Journal article
Formamidine as a Versatile Protecting Group for Primary Amines: A Mild Procedure for Hydrolytic Removal
Abstract
A mild, zinc chloride-promoted cleavage of N,N-dimethyl-formamidine derivatives of primary amines to the free amines is described. Under slightly different hydrolytic conditions the corresponding N-formyl derivatives can be isolated.
Authors
Toste D; McNulty J; Still IWJ
Journal
Synthetic Communications, Vol. 24, No. 11, pp. 1617–1624
Publisher
Taylor & Francis
Publication Date
June 1994
DOI
10.1080/00397919408010163
ISSN
0039-7911