Transforming Growth Factor beta Concept

subject area of

• A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation  Journal Articles
• A Subset of Patients With Recurrent Spontaneous Abortion Is Deficient in Transforming Growth Factor β‐2‐Producing “Suppressor Cells” in Uterine Tissue Near the Placental Attachment Site  Journal Articles
• A Switch in TGF-β Signaling Explains Contradictory Findings in Pulmonary Arterial Hypertension  Journal Articles
• A large-scale candidate gene association study of age at menarche and age at natural menopause  Journal Articles
• A non-inflammatory form of immune competence prevails in acute pre-pubescent malnutrition: new evidence based on critical mRNA transcripts in the mouse  Journal Articles
• A novel profibrotic mechanism mediated by TGFβ‐stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells  Journal Articles
• A role for the TGFβ-Par6 polarity pathway in breast cancer progression  Journal Articles
• A therapeutic target for CKD: activin A facilitates TGFβ1 profibrotic signaling  Journal Articles
• A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer.  Journal Articles
• ATP stimulates Ca2+-waves and gene expression in cultured human pulmonary fibroblasts  Journal Articles
• Accumulation of chromotrope 2R positive cells in equine endometrium during early pregnancy and expression of transforming growth factor- 2 (TGF- 2)  Journal Articles
• Activin and transforming growth factor-β as local regulators of ovarian steroidogenesis in the goldfish  Journal Articles
• Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung.  Journal Articles
• Adenoviral Transfer of Murine Oncostatin M Elicits Periosteal Bone Apposition in Knee Joints of Mice, Despite Synovial Inflammation and Up-Regulated Expression of Interleukin-6 and Receptor Activator of Nuclear Factor-κB Ligand  Journal Articles
• Adenoviral gene transfer of bioactive TGFbeta1 to the rodent eye as a novel model for anterior subcapsular cataract.  Journal Articles
• Adenovirus-mediated decorin gene transfer prevents TGF-β-induced inhibition of lung morphogenesis  Journal Articles
• Ahnak depletion accelerates liver regeneration by modulating the TGF-β/Smad signaling pathway  Journal Articles
• Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis  Journal Articles
• Anchorage-independent colony growth of pulmonary fibroblasts derived from fibrotic human lung tissue.  Journal Articles
• Animal models of pulmonary fibrosis: how far from effective reality?  Journal Articles
• Biphasic activation of the BMP pathway patterns the Drosophila embryonic dorsal region  Journal Articles
• Bone cell matrix promotes the adhesion of human prostatic carcinoma cells via the α2β1 integrin  Journal Articles
• Ca²⁺/calmodulin-dependent protein kinase IIβ and IIδ mediate TGFβ-induced transduction of fibronectin and collagen in human pulmonary fibroblasts  Journal Articles
• Cadherin-11–mediated adhesion of macrophages to myofibroblasts establishes a profibrotic niche of active TGF-β  Journal Articles
• Characterization of murine pregnancy decidua transforming growth factor beta. I. Transforming growth factor beta 2-like molecules of unusual molecular size released in bioactive form  Journal Articles
• Cigarette Smoke Differentially Affects Eosinophilia and Remodeling in a Model of House Dust Mite Asthma  Journal Articles
• Cigarette smoke exposure aggravates air space enlargement and alveolar cell apoptosis inSmad3knockout mice  Journal Articles
• Clonally selected primitive endothelial cells promote occlusive pulmonary arteriopathy and severe pulmonary hypertension in rats exposed to chronic hypoxia  Journal Articles
• Colchicine attenuates renal injury in a model of hypertensive chronic kidney disease  Journal Articles
• Commentary: Seek (the nodes) and you shall find (the nodes)  Journal Articles
• Complex expression pattern of the CEF-4 cytokine in transformed and mitogenically stimulated cells.  Journal Articles
• Connective Tissue Growth Factor Is Crucial to Inducing a Profibrotic Environment in “Fibrosis-Resistant” Balb/c Mouse Lungs  Journal Articles
• Contrasting effects of myeloid dendritic cells transduced with an adenoviral vector encoding interleukin‐10 on organ allograft and tumour rejection  Journal Articles
• Counteracting effects of dexamethasone and α₂‐macroglobulin on inhibition of proliferation of normal and neoplastic rat hepatocytes by transforming growth factors‐β type 1 and type 2  Journal Articles
• Cytokine expression by neutrophils and macrophages in vivo: endotoxin induces tumor necrosis factor-alpha, macrophage inflammatory protein-2, interleukin-1 beta, and interleukin-6 but not RANTES or transforming growth factor-beta 1 mRNA expression in acute lung inflammation.  Journal Articles
• Cytokine modulation of muscarinic receptors in the murine intestine  Journal Articles
• Cytokines and pulmonary fibrosis.  Journal Articles
• Decidua-Associated Suppressor Cells in Abortion-Prone DBA/2-Mated CBA/J Mice that Release Bioactive Transforming Growth Factor β2-related Immunosuppressive Molecules Express a Bone Marrow-Derived Natural Suppressor Cell Marker and γδ8 T-Cell Receptor1  Journal Articles
• Dendritic cells expressing TGFβ/IL-10, and CHO cells with OX-2, increase graft survival  Journal Articles
• Differences in the Fibrogenic Response after Transfer of Active Transforming Growth Factor-β1 Gene to Lungs of “Fibrosis-prone” and “Fibrosis-resistant” Mouse Strains  Journal Articles
• Differential expression of nerve growth factor transcripts in glia and neurons and their regulation by transforming growth factor-β1  Journal Articles
• Differential inhibition of collagenase and interleukin-1alpha gene expression in cultured corneal fibroblasts by TGF-beta, dexamethasone, and retinoic acid.  Journal Articles
• Directed differentiation of neural cells to hypothalamic dopaminergic neurons  Journal Articles
• Divergent immune responses to house dust mite lead to distinct structural-functional phenotypes  Journal Articles
• Dual function of TGFβ in lens epithelial cell fate: implications for secondary cataract  Journal Articles
• Effects of adenoviral-mediated gene transfer of interleukin-10, interleukin-4, and transforming growth factor-β on the survival of axotomized retinal ganglion cells  Journal Articles
• Efficacy and Safety of Recombinant Human Bone Morphogenetic Protein-2/Calcium Phosphate Matrix for Closed Tibial Diaphyseal Fracture  Journal Articles
• Electrophysiological characterization of voltage-dependent calcium currents and TRPV4 currents in human pulmonary fibroblasts  Journal Articles
• Endometrial epithelial cell response to semen from HIV-infected men during different stages of infection is distinct and can drive HIV-1-long terminal repeat  Journal Articles
• Enhancement of dendritic cell tolerogenicity by genetic modification using adenoviral vectors encoding cDNA for TGFβ1  Journal Articles
• Eosinophils in chronically inflamed human upper airway tissues express transforming growth factor beta 1 gene (TGF beta 1).  Journal Articles
• Epidermal Growth Factor Receptor and Transforming Growth Factor-β Signaling Contributes to Variation for Wing Shape in Drosophila melanogaster  Journal Articles
• Epithelial Expression of Profibrotic Mediators in a Model of Allergen-Induced Airway Remodeling  Journal Articles
• Epithelium-specific adenoviral transfer of a dominant-negative mutant TGF-β type II receptor stimulates embryonic lung branching morphogenesis in culture and potentiates EGF and PDGF-AA  Journal Articles
• Expression and actions of transforming growth factors during human follicular development  Journal Articles
• FGF19 Is Downregulated in Idiopathic Pulmonary Fibrosis and Inhibits Lung Fibrosis in Mice  Journal Articles
• Fluorofenidone Offers Improved Renoprotection at Early Interventions during the Course of Diabetic Nephropathy in db/db Mice via Multiple Pathways  Journal Articles
• Gene Transfer of Transforming Growth Factor-β1 to the Rat Peritoneum  Journal Articles
• Generation of lymphokine-activated killer cells in human ovarian carcinoma ascitic fluid: Identification of transforming growth factor-β as a suppressive factor  Journal Articles
• Genetic Modifiers of Lung Disease in Cystic Fibrosis  Journal Articles
• Glypican LON-2 Is a Conserved Negative Regulator of BMP-like Signaling in Caenorhabditis elegans  Journal Articles
• Growth and Colony‐Stimulating Factors Mediate Eosinophil Fibroblast Interactions in Chronic Airway Inflammationa  Journal Articles
• Growth factors in the anterior segment: role in tissue maintenance, wound healing and ocular pathology  Journal Articles
• Helminth antigen-based strategy to ameliorate inflammation in an experimental model of colitis  Journal Articles
• HuR drives lung fibroblast differentiation but not metabolic reprogramming in response to TGF-β and hypoxia  Journal Articles
• IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro  Journal Articles
• Idiopathic epiretinal membranes: cell type, growth factor expression, and fluorescein angiographic and retinal photographic correlations  Conferences
• Immunology: CD56+ lymphoid cells in human first trimester pregnancy decidua as a source of novel transforming growth factor-β2-related immunosuppressive factors  Journal Articles
• Impact of intranasal budesonide on immune inflammatory responses and epithelial remodeling in chronic upper airway inflammation  Journal Articles
• In vitro effects of bone- and platelet-derived transforming growth factor-? on the growth of Walker 256 carcinosarcoma cells  Journal Articles
• Induction of a fibrogenic response in mouse colon by overexpression of monocyte chemoattractant protein 1  Journal Articles
• Induction of interleukin-1/and interleukin-8 mRNAs and proteins by TGFβ1 in rat lung alveolar epithelial cells  Journal Articles
• Influenza Promotes Collagen Deposition via αvβ6 Integrin-mediated Transforming Growth Factor β Activation  Journal Articles
• Interactions of corneal cells with transforming growth factor β2‐modified poly dimethyl siloxane surfaces  Journal Articles
• Intestinal epithelial cell-derived integrin αβ6 plays an important role in the induction of regulatory T cells and inhibits an antigen-specific Th2 response  Journal Articles
• Involvement of astrocytes in purine‐mediated reparative processes in the brain  Journal Articles
• Lactobacillus paracasei normalizes muscle hypercontractility in a murine model of postinfective gut dysfunction  Journal Articles
• Lens-Specific Expression of TGF-β Induces Anterior Subcapsular Cataract Formation in the Absence of Smad3  Journal Articles
• M2-polarized and tumor-associated macrophages alter NK cell phenotype and function in a contact-dependent manner  Journal Articles
• MMP9 Differentially Regulates Proteins Involved in Actin Polymerization and Cell Migration during TGF-β-Induced EMT in the Lens  Journal Articles
• Matrix Metalloproteinase 3 Is a Mediator of Pulmonary Fibrosis  Journal Articles
• Matrix Metalloproteinase Inhibitors Suppress Transforming Growth Factor-β-Induced Subcapsular Cataract Formation  Journal Articles
• Matrix metalloproteinase 9 is associated with peritoneal membrane solute transport and induces angiogenesis through β-catenin signaling  Journal Articles
• Mechanisms Underlying the Maintenance of Muscle Hypercontractility in a Model of Postinfective Gut Dysfunction  Journal Articles
• Mesenchymal stromal cells cross-present soluble exogenous antigens as part of their antigen-presenting cell properties  Journal Articles
• Metastatic Growth from Dormant Cells Induced by a Col-I–Enriched Fibrotic Environment  Journal Articles
• Micro-computed tomography of pulmonary fibrosis in mice induced by adenoviral gene transfer of biologically active transforming growth factor-β1  Journal Articles
• Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis  Journal Articles
• Modulation of pulmonary fibrosis by IL-13Rα2  Journal Articles
• Molecules in focus Transforming growth factor-beta (TGF-β)  Journal Articles
• Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8–mediated activation of TGF-β  Journal Articles
• Myostatin promotes a fibrotic phenotypic switch in multipotent C3H 10T1/2 cells without affecting their differentiation into myofibroblasts  Journal Articles
• Neuroimmunologic and Neurotrophic Interactions in Autism Spectrum Disorders: Relationship to Neuroinflammation  Journal Articles
• Nuclear translocation of myocardin-related transcription factor-A during transforming growth factor beta-induced epithelial to mesenchymal transition of lens epithelial cells.  Journal Articles
• Overexpression of Tumor Necrosis Factor-α Diminishes Pulmonary Fibrosis Induced by Bleomycin or Transforming Growth Factor-β  Journal Articles
• Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation  Journal Articles
• Overexpression of granulocyte-macrophage colony-stimulating factor induces pulmonary granulation tissue formation and fibrosis by induction of transforming growth factor-beta 1 and myofibroblast accumulation.  Journal Articles
• PHENOTYPE, FUNCTION, AND IN VIVO MIGRATION AND SURVIVAL OF ALLOGENEIC DENDRITIC CELL PROGENITORS GENETICALLY ENGINEERED TO EXPRESS TGF-??1,2  Journal Articles
• Partial Loss of USP9X Function Leads to a Male Neurodevelopmental and Behavioral Disorder Converging on Transforming Growth Factor β Signaling  Journal Articles
• Peptide immunotherapy in allergic asthma generates IL-10–dependent immunological tolerance associated with linked epitope suppression  Journal Articles
• Peroxisome proliferator-activated receptor-γ agonist pioglitazone fails to attenuate renal fibrosis caused by unilateral ureteral obstruction in mice  Journal Articles
• Platelet derived growth factor B and epithelial mesenchymal transition of peritoneal mesothelial cells  Journal Articles
• Porcine Collagenase from Synovial Fibroblasts: cDNA Sequence and Modulation of Expression of RNA In Vitro by Various Cytokines  Journal Articles
• Progressive Transforming Growth Factor β1–induced Lung Fibrosis Is Blocked by an Orally Active ALK5 Kinase Inhibitor  Journal Articles
• Prostaglandin E₂ inhibits profibrotic function of human pulmonary fibroblasts by disrupting Ca²⁺ signaling  Journal Articles
• Proteoglycans decorin and biglycan differentially modulate TGF-β-mediated fibrotic responses in the lung  Journal Articles
• Pulmonary overexpression of IL-10 augments lung fibrosis and Th2 responses induced by silica particles  Journal Articles
• Quiescence-dependent activation of the p20K promoter in growth-arrested chicken embryo fibroblasts.  Journal Articles
• Rapamycin inhibits transforming growth factor β‐induced peritoneal angiogenesis by blocking the secondary hypoxic response  Journal Articles
• Re-evaluation of Fibrogenic Cytokines in Lung Fibrosis  Journal Articles
• Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity  Journal Articles
• Regulation of Myogenic Differentiation by Androgens: Cross Talk between Androgen Receptor/ β-Catenin and Follistatin/Transforming Growth Factor-β Signaling Pathways  Journal Articles
• Release of a transforming growth factor (TGF)-beta 2-related suppressor factor from postimplantation murine decidual tissue can be correlated with the detection of a subpopulation of cells containing RNA for TGF-beta 2.  Journal Articles
• Reversal of suppression of lymphokine-activated killer cells by transforming growth factor-β in ovarian carcinoma ascitic fluid requires interleukin-2 combined with anti-CD3 antibody  Journal Articles
• Robustness of the BMP morphogen gradient in Drosophila embryonic patterning  Journal Articles
• Role of insulin-like growth factor binding proteins (IGFBPs) in breast cancer proliferation and metastasis.  Journal Articles
• Role of the COX2-PGE₂ axis in S. pneumoniae-induced exacerbation of experimental fibrosis  Journal Articles
• SERUM TGF-β IN THERMALLY INJURED RATS  Journal Articles
• SMAD3-dependent and -independent pathways in glomerular injury associated with experimental glomerulonephritis  Journal Articles
• SREBP inhibition ameliorates renal injury after unilateral ureteral obstruction  Journal Articles
• Serum‐dependent Modulation of the we 1 Plasminogen Activator Inhibitor Binding to Endothelial Cell Surfaces  Journal Articles
• Smad3 Null Mice Develop Airspace Enlargement and Are Resistant to TGF-β-Mediated Pulmonary Fibrosis  Journal Articles
• Smad3 Signaling Involved in Pulmonary Fibrosis and Emphysema  Journal Articles
• Spatial-specific TGF-β1 adenoviral expression determines morphogenetic phenotypes in embryonic mouse lung  Journal Articles
• Stress-Induced Murine Abortion Associated with Substance P-Dependent Alteration in Cytokines in Maternal Uterine Decidua1  Journal Articles
• Stress‐Triggered Abortion: Inhibition of Protective Suppression and Promotion of Tumor Necrosis Factor‐α (TNF‐α) Release as a Mechanism Triggering Resorptions in Mice  Journal Articles
• Subgroup-specific structural variation across 1,000 medulloblastoma genomes  Journal Articles
• Synergy in Induction of Increased Renal Allograft Survival after Portal Vein Infusion of Dendritic Cells Transduced to Express TGFβ and IL-10, along with Administration of CHO Cells Expressing the Regulatory Molecule OX-2  Journal Articles
• TGF-β, Eosinophils and IL-13 in Allergic Airway Remodeling: A Critical Appraisal with Therapeutic Considerations  Journal Articles
• TGF-β and Smad3 Signaling Link Inflammation to Chronic Fibrogenesis  Journal Articles
• TGF-β effects on epithelial ion transport and barrier: reduced Cl⁻ secretion blocked by a p38 MAPK inhibitor  Journal Articles
• TGF-β induces assembly of a Smad2–Smurf2 ubiquitin ligase complex that targets SnoN for degradation  Journal Articles
• TGF-β, Smad3 and the process of progressive fibrosis  Journal Articles
• TGF-β1 gene transfer to the mouse colon leads to intestinal fibrosis  Journal Articles
• TGFβ Programs Central Memory Differentiation inEx Vivo–Stimulated Human T Cells  Journal Articles
• TGFβ-induced RhoA activation and fibronectin production in mesangial cells require caveolae  Journal Articles
• TH1/TH2,3 Imbalance due to Cytokine‐Producing NK, γδ T and NK‐γδ T Cells in Murine Pregnancy Decidua in Success or Failure of Pregnancy  Journal Articles
• Targeted Deletion ofAP-2α Leads to Disruption in Corneal Epithelial Cell Integrity and Defects in the Corneal Stroma  Journal Articles
• Targeting Genes for Treatment in Idiopathic Pulmonary Fibrosis: Challenges and Opportunities, Promises and Pitfalls  Journal Articles
• Temporal changes in MMP mRNA expression in the lens epithelium during anterior subcapsular cataract formation  Journal Articles
• Testosterone inhibits transforming growth factor-β signaling during myogenic differentiation and proliferation of mouse satellite cells: Potential role of follistatin in mediating testosterone action  Journal Articles
• The Human Papilloma Virus E7 Oncoprotein Inhibits Transforming Growth Factor-β Signaling by Blocking Binding of the Smad Complex to Its Target Sequence  Journal Articles
• The Influence of Macrophages and the Tumor Microenvironment on Natural Killer Cells  Journal Articles
• The Role of the Extracellular Matrix in Articular Chondrocyte Regulation  Conferences
• The TGFβ-ERK pathway contributes to Notch3 upregulation in the renal tubular epithelial cells of patients with obstructive nephropathy  Journal Articles
• The breast tumor microenvironment alters the phenotype and function of natural killer cells  Journal Articles
• The combination of IGF-I and KGF cDNA improves dermal and epidermal regeneration by increased VEGF expression and neovascularization  Journal Articles
• The gene transfer of soluble VEGF type I receptor (Flt-1) attenuates peritoneal fibrosis formation in mice but not soluble TGF-β type II receptor gene transfer  Journal Articles
• The renal expression of transforming growth factor-beta isoforms and their receptors in acute and chronic experimental diabetes in rats.  Journal Articles
• The role of WNT5A and Ror2 in peritoneal membrane injury  Journal Articles
• The sex-limited effects of mutations in the EGFR and TGF-β signaling pathways on shape and size sexual dimorphism and allometry in the Drosophila wing  Journal Articles
• Therapeutic strategies to target connective tissue growth factor in fibrotic lung diseases  Journal Articles
• Transcriptional profiling and regulation of the extracellular matrix during muscle regeneration  Journal Articles
• Transfer of Tumor Necrosis Factor-α to Rat Lung Induces Severe Pulmonary Inflammation and Patchy Interstitial Fibrogenesis with Induction of Transforming Growth Factor-β1 and Myofibroblasts  Journal Articles
• Transfer of the Active Form of Transforming Growth Factor-β1 Gene to Newborn Rat Lung Induces Changes Consistent with Bronchopulmonary Dysplasia  Journal Articles
• Transforming Growth Factor-β Gene Transfer to the Lung Induces Myofibroblast Presence and Pulmonary Fibrosis  Conferences
• Transforming Growth Factor-β Regulates House Dust Mite–induced Allergic Airway Inflammation but Not Airway Remodeling  Journal Articles
• Transforming Growth Factor-β1-Mediated Neuroprotection against Excitotoxic Injuryin Vivo  Journal Articles
• Transforming Growth Factor-β: Activation by Neuraminidase and Role in Highly Pathogenic H5N1 Influenza Pathogenesis  Journal Articles
• Transforming Growth Factor-β: Importance in Long-Term Peritoneal Membrane Changes  Conferences
• Transforming Growth Factor‐β2‐Related‐Decidual Suppressor Factor Is Not Related to TJ6 Protein  Journal Articles
• Transforming Growth Factor–β Evokes Ca²⁺ Waves and Enhances Gene Expression in Human Pulmonary Fibroblasts  Journal Articles
• Transforming growth factor beta 1 (TGF beta 1) gene expression by eosinophils in asthmatic airway inflammation.  Journal Articles
• Transforming growth factor beta upregulates the integrin-mediated adhesion of human prostatic carcinoma cells to type I collagen.  Journal Articles
• Transforming growth factor beta1 acts as an inducer of matrix metalloproteinase expression and activity in human bone-metastasizing cancer cells.  Journal Articles
• Transforming growth factor β-induced peritoneal fibrosis is mouse strain dependent*  Journal Articles
• Transforming growth factor-β1 enhances IgG and IgA sheep red blood cell responses  Journal Articles
• Transfusion‐related immunomodulation due to peripheral blood dendritic cells expressing the CD200 tolerance signaling molecule and alloantigen  Journal Articles
• Transient Overexpression of TGF-β1 Induces Epithelial Mesenchymal Transition in the Rodent Peritoneum  Journal Articles
• Transient Transgene Expression of Decorin in the Lung Reduces the Fibrotic Response to Bleomycin  Journal Articles
• Transient expression of IL-1β induces acute lung injury and chronic repair leading to pulmonary fibrosis  Journal Articles
• Transient transgene expression of decorin in the lung reduces the fibrotic response to bleomycin  Journal Articles
• UNC-129 regulates the balance between UNC-40 dependent and independent UNC-5 signaling pathways  Journal Articles
• Understanding the Role of Yes-Associated Protein (YAP) Signaling in the Transformation of Lens Epithelial Cells (EMT) and Fibrosis  Journal Articles
• VEGF, FGF-2 and TGFβ expression in the normal and regenerating epidermis of geckos: implications for epidermal homeostasis and wound healing in reptiles  Journal Articles
• Vagus nerve integrity and experimental colitis  Journal Articles
• Vascular Endothelial Growth Factor Expression in Peritoneal Mesothelial Cells Undergoing Transdifferentiation  Journal Articles
• [Autocrine activation of fibroblasts following irradiation].  Journal Articles
• β-Catenin/Smad3 Interaction Regulates Transforming Growth Factor-β-Induced Epithelial to Mesenchymal Transition in the Lens  Journal Articles