Fluorous ligand capture (FLC): a chemoselective solution-phase strategy for isolating 99m Tc-labelled compounds in high effective specific activity

A new approach for preparing (99m)Tc-labelled compounds in high effective specific activity was developed by utilizing a novel fluorous ligand capture (FLC) agent and a chemoselective filtration strategy. This paradigm eliminates the need to use HPLC to obtain technetium(I) based molecular imaging probes free from residual precursor.