. Tetrahedron Letters. 43:3857-3861. 2002
- ChemInform Abstract: A New Structural Motif for Rigid C2‐Symmetrical Propeller‐Shaped 1,2‐Diamines Employing Double Aromatic π‐Stacking.. ChemInform. 33:no-no. 2002
- ChemInform Abstract: Selective Addition of Grignard Reagents to 2,3‐O‐Isopropylidene Bis‐Weinreb Tartaric Acid Amide.. ChemInform. 33:no-no. 2002
- A new structural motif for rigid C2-symmetrical propeller-shaped 1,2-diamines employing double aromatic π-stackingElectronic supplementary data (ESI) available: colour figure showing π-stacking in compound 12. See http://www.rsc.org/suppdata/cc/b1/b106641b/. Chemical Communications. 1:2384-2385. 2001
- Selective addition of Grignard reagents to 2,3-O-isopropylidene bis-Weinreb tartaric acid amide. Tetrahedron Letters. 42:5609-5612. 2001
- ChemInform Abstract: Studies Directed Towards the Refinement of the Pancratistatin Cytotoxic Pharmacophore.. ChemInform. 32:no-no. 2001
- Novel chiral phosphines derived from limonene: the synthesis and structure of 4,8-dimethyl-2-phosphabicyclo[3.3.1]nonane. Tetrahedron Letters. 42:2609-2612. 2001
- Studies directed towards the refinement of the pancratistatin cytotoxic pharmacophore. Bioorganic and Medicinal Chemistry Letters. 11:169-172. 2001
- ChemInform Abstract: Synthetic Approaches to the Eudistomin Marine Alkaloids. ChemInform. 31:no-no. 2000
- Synthetic Approaches to the Eudistomin Marine Alkaloids. Current Organic Chemistry. 4:121-138. 2000
- Stereoselective Oxidative Dimerization of (1R)-Camphor. A Short Synthesis of exo,exo‘-3,3‘-Biisoborneol. Journal of Organic Chemistry. 64:5312-5314. 1999
- ChemInform Abstract: The Ultrasound‐Promoted Knoevenagel Condensation of Aromatic Aldehydes.. ChemInform. 30:no-no. 1999
- The ultrasound promoted Knoevenagel condensation of aromatic aldehydes. Tetrahedron Letters. 39:8013-8016. 1998
- ChemInform Abstract: Diastereoselective Intramolecular Nitroaldol Entry to Lycoricidine Alkaloids.. ChemInform. 29:no-no. 1998
- Diastereoselective intramolecular nitroaldol entry to lycoricidine alkaloids. Chemical Communications. 0:933-934. 1998
- ChemInform Abstract: Synthesis of Enantiomerically Pure β‐Amino Acids Starting from L‐ and D‐aspartic Acids. ChemInform. 28:no-no. 1997
- Antineoplastic Agents. 362. Isolation and X-ray Crystal Structure of Dibromophakellstatin from the Indian Ocean Sponge Phakellia mauritiana. Journal of natural products. 60:180-183. 1997
- ChemInform Abstract: The Enantioselective Synthesis of β‐Amino Acids, Their α‐ Hydroxy Derivatives, and the N‐Terminal Components of Bestatin and Microginin.. ChemInform. 27:no-no. 1996
- The Enantioselective Synthesis of β‐Amino Acids, their α‐hydroxy derivatives, and the N‐terminal components of bestatin and microginin. Helvetica Chimica Acta. 79:1203-1216. 1996
- ChemInform Abstract: Selective Methylation and Stereoselective Reduction of a β‐ Carboline to a N(2)‐Methyl‐1,2,3,4‐tetrahydro‐β‐carboline.. ChemInform. 27:no-no. 1996
- Selective methylation and stereoselective reduction of a β-carboline to a N(2)-methyl-1,2,3,4-tetrahydro-β-carboline.. Tetrahedron Letters. 36:7965-7966. 1995
- ChemInform Abstract: A Concise Enantioselective Synthesis of N‐Morpholinosphingosines from D‐Aspartic Acid.. ChemInform. 26:no-no. 1995
- Associative Behavior and Diffusion Coefficients of Hydrophobically Modified Poly(N,N-dimethylacrylamides). Macromolecules. 28:4150-4158. 1995
- ChemInform Abstract: A Practical Synthesis of (2S,3R)‐3‐Amino‐2‐methylpentanoic Acid (VIII) from L‐Aspartic Acid.. ChemInform. 26:no-no. 1995
- A concise enantioselective synthesis of N-morpholinosphingosines from D-aspartic acid. Chemical Communications. 0:123-123. 1995
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A Practical Synthesis of (2S, 3R)‐3‐Amino‐2‐methylpentanoic Acid from
L ‐Aspartic Acid. Helvetica Chimica Acta. 77:2142-2146. 1994 - ChemInform Abstract: Formamidine as a Versatile Protecting Group for Primary Amines: A Mild Prodedure for Hydrolytic Removal.. ChemInform. 25:no-no. 1994
- ChemInform Abstract: Diastereoselective Pictet‐Spengler Reactions of L‐(Boc)Phenylalaninal and L‐(Boc)Prolinal: Biomimetic Syntheses of Eudistomin T and (‐)‐ Woodinine.. ChemInform. 25:no-no. 1994
- Formamidine as a Versatile Protecting Group for Primary Amines: A Mild Procedure for Hydrolytic Removal. Synthetic Communications. 24:1617-1624. 1994
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Diastereoselective Pictet–Spengler reactions of
L -(Boc)phenylalaninal andL -(Boc)prolinal: biomimetic syntheses of eudistomin T and (–)-woodinine. Organic and Biomolecular Chemistry. 0:1329-1337. 1994 - ChemInform Abstract: A Simple, High‐Yielding Synthesis of N‐tert‐Butoxycarbonyl α‐ Amino Esters: Precursors for α‐Amino Aldehydes.. ChemInform. 23:no-no. 1992
- A Simple, High-Yielding Synthesis of N-t-Butoxycarbonyl α-Amino Esters: Precursors for α-Amino Aldehydes. Synthetic Communications. 22:979-985. 1992
- Diastereoselective pictet-spengler reactions of L-(boc)prolinal: a biomimetic synthesis of eudistomins H and I, and woodinine. Tetrahedron Letters. 32:4875-4878. 1991
- A comment on the paper “uniform polymer particles by dispersion polymerization in alcohol,” by C. M. Tseng, Y. Y. Lu, M. S. El‐Aasser, and J. W. Vanderhoff [J. polym. sci. polym. chem. Ed. 24, 2995 (1986)]. Journal of Polymer Science. 28:2569-2574. 1990
- Dispersion polymerization of styrene in polar solvents. 6. Influence of reaction parameters on particle size and molecular weight in poly(N-vinylpyrrolidone)-stabilized reactions. Macromolecules. 23:3104-3109. 1990
- THE SYNTHESIS OF EUDISTOMIN-S-BETA-CARBOLINE AND EUDISTOMIN-T-BETA-CARBOLINE FROM THE TUNICATE EUDISTOMA-OLIVACEUM. Heterocycles. 29:2057-2059. 1989
- The Synthesis of Eudistomins S and T: b-carbolines from the Tunicate Eudistoma olivaceum. Heterocycles. 29:2057-2057. 1989