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SERUM TGF-β IN THERMALLY INJURED RATS
Journal article

SERUM TGF-β IN THERMALLY INJURED RATS

Abstract

A severe thermal injury is commonly associated with immune suppression and increased susceptibility to sepsis, frequently leading to multiple organ failure. Transforming growth factor-beta (TGF-beta) is a potent immunosuppressive cytokine involved in complications associated with major trauma. Interleukin- 4 (IL-4) is thought to synergize the immunosuppressive activity of TGF-beta by promoting naive lymphocytes to differentiate and generate …

Authors

Varedi M; Jeschke MG; Englander EW; Herndon DN; Barrow RE

Journal

Shock, Vol. 16, No. 5, pp. 380–382

Publisher

Wolters Kluwer

Publication Date

11 2001

DOI

10.1097/00024382-200116050-00010

ISSN

1073-2322