Ligands
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N,N-Bis(2-mercaptoethyl)methylamine: A New Coligand for Tc-99m Labeling of Hydrazinonicotinamide Peptides Academic Article
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A Comparison of Toll-Like Receptor 5 and 21 Ligands as Adjuvants for a Formaldehyde Inactivated H9N2 Avian Influenza Virus Vaccine in Chickens Academic Article
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A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease Academic Article
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A New Strategy for the Preparation of Peptide-Targeted Technetium and Rhenium Radiopharmaceuticals. The Automated Solid-Phase Synthesis, Characterization, Labeling, and Screening of a Peptide-Ligand Library Targeted at the Formyl Peptide Receptor Academic Article
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A PPARγ mutant serves as a dominant negative inhibitor of PPAR signaling and is localized in the nucleus Academic Article
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A Solid-Phase Labeling Strategy for the Preparation of Technetium and Rhenium Bifunctional Chelate Complexes and Associated Peptide Conjugates Academic Article
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A critical role for IL‐15 in TLR‐mediated innate antiviral immunity against genital HSV‐2 infection Academic Article
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A hydrocarbon ruler measures palmitate in the enzymatic acylation of endotoxin Academic Article
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A ligand of the p65/p95 receptor suppresses perforant path kindling, kindling-induced mossy fiber sprouting, and hilar area changes in adult rats Academic Article
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A naturally occurring transcript variant of MARCO reveals the SRCR domain is critical for function Academic Article
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A p56 Ligand Serves as a Coactivator of an Orphan Nuclear Hormone Receptor Academic Article
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A robust strategy for the preparation of libraries of metallopeptides. A new paradigm for the discovery of targeted molecular imaging and therapy agents Academic Article
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ACCUMULATION OF LIGANDS FOR ARYL HYDROCARBON AND SEX STEROID RECEPTORS IN FISH EXPOSED TO TREATED EFFLUENT FROM A BLEACHED SULFITE/GROUNDWOOD PULP AND PAPER MILL Academic Article
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ADAM17 activation and regulation of profibrotic responses by high glucose requires its C-terminus and FAK kinase Academic Article
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Access and Binding of Local Anesthetics in the Closed Sodium Channel Academic Article
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Allosteric Mechanisms of Nonadditive Substituent Contributions to Protein-Ligand Binding Academic Article
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Alloxan inhibits ligand binding to adrenoceptors of vascular smooth muscle microsomes Academic Article
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Analyses of cellular multimerin 1 receptors: in vitro evidence of binding mediated by αΙΙbβ3 and αvβ3 Academic Article
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Analysis of the pi-pi stacking interactions between the aminoglycoside antibiotic kinase APH(3')-IIIa and its nucleotide ligands Academic Article
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Aryl hydrocarbon receptor ligand production by the gut microbiota is decreased in celiac disease leading to intestinal inflammation Academic Article
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Assessing wild fish exposure to ligands for sex steroid receptors from pulp and paper mill effluents in the Biobio River Basin, Central Chile Academic Article
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Bio-Solid-Phase Extraction/Tandem Mass Spectrometry for Identification of Bioactive Compounds in Mixtures Academic Article
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Bridging the Gap between in Vitro and in Vivo Imaging: Isostructural Re and99mTc Complexes for Correlating Fluorescence and Radioimaging Studies Academic Article
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CONSTITUENTS WITHIN PULP MILL EFFLUENT DEPLETE RETINOID STORES IN WHITE SUCKER AND BIND TO RAINBOW TROUT RETINOIC ACID RECEPTORS AND RETINOID X RECEPTORS Academic Article
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Ca2+ channel ligand activities in uterine smooth muscle: influence of hormonal status Academic Article
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Carbamoylphosphate requirement for synthesis of the active center of [NiFe]‐hydrogenases Academic Article
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Cellular binding and/or uptake of nickel(II) ions. Academic Article
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Characterization of a Novel Primary Mammary Tumor Cell Line Reveals that Cyclin D1 Is Regulated by the Type I Insulin-Like Growth Factor Receptor Academic Article
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Chemical Exchange Reaction of Glycinatocopper(II) Complex in Water: A Theoretical Study Academic Article
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Chemical modification reveals involvement of tyrosine in ligand binding to dopamine D1 and D2 receptors. Academic Article
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Clorgyline-induced switch from locomotion to mouthing in sensitization to the dopamine D2/D3 agonist quinpirole in rats: role of sigma and imidazoline I2 receptors Academic Article
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Cognitive impairments of alcoholic cirrhotic patients: correlation with endogenous benzodiazepine receptor ligands and increased affinity of platelet receptors. Academic Article
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Comparison of lowest energy conformations of dimethylcurine and methoxyverapamil: Evidence of ternary association of calcium channel, Ca2+, and calcium entry blockers Academic Article
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Computational Analysis of the Crystal and Cryo-EM Structures of P-Loop Channels with Drugs Academic Article
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Computational Structural Pharmacology and Toxicology of Voltage-Gated Sodium Channels Chapter
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Conformational Analysis of the Ca2+-Bound Opioid Peptides: Implications for Ligand-Receptor Interaction Academic Article
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Conformational and Electrostatic Similarity Between Polyprotonated and Ca2+-Boundμ-Opioid Peptides Academic Article
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Conformational states of aspartate transcarbamoylase stabilized with a cross-linking reagent. Academic Article
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Controlling Gene Expression in Living Cells Through Small Molecule-RNA Interactions Academic Article
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Cross-chimeric analysis of selectivity of secretin and VPAC(1) receptor activation. Academic Article
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Cutting Edge: FimH Adhesin of Type 1 Fimbriae Is a Novel TLR4 Ligand Academic Article
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Design and Synthesis of Photoaffinity-Labeling Ligands of the l-Prolyl-l-leucylglycinamide Binding Site Involved in the Allosteric Modulation of the Dopamine Receptor Academic Article
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Design and synthesis of site directed maleimide bifunctional chelators for technetium and rhenium Academic Article
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Determination of Strong Ligand Sites in Sewage Effluent-Impacted Waters by Competitive Ligand Titration with Silver Academic Article
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Different binding sites for the neuropeptide Y Y1 antagonists 1229U91 and J-104870 on human Y1 receptors Academic Article
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Differential inhibitory effects of melatonin analogs and three naphthalenic ligands on 2-[125I]iodomelatonin binding to chicken tissues Academic Article
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Differential response of primitive human CD34− and CD34+ hematopoietic cells to the Notch ligand Jagged-1 Academic Article
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Docking flexible ligands in proteins with a solvent exposure- and distance-dependent dielectric function Academic Article
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Dopamine D2 receptors quantified in vivo in human narcolepsy Academic Article
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Dynamic unfolding of a regulatory subunit of cAMP‐dependent protein kinase by capillary electrophoresis: Impact of cAMP dissociation on protein stability Academic Article
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Dynamically Driven Ligand Selectivity in Cyclic Nucleotide Binding Domains Academic Article
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Effect of copper on ion content in isolated mantle cells of the marine clam Mesodesma mactroides Academic Article
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Evaluation of DNA aptamers directed to thrombin as potential thrombus imaging agents Academic Article
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Evaluation of the effect of reactive sulfide on the acute toxicity of silver (I) toDaphnia magna. Part 1: Description of the chemical system Academic Article
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Evaluation of the effect of reactive sulfide on the acute toxicity of silver (I) toDaphnia magna. Part 2: Toxicity results Academic Article
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Evidence That Both Exosites on Thrombin Participate in Its High Affinity Interaction with Fibrin Academic Article
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Evidence for Allosteric Linkage between Exosites 1 and 2 of Thrombin Academic Article
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Evidence for Dual Binding Sites for 1,1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) in Insect Sodium Channels Academic Article
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Evidence of Kinetic Control of Ligand Binding and Staged Product Release in MurA (Enolpyruvyl UDP-GlcNAc Synthase)-Catalyzed Reactions, Academic Article
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Exosite 2-Directed Ligands Attenuate Protein C Activation by the Thrombin–Thrombomodulin Complex Academic Article
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Extension of the Single Amino Acid Chelate Concept (SAAC) to Bifunctional Biotin Analogues for Complexation of the M(CO)3+1 Core (M = Tc and Re): Syntheses, Characterization, Biotinidase Stability, and Avidin Binding Academic Article
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Fluorous ligand capture (FLC): a chemoselective solution-phase strategy for isolating 99mTc-labelled compounds in high effective specific activity Academic Article
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From Bench to Bedside Academic Article
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Functional Screening of Pharmacological Chaperones via Restoration of Enzyme Activity upon Denaturation Academic Article
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Functional characterization of estrogen receptor subtypes, ERα and ERβ, mediating vitellogenin production in the liver of rainbow trout Academic Article
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General occurrence of binding synergism in zinc proteases and its possible significance Academic Article
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Glucose‐regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders Academic Article
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HD1, a Thrombin-directed Aptamer, Binds Exosite 1 on Prothrombin with High Affinity and Inhibits Its Activation by Prothrombinase Academic Article
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High Glucose Up-regulates ADAM17 through HIF-1α in Mesangial Cells Academic Article
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High-throughput screening of holoprotein conformational stability by dynamic ligand exchange-affinity capillary electrophoresis Academic Article
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Histidine-rich Glycoprotein Binds Fibrin(ogen) with High Affinity and Competes with Thrombin for Binding to the γ′-Chain Academic Article
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Homology Model of Dihydropyridine Receptor: Implications for L-type Ca2+ Channel Modulation by Agonists and Antagonists Academic Article
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Homology Models of μ-Opioid Receptor with Organic and Inorganic Cations at Conserved Aspartates in the Second and Third Transmembrane Domains Academic Article
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HypF, a Carbamoyl Phosphate-converting Enzyme Involved in [NiFe] Hydrogenase Maturation Academic Article
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IL-15 and Type I Interferon Are Required for Activation of Tumoricidal NK Cells by Virus-Infected Dendritic Cells Academic Article
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Identification of Small Molecules that Sensitize Resistant Tumor Cells to Tumor Necrosis Factor-Family Death Receptors Academic Article
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Identification of novel catecholamine absorbing proteins in the central nervous system Academic Article
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Immunohistochemical and functional studies on calcium-sensing receptors in rat uterine smooth muscle Academic Article
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Implementation of the NMR CHEmical Shift Covariance Analysis (CHESCA): A Chemical Biologist’s Approach to Allostery Book
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Induction of Innate Immunity against Herpes Simplex Virus Type 2 Infection via Local Delivery of Toll-Like Receptor Ligands Correlates with Beta Interferon Production Academic Article
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Induction of hTERT Expression and Telomerase Activity by Estrogens in Human Ovary Epithelium Cells Academic Article
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Insulin resistance corresponds with a progressive increase in NOD1 in high fat diet-fed mice Academic Article
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Integrins Regulate Responsiveness to Slit Repellent Signals Academic Article
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Interaction of d-Tubocurarine with Potassium Channels: Molecular Modeling and Ligand Binding Academic Article
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Interactions of TonB-dependent transporter FoxA with siderophores and antibiotics that affect binding, uptake, and signal transduction Academic Article
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Interactions of drugs and toxins with permeant ions in potassium, sodium, and calcium channels. Academic Article
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KDBI: Kinetic Data of Bio-molecular Interactions database Academic Article
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Kappa-opioid receptor stimulation quickens pathogenesis of compulsive checking in the quinpirole sensitization model of obsessive-compulsive disorder (OCD). Academic Article
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Kinked-Helices Model of the Nicotinic Acetylcholine Receptor Ion Channel and Its Complexes with Blockers: Simulation by the Monte Carlo Minimization Method Academic Article
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KvAP-Based Model of the Pore Region of Shaker Potassium Channel Is Consistent with Cadmium- and Ligand-Binding Experiments Academic Article
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Label-Free Assay for Thermodynamic Analysis of Protein−Ligand Interactions: A Multivariate Strategy for Allosteric Ligand Screening Academic Article
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Lack of Association Between Thiazolidinediones and Macular Edema in Type 2 Diabetes Academic Article
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Leukemia targeting ligands isolated from phage display peptide libraries Academic Article
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Ligand action on sodium, potassium, and calcium channels: role of permeant ions Academic Article
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Ligand interactions at the active site of aspartate transcarbamoylase from Escherichia coli Academic Article
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Ligands of Diltiazem Binding Site: An Overview of Some Chemotypes Academic Article
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Lipid binding protein response to a bile acid library: a combined NMR and statistical approach Academic Article
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Liposomal delivery of gene therapy for ovarian cancer: a systematic review Academic Article
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Long wavelength optical control of glutamate receptor ion channels using a tetra-ortho-substituted azobenzene derivative Academic Article
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Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis Academic Article
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MDMA-evoked changes in the binding of dopamine D2receptor ligands in striatum of rats with unilateral serotonin depletion Academic Article
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Mapping Allostery through Equilibrium Perturbation NMR Spectroscopy Academic Article
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Mapping of Steroids Binding to 17β-Hydroxysteroid Dehydrogenase Type 1 Using Monte Carlo Energy Minimization Reveals Alternative Binding Modes Academic Article
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Mechanism of Selective Enzyme Inhibition through Uncompetitive Regulation of an Allosteric Agonist Academic Article
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Mechanism of acute silver toxicity inDaphnia magna Academic Article
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Metal insertion into NiFe-hydrogenases Academic Article
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Metal sulfides in oxygenated aquatic systems: implications for the biotic ligand model Academic Article
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Modeling P-Loops Domain of Sodium Channel: Homology with Potassium Channels and Interaction with Ligands Academic Article
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Modeling interactions between blocking and permeant cations in the NavMs channel Academic Article
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Molecular Modeling of Benzothiazepine Binding in the L-type Calcium Channel Academic Article
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Monte Carlo-energy minimization of correolide in the Kv1.3 channel: possible role of potassium ion in ligand-receptor interactions. Academic Article
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Monte Carlo-minimized energy profile of estradiol in the ligand-binding tunnel of 17?-hydroxysteroid dehydrogenase: Atomic mechanisms of steroid recognition Academic Article
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Mutual Protein-Ligand Conformational Selection Drives cGMP vs. cAMP Selectivity in Protein Kinase G Academic Article
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Neurotrophin-4/5 Alters Responses and Blocks the Effect of Monocular Deprivation in Cat Visual Cortex during the Critical Period Academic Article
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Non-sterol structural probes of the lanosterol 14α-demethylase from Saccharomyces cerevisiae Academic Article
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Novel platelet products, substitutes and alternatives Academic Article
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Noxious stimulation decreases substance P binding in rat spinal dorsal horn Academic Article
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Oncostatin M and TLR-4 Ligand Synergize to Induce MCP-1, IL-6, and VEGF in Human Aortic Adventitial Fibroblasts and Smooth Muscle Cells Academic Article
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Oncostatin M overexpression induces matrix deposition, STAT3 activation, and SMAD1 Dysregulation in lungs of fibrosis-resistant BALB/c mice Academic Article
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Opioid receptors in human neuroblastoma SH-SY5Y cells: Evidence for distinct morphine (μ) and enkephalin (δ) binding sites Academic Article
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Oxysterol Activators of Liver X Receptor and 9-cis-Retinoic Acid Promote Sequential Steps in the Synthesis and Secretion of Tumor Necrosis Factor-α from Human Monocytes Academic Article
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PPAR ligands decrease human airway smooth muscle cell migration and extracellular matrix synthesis Academic Article
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Peroxisome Proliferator-activated Receptor γ Ligands Differentially Modulate Muscle Cell Differentiation and MyoD Gene Expression via Peroxisome Proliferator-activated Receptor γ-dependent and -independent Pathways Academic Article
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Phenylalkylamines in calcium channels: computational analysis of experimental structures Academic Article
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Polymorphism in the Innate Immune Receptor SIRPα Controls CD47 Binding and Autoimmunity in the Nonobese Diabetic Mouse Academic Article
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Potassium Channel Block by a Tripartite Complex of Two Cationophilic Ligands and a Potassium Ion Academic Article
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Potassium, sodium, calcium and glutamate-gated channels: pore architecture and ligand action Academic Article
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Preparation and Evaluation of Radiolabeled Antibody Recruiting Small Molecules That Target Prostate-Specific Membrane Antigen for Combined Radiotherapy and Immunotherapy Academic Article
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Protein expression changes in the Sprague Dawley rat liver proteome following administration of peroxisome proliferator activated receptor α and γ ligands Academic Article
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Pseudomonas aeruginosa FpvB Is a High-Affinity Transporter for Xenosiderophores Ferrichrome and Ferrioxamine B Academic Article
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Quantification of the soluble leptin receptor in human blood by ligand-mediated immunofunctional assay. Conference Paper
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Quantitative autoradiography of ligands for dopamine receptors and transporters in brain of Göttingen minipig: Comparison with results in vivo Academic Article
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Quantum Mechanics/Molecular Mechanics Strategies for Docking Pose Refinement: Distinguishing between Binders and Decoys in Cytochrome c Peroxidase Academic Article
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REVIEW ARTICLE: The Role of Toll-Like Receptor Ligands/Agonists in Protection Against Genital HSV-2 Infection Academic Article
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Receptor domains of two-component signal transduction systems Academic Article
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Receptors for non-MHC ligands contribute to uterine natural killer cell activation during pregnancy in mice Academic Article
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Regional Localization within the Bone Marrow Influences the Functional Capacity of Human HSCs Academic Article
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Robustness of the BMP morphogen gradient in Drosophila embryonic patterning Academic Article
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Role of Half-of-Sites Reactivity and Inter-Subunit Communications in DAHP Synthase Catalysis and Regulation Academic Article
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Role of metal ions in ligand–receptor interaction: Insights from structural studies Academic Article
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SOCS3 inhibits the mesenchymal stromal cell secretory factor SDF-1-mediated improvement of islet function in non-obese diabetic mice Academic Article
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Screening of ligands for redox-active europium using magnetic resonance imaging Academic Article
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Signal Transduction within G-protein Coupled Receptors via an Ion Tunnel: A Hypothesis Academic Article
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Sodium channel activators: Model of binding inside the pore and a possible mechanism of action Academic Article
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Structural Model for Dihydropyridine Binding to L-type Calcium Channels Academic Article
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Structural Models of Ligand-Bound Sodium Channels Academic Article
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Structural model of a synthetic Ca2+ channel with bound Ca2+ ions and dihydropyridine ligand Academic Article
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Studies of Melatonin Effects on Epithelia Using the Human Embryonic Kidney-293 (HEK-293) Cell Line* Academic Article
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Subunit interactions in aspartate transcarbamylase. A model for the allosteric mechanism Academic Article
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Subunit interactions in aspartate transcarbamylase. The interaction between catalytic and regulatory subunits and the effect of ligands Academic Article
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Surface Immobilization of Structure-Switching DNA Aptamers on Macroporous Sol−Gel-Derived Films for Solid-Phase Biosensing Applications Academic Article
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Surface Phenotype and Functionality of WNV Specific T Cells Differ with Age and Disease Severity Academic Article
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Sweet Taste in Man: A Review Academic Article
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Synergistic binding of hydrophobic probes and zinc ligands to thermolysin Academic Article
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Synergistic binding of ligands to angiotensin-converting enzyme. Academic Article
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Synthesis and Evaluation of Radioiodinated Acyloxymethyl Ketones as Activity-Based Probes for Cathepsin B Academic Article
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Synthesis and Screening of Mono- and Di-Aryl Technetium and Rhenium Metallocarboranes. A New Class of Probes for the Estrogen Receptor Academic Article
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Synthesis and Screening of a Library of Re/Tc-Based Amyloid Probes Derived from β-Breaker Peptides Academic Article
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Synthesis, Characterisation, and Biodistribution of Radioiodinated C-Hydroxy-Carboranes Academic Article
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Synthesis, NMR, and X-ray Crystallographic Analysis of C-Hydrazino-C-Carboxycarboranes: Versatile Ligands for the Preparation of BNCT and BNCS Agents and 99mTc Radiopharmaceuticals Academic Article
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Synthesis, characterization, structure, molecular modeling studies and biological activity of sterically crowded Pt(II) complexes containing bis(imidazole) ligands Academic Article
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T Cells Engineered With Chimeric Antigen Receptors Targeting NKG2D Ligands Display Lethal Toxicity in Mice Academic Article
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T cell-mediated induction of thymic stromal lymphopoietin in differentiated human primary bronchial epithelial cells Academic Article
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Taming of a Poison: Biosynthesis of the NiFe-Hydrogenase Cyanide Ligands Academic Article
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Targeting macrophage scavenger receptor 1 promotes insulin resistance in obese male mice Academic Article
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Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis Academic Article
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The Effects of Extracellular Calcium-Sensing Receptor Ligands on the Contractility of Pregnant Human Myometrium In Vitro Academic Article
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The FMS-like tyrosine kinase-3 ligand/lung dendritic cell axis contributes to regulation of pulmonary fibrosis Academic Article
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The Notch Ligand Jagged-1 Represents a Novel Growth Factor of Human Hematopoietic Stem Cells Academic Article
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The direct effects of Toll-like receptor ligands on human NK cell cytokine production and cytotoxicity Academic Article
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The effects of pulp mill effluent on the sex steroid binding protein in white sucker (Catostomus commersoni) and longnose sucker (C. catostomus) Academic Article
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The platelet cytoskeleton stabilizes the interaction between αIIbβ3 and its ligand and induces selective movements of ligand-occupied integrin Article
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Toll‐Like Receptor (TLR)–3, but Not TLR4, Agonist Protects against Genital Herpes Infection in the Absence of Inflammation Seen with CpG DNA Academic Article
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Treatment of Non-Obese Diabetic (NOD)/Severe-Combined Immunodeficient Mice (SCID) With flt3 Ligand and Interleukin-7 Impairs the B-Lineage Commitment of Repopulating Cells After Transplantation of Human Hematopoietic Cells Academic Article
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UTILITY OF IN VITRO TEST METHODS TO ASSESS THE ACTIVITY OF XENOESTROGENS IN FISH Academic Article
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Using a Riboswitch Sensor to Examine Coenzyme B12 Metabolism and Transport in E. coli Academic Article
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Vimentin Exposed on Activated Platelets and Platelet Microparticles Localizes Vitronectin and Plasminogen Activator Inhibitor Complexes on Their Surface Academic Article
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[Molecular physiology of adrenoreceptors]. Academic Article
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[Productive conformations of ligands and topography of the alpha1-adrenoreceptor active site based on theoretical conformation analysis]. Academic Article
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[Topography of the active site of the noradrenaline neuronal membrane carrier based on the theoretical conformation analysis of inhibitors of neuronal catecholamine uptake]. Academic Article
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{ReIIICl3} Core Complexes with Bifunctional Single Amino Acid Chelates Academic Article