Journal article
Dopamine D2 receptors quantified in vivo in human narcolepsy
Abstract
Assays in brain tissues from humans suffering from narcolepsy, and from genetically narcoleptic dogs have suggested that dopamine function may be disturbed in this condition. We have used the specific D2 receptor ligand N-(3-[18F]fluoropropyl)-spiperone and positron tomography to study a group of 6 well-characterized medication-free, HLA-DR2 DRW15 DW6-positive narcoleptic patients and a group of age- and sex-matched control individuals during …
Authors
MacFarlane JG; List SJ; Moldofsky H; Firnau G; Chen JJ; Szechtman H; Garnett S; Nahmias C
Journal
Biological Psychiatry, Vol. 41, No. 3, pp. 305–310
Publisher
Elsevier
Publication Date
February 1997
DOI
10.1016/s0006-3223(96)00003-0
ISSN
0006-3223