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A Subset of Patients With Recurrent Spontaneous...
Journal article

A Subset of Patients With Recurrent Spontaneous Abortion Is Deficient in Transforming Growth Factor β‐2‐Producing “Suppressor Cells” in Uterine Tissue Near the Placental Attachment Site

Abstract

PROBLEM: To determine if patients with unexplained recurrent miscarriage have a deficiency of decidual immunosuppressor cells that produce transforming growth factor beta type 2, as has been found in mice with abortion due to rejection and/or trophoblast failure. METHODS: Decidual biopsy specimens were taken as near to the placental attachment site as possible under ultrasound guidance from first trimester legal termination (control) patients …

Authors

LEA RG; UNDERWOOD J; FLANDERS KC; HIRTE H; BANWATT D; FINOTTO S; OHNO I; DAYA S; HARLEY C; MICHEL M

Journal

American Journal Of Reproductive Immunology, Vol. 34, No. 1, pp. 52–64

Publisher

Wiley

Publication Date

July 1995

DOI

10.1111/j.1600-0897.1995.tb00919.x

ISSN

1046-7408