Journal article
Aqueous Wittig reactions of semi-stabilized ylides. A straightforward synthesis of 1,3-dienes and 1,3,5-trienes
Abstract
A direct synthesis of 1,3-dienes and 1,3,5-trienes from the reaction of semi-stabilized ylides and a range of saturated and unsaturated aldehydes is reported in water as solvent, employing sodium hydroxide as base. The water-soluble phosphine oxide side product is removed simply by aqueous partitioning of the organic products.
Authors
McNulty J; Das P
Journal
Tetrahedron Letters, Vol. 50, No. 41, pp. 5737–5740
Publisher
Elsevier
Publication Date
October 2009
DOI
10.1016/j.tetlet.2009.07.133
ISSN
0040-4039