Journal article
Counteracting effects of dexamethasone and α2‐macroglobulin on inhibition of proliferation of normal and neoplastic rat hepatocytes by transforming growth factors‐β type 1 and type 2
Abstract
Primary cultures of hepatocytes isolated from normal F-344 rats or from F-344 rats with hepatocellular carcinomas generated by a 2-step model of chemical carcinogenesis were used to determine if dexamethasone (DEX) or alpha 2-macroglobulin (alpha 2M) modify the ability of transforming growth factors-beta type I (TGF-beta I) and type 2 (TGF-beta 2) to inhibit labelling index of hepatocytes cultured continuously with or without epidermal growth …
Authors
Wollenberg GK; Lamarre J; Semple E; Farber E; Gauldie J; Hayes MA
Journal
International Journal of Cancer, Vol. 47, No. 2, pp. 311–316
Publisher
Wiley
Publication Date
January 21, 1991
DOI
10.1002/ijc.2910470223
ISSN
0020-7136