Journal article
Isolation of flavonoids from the heartwood and resin of Prunus avium and some preliminary biological investigations
Abstract
An investigation of the constituents in heartwood and resin of Prunus avium is reported. A mini-library of structurally diverse flavanones and flavones was screened for human cytochrome P450 1A1, 3A4 and 19 (aromatase) inhibition, and for antifungal activity against a panel of pathogenic fungi. The defensive role of these natural plant flavonoids as antifungal phytoalexins and phytoanticipins is discussed.
Authors
McNulty J; Nair JJ; Bollareddy E; Keskar K; Thorat A; Crankshaw DJ; Holloway AC; Khan G; Wright GD; Ejim L
Journal
Phytochemistry, Vol. 70, No. 17-18, pp. 2040–2046
Publisher
Elsevier
Publication Date
12 2009
DOI
10.1016/j.phytochem.2009.08.018
ISSN
0031-9422