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Amine‐ and Sulfonamide‐Promoted Wittig Olefination...
Journal article

Amine‐ and Sulfonamide‐Promoted Wittig Olefination Reactions in Water

Abstract

Amine-promoted olefination: The reaction of a phosphonium salt and an aldehyde in water to yield alkenes with high E-configurational control is promoted by catalytic amounts of non-basic amines in aqueous bicarbonate media. Possible catalytic cycles involving imines and iminium intermediates are discussed.

Authors

McNulty J; McLeod D

Journal

Chemistry - A European Journal, Vol. 17, No. 32, pp. 8794–8798

Publisher

Wiley

Publication Date

August 2011

DOI

10.1002/chem.201101153

ISSN

0947-6539