abstract
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A total synthesis of the cyanobacterial natural product nostodione A is reported involving a convergent, diversity-oriented route, enabling the assembly of a mini-library of structural analogues.
Synthesis of the cyanobacterial metabolite nostodione A, structural studies and potent antiparasitic activity against Toxoplasma gondii
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authors
publication date
- October 21, 2015
has subject area
- 0304 Medicinal and Biomolecular Chemistry (FoR)
- 0305 Organic Chemistry (FoR)
- Antiprotozoal Agents (MeSH)
- Cyanobacteria (MeSH)
- Drug Design (MeSH)
- Humans (MeSH)
- Indole Alkaloids (MeSH)
- Models, Molecular (MeSH)
- Organic Chemistry (Science Metrix)
- Structure-Activity Relationship (MeSH)
- Toxoplasma (MeSH)
- Toxoplasmosis (MeSH)