Journal article
Palladium Complexes of 1,3,5,7-Tetramethyl-2,4,8-trioxa-6-phenyl-6-phosphaadamantane: Synthesis, Crystal Structure and Use in the Suzuki and Sonogashira Reactions and the α-Arylation of Ketones
Abstract
Palladium complexes of 1,3,5,7-tetramethyl-2,4,8-trioxa-6-phenyl-6-phosphaadamantane were prepared and characterized with Pd[1,3,5,7-tetramethyl-2,4,8-trioxa-6-phenyl-6-phosphaadamantane](2).dba shown to be an effective catalyst for use in the Suzuki and Sonogashira reactions and the alpha-arylation of ketones. Couplings using this versatile complex proceeded in excellent yields under mild conditions.
Authors
Adjabeng G; Brenstrum T; Frampton CS; Robertson AJ; Hillhouse J; McNulty J; Capretta A
Journal
The Journal of Organic Chemistry, Vol. 69, No. 15, pp. 5082–5086
Publisher
American Chemical Society (ACS)
Publication Date
July 1, 2004
DOI
10.1021/jo049474x
ISSN
0022-3263